ISI Impact Factor (2004): 1.096

Editor-in-Chief
Prof. Yi-Fei WANG,

　

Parameter	Adrenalectomized Control	Adrenalectomy+ Hydrocortisone 1 mg	Adrenalectomy+ Hydrocortisone 2 mg	Adrenalectomy+ Hydrocortisone 4 mg
Post-treatment Day 2 (postoperative Day 9)
Aryl sulphatase Lactic dehydrogenase Leucine aminopeptidase Alkaline phosphatase Acid phosphatase	0.174±0.005 4.7±0.5 0.084±0.002 44.63±1.18 22.93±4.24	0.286±0.021c 6.1±1.0 0.120±0.028 49.24±0.48c 58.47±2.43c	0.69±0.06c 44.56±0.19c 3.675±0.115c 51.17±0.06c 44.77±1.76c	5.02±0.12c   54.5±1.2c 16.11±0.47c 152.2±11.3c   303.77±11.23c
Day 4
Aryl sulphatase   Lactic dehydrogenase   Leucine aminopeptidase   Alkaline phosphatase   Acid phosphatase	0.471±0.008   6.3±1.9   0.114±0.005   15.4±1.4   20.5±4.1	0.672±0.094   16.4±1.9c 0.172±0.017b    59.2±7.1c 38.5±3.4b	0.716±0.009c 9.9±0.6   4.601±0.216c   51.610±0.020c   29.1±1.0	0.7124±0.0016c   12.74±0.17b   1.007±0.083c   17.22±0.21   32.5±1.5b
Day 8
Aryl sulphatase   Lactic dehydrogenase   Leucine aminopeptidase   Alkaline phosphatase   Acid phosphatase	0.614±0.004   8.8±0.3   0.140±0.004   10.12±0.10   20.49±3.42	2.314±0.012c   10.8±0.8 1.14±0.04c 12.00±0.84   61.63±7.30c	2.0710±0.0006c 12.3±0.4c 0.68±0.05c 22.300±0.004c 46.56±0.29c	2.411±0.073   12.0±1.1b 11.46±0.05c 12.84±1.21b 42.60±2.26c
Day 12
Aryl sulphatase   Lactic dehydrogenase   Leucine aminopeptidase   Alkaline phosphatase   Acid phosphatase	0.7186±0.0018   9.99±0.08   0.1817±0.0027   9.24±0.03   24.7±1.9	2.982±0.049c   15.38±0.41c   1.02±0.26c   32.75±0.22c   29.7±4.7	1.070±0.001c   14.85±0.32c   0.437±0.013c   20.43±0.03c   48.9±0.7c	1.397±0.050c   31.67±0.08c   2.05±0.04c   34.49±1.00c   102.1±6.2c
Day 16
Aryl sulphatase   Lactic dehydrogenase   Leucine aminopeptidase   Alkaline phosphatase   Acid phosphatase	0.814±0.018   34.77±1.35   2.344±0.027   6.71±0.98   27.9±6.8	0.96±0.23c   74.88±1.29c   2.90±0.04c   25.60±2.52c   50.5±5.4b	0.9897±0.0009c   74.86±0.59c   2.72±0.03c   10.465±0.004c 43.1±1.1	0.9982±0.0015c   68.20±0.10c   3.055±0.019c   31.36±0.11c   98.7±1.6c

^bP<0.05, ^cP<0.01, compared with control.
Units: Aryl sulphatase, alkaline phosphatase and acid phosphatase (μmol of  p-nitrophenol liberated/ mg protein/h).   
Lactic dehydrogenase (LDH Units/mg/g protein/h).
Leucine aminopeptidase (μmol of β-naphthylamine liberated/mg protein/h).