December 10, 2004

 

Junichi Fujii

 

Citizenship:     Japan

 

Title:             Ph. D., Professor

 

Address:          Department of Biomolecular Function

                 Major of Environmental Life Science

                 Graduate School of Medical Science

                 Yamagata University

                 2-2-2 Iidanishi, Yamagata 990-9585

                 JAPAN

                 Tel:       +81-23-628-5227

                 FAX:      +81-23-628-5230

                 e-mail: jfujii@med.id.yamagata-u.ac.jp

 

Education:

   1982         B. S., Shizuoka University, Shizuoka, Japan

   1984         M. S., Shizuoka University, Shizuoka, Japan

   1988         Ph. D., Osaka University Medical School, Osaka, Japan

 

Research Experience:

   1987-1988  Research fellow, at the Banting and Best Department of

              Medical Research, University of Toronto, Toronto, Canada

   1988-1990  Postdoctoral fellow, at the above Department

   1990-1991  Postdoctoral fellow of Japan Society for the Promotion of

Science,

  Department of Biochemistry, Osaka University Medical School, Japan

   1991-1992   Research Associate in the same Department

   1992-1996   Assistant Professor in the same Department

   1996-1999   Associate Professor in the same Department

   1999-2004   Professor, Department of Biochemistry

                                    Yamagata University School of Medicine

   2004-present Professor, Department of Biomolecular Function

                  Major of Environmental Life Science

                  Graduate School of Medical Science, Yamagata University

 

 


Junichi FUJII---Original Papers--- December 10, 2004

 (IF; Impact Factor total 104, CI; Citation Index)

 

1.          Shinpei Yamada, Junichi Fujii, and Hajime Katayama

Sarcoplasmic Reticulum Ca-ATPase: Distinction of Phosphoenzyme Formed from Mg ATP and Ca ATP as Substrates and Interconversion of the Phosphoenzymes by Mg2+ and Ca2+.

J. Biochem. 100: 1329-1342 (1986)  (IF=2.191, CI=18)

 

2.          Junichi Fujii, Masaaki Kadoma, Michihiko Tada, Hiroko Toda, and Fumio Sakiyama.

Characterizaion of Structural Unit of Phospholamban by Amino Acid Sequencing and Electrophoretic Analysis

Biochem. Biophys. Res. Commun. 138: 1044-1050 (1986)  (IF=3.161, CI=45)

 

3.          Junichi Fujii, Atsuko Ueno, Katsuhiko Kitano, Shoji Tanaka, Masaaki Kadoma, and Michihiko Tada.

Complete Complementary DNA-derived Amino Acid Sequence of Canine Cardiac Phospholamban.

J. Clin. Invest. 79: 301-304 (1987)  (IF=10.921, CI=135)

 

4.          Atsuko Uyeda, Katsuhiko Kitano, Junichi Fujii, Masaaki Kadoma, Michihiko Tada, and Shoji Tanaka. 

The cDNA sequence of the Major Phospholamban mRNA in Canine Cardiac Muscle

Nucleic Acids Res. 15: 6738 (1987)  (IF=5.748, CI=7)

 

5.          Junichi Fujii, Jonathan Lytton, Michihiko Tada, and David H. MacLennan

Rabbit Cardiac and Slow-twitch Muscle Express the Same Phospholamban Gene.

FEBS Lett. 227: 51-55 (1988)  (IF=3.720, CI=63)

 

6.          Ryozo Nagai, Angel Zarain-Herzberg, Christopher J. Brandl, Junichi Fujii, Michihiko Tada, David H. MacLennan, Norman R. Alpert, and Muthu Periasamy

Regulation of Myocardial Ca-ATPase and Phospholamban mRNA Expression in Response to Pressure Overload and Thyroid Hormone.

Proc. Natl. Acad. Sci. USA. 86: 2966-2970 (1989)  (IF=10.260, CI=251)

 

7.          Ekkehard Leberer, Kar-Thomas Hartner, Christopher, J. Brandl, Junichi Fujii, Michihiko Tada, David H. MacLennan, and Dirk Pette

Slow/cardiac Sarcoplasmic Reticulum Ca2+-ATPase and Phospholamban mRNAs are Expressed in Chronically Stimulated Rabbit Fast-twitch Muscle.

Eur. J. Biochem. 185: 51-54 (1989)  (IF=3.307, CI=64)

 

8.          Junichi Fujii, Kei Maruyama, Michihiko Tada, and David H. MacLennan

Expression and Site-specific Mutagenesis of Phospholamban: Studies of Residues Involved in Phosphorylation and Pentamer Formation.

J. Biol. Chem. 264: 12950-12955 (1989)  (IF=7.666, CI=74)

 

9.          Kei Maruyama, David M. Clarke, Junichi Fujii, Giuseppe Inesi, Tip W. Loo, and David H. MacLennan

Functional Consequences of Alterations to Amino Acids Located in the Catalytic (Isolucine 348 to Threonine 357) and Nucleotide-binding Domain of the Ca2+-ATPase of Sarcoplasmic Reticulum.

