Volume 25, Issue 1 (January 2023) 25, 132–136; 10.4103/aja202223
Age-related changes for the predictors of benign prostatic hyperplasia in Chinese men aged 40 years or older
Wei-Hao Shao1, Cai-Fang Zheng1, Yong-Chao Ge2, Xiao-Rui Chen1, Bo-Wen Zhang1, Gai-Li Wang1, Wei-Dong Zhang1
1 Department of Epidemiology, School of Public Health, Zhengzhou University, Zhengzhou 450001, China 2 Department of Urology, The Third People's Hospital of Zhengzhou, Zhengzhou 450000, China
Correspondence: Dr. WD Zhang (imooni@163.com)
29-Apr-2022
Abstract |
A cross-sectional study was conducted to estimate the age-stratified normal levels and age-related changes in the risk predictors of benign prostatic hyperplasia (BPH) progression. A total of 4706 male participants aged 40 years or older in Zhengzhou (China) were enrolled. The values of the International Prostate Symptom Score (IPSS), prostate-specific antigen (PSA), prostate volume (PV), and postvoid residual urine volume (PVR) significantly increased with age. Nonlinear relationships between age and IPSS scores ≥8 (P for nonlinearity = 0.046), PSA level ≥1.6 ng ml–1, PV ≥31 ml, or PVR ≥39 ml (all P for nonlinearity <0.001) were observed. After the age of 61 years, the risk indicators related to BPH progression were positively correlated with age (odds ratio [OR] >1), regardless of the predictors of the IPSS score, PSA level, PV, or PVR; and the OR values increased gradually. Therefore, after the age of 61 years, the risk predictors related to BPH progression were positively correlated with age.
Keywords: aging; lower urinary tract symptoms; postvoid residual urine volume; prostate-specific antigen; prostate volume
Full Text |
PDF |
|
|
Browse: 257 |
|