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Abstract

Volume 14, Issue 3 (May 2012) 14, 415–418; 10.1038/aja.2011.146

Inherited susceptibility for aggressive prostate cancer

William B Isaacs

Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. wisaacs@jhmi.edu

Correspondence: Dr WB Isaacs, (wisaacs@jhmi.edu)

Received 16 March 2012; Revised 30 March 2012; Accepted 30 March 2012; Advance online publication 30 April 2012

Abstract

Whether or not there is inherited basis for prostate cancer aggressiveness is not clear, but advances in DNA analysis should provide an answer to this question in the very near future.

Keywords: aggressiveness; germline; Genome Wide Association Studies; GWAS; inherited; linkage; mutation; single nucleotide polymorphisms; SNPs; susceptibility

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