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Volume 9, Issue 2 (March 2007) 9, 275–279; 10.1111/j.1745-7262.2007.00235.x
Extragastrointestinal stromal tumor presenting as a scrotal mass: an unusual case
Seok-Ho Kang, Myung-Joon Kim, Min-Gu Park, Hong-Seok Park, Du-Geon Moon, Deuk-Jae Sung, Hyun-Chul Kim, Yang-Seok Chae, Jun Cheon and Je-Jong Kim
1.Department of Urology, Korea University School of Medicine, Seoul 136-705, Korea
2.Department of Radiology, Korea University School of Medicine, Seoul 136-705, Korea
3.Department of Pathology, Korea University School of Medicine, Seoul 136-705, Korea
Correspondence: Dr Je-Jong Kim, Department of Urology, Korea University Hospital, Seoul 136-705, Korea. Fax: +82-2-928-7864. E-mail: jjkim98@korea.ac.kr
Received 15 June 2006; Accepted 28 August 2006.
| Abstract |
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We describe an unusual case of extragastrointestinal stromal tumor (EGIST) presenting as a scrotal mass. A 71-year-old man presented with a gradually enlarging scrotal mass with a 20-year duration. Physical examination revealed a huge (as large as volleyball), round, nontender mass occupying the whole scrotum, which was resected completely. Clinical and radiological findings did not comply with any other primary site disease. Under histological examination, the tumor showed a spindle cell pattern with low cellularity, absence of necrotic and mitotic features. Immunohistochemical anlaysis revealed the tumor reactive for CD117 and CD34, while negative for smooth muscle actin, desmin and S-100 protein. To our knowledge, this is the first reported case of an EGIST involving the scrotum.
Keywords: extragastrointestinal stromal tumor, scrotum, immunohistochemistry
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