J. Biol. Chem. 264: 13038-13042 (1989)  (IF=7.666, CI=89)

10.      Francesco Zorzato, Junichi Fujii, Kinya Otsu, Michael Phillips, N. Michael Green, F. Anthony Lai, Gerhard Meissner, and David H. MacLennan. 

Molecular Cloning of cDNA Encoding Human and Rabbit Forms of the Ca2+ Release Channel (Ryanodine Receptor) of Skeletal Muscle Sarcoplasmic Reticulum.

J. Biol. Chem. 265: 2244-2256 (1990)  (IF=7.666, CI=429)

 

11.      David H. MacLennan, Chatherine Duff, Francesco Zorzato, Junichi Fujii, Michael

Phillips, Robert G. Korneluk, Wanda Frodis, Beverley A. Britt, and Ronald G. Worton.

The Ryanodine Receptor Gene is a Candidate Gene for the Predisposition to Malignant Hyperthermia.

Nature 343: 559-561 (1990)  (IF=29.491 CI=331)

 

12.      Junichi Fujii, Huntington F. Willard, and David H. MacLennan

Characterization and Localization to Human Chromosome 1 of the Human Fast- twitch Skeletal Muscle Calsequestrin Gene.

Somat. Cell Mol. Genet. 16: 185-189 (1990)  (IF=0.835, CI=13)

 

13.      Alex E. MacKenzie, Robert G. Korneluk, Francesco Zorzato, Junichi Fujii, Michael Phillips, David Iles, Be Wieringa, Suzanne Leblond, Jane Bailly, Huntington F. Willard, Cathenine Duff, Ronald G. Worton, and David H. MacLennan

The Human Ryanodine Receptor Gene: Its Mapping to 19q13.1, Placement in a Chromosome 19 Linkage Group and Exclusion as the Gene Causing Myotonic Dystrophy.

Am. J. Hum. Genet. 46: 1082-1089 (1990)  (IF=10.426, CI=78)

 

14.      Junichi Fujii, Kei Maruyama, Michihiko Tada, and David H. MacLennan

Co-expression of Cardiac/slow-twitch Ca2+-ATPase (SERCA2) and Phospholamban.

FEBS Lett. 273: 232-234 (1990)  (IF=3.720, CI=35)

 

15.      Junichi Fujii, Angel Zarain-Herzberg, Huntington, F. Willard, Michihiko Tada, and David H. MacLennan 

Structure of the Rabbit Phospholamban Gene, Cloning of the Human cDNA and Assignment of the Gene to Human Chromosome 6.

J. Biol. Chem. 266: 11669-11675 (1991)  (IF=7.666, CI=44)

 

16.      Junichi Fujii, Kinya Otsu, Francesco Zorzato, Stella de Leon, Vijay K. Khanna, Janice E. Weiler, Peter J. O'Brien, and David H. MacLennan

Identification of a Mutation in Porcine Ryanodine Receptor Associated with Malignant Hyperthermia.

Science 253: 448-451 (1991)  (IF=24.595, CI=572)

 

17.      Elizabeth F. Gillard, Kinya Otsu, Junichi Fujii, Vijay K. Khanna, Stella de Leon, Jeanette Derdemezi, Beverley A. Britt, Catherine L. Duff, Ronald G. Worton, and David H. MacLennan

A Substitution of Cysteine for Arginine 614 in the Ryanodine Receptor is Potentially Causative of Human Malignant Hyperthermia.

Genomics 11: 751-755 (1991)  (IF=3.386, CI=190)

 

 

 

18.      Junichi Fujii and Naoyuki Taniguchi

Phorbol Ester Induces Manganese-superoxide Dismutase in Tumor Necrosis Factor-resistant Cells

J. Biol. Chem. 266: 23142-23146 (1991)  (IF=7.666, CI=78)

 

19.      Elizabeth F. Gillard, Kinya Otsu, Junichi Fujii, Catherine Duff, Stella de Leon,Vijay K. Khanna, Beverley A. Britt, Ronald G. Worton, and David H. MacLennan

Polymorphisms and Deduced Amino Acid Substitutions in the Coding Sequence of the Ryanodine Receptor (RYR1) Gene in Individuals with Malignant Hyperthermia.

Genomics 13: 1247-1254 (1992)  (IF=3.386, CI=109)

 

20.      Eiji Miyoshi, Junichi Fujii, Norio Hayashi, Keiji Ueda, Takehiro Towata, Hideyuki Fusamoto, Takenobu Kamada, and Naoyuki Taniguchi

Enhancement of Hepatitis B Surface Antigen Expression by 5-Azacytidine in a

Hepatitis B Virus-transfected Cell Line. 

Int. J. Cancer 52: 137-140 (1992)  (IF=3.545, CI=1)

 

21.      Toshiyuki Nakata, Keiichiro Suzuki, Junichi Fujii, Mutsuo Ishikawa, Haruyuki Tatsumi, Toru Sugiyama, Takashi Nishida, Tetsuya Shimizu, Michiaki Yakushiji, and Naoyuki Taniguchi

High Expression of Mn-superoxide Dismutase in 7,12-Dimethylbenz(a)anthracene-

induced Ovarian Cancer and Increased Serum Levels in the Tumor-bearing Rats

Carcinogenesis 13: 1941-1943 (1992)  (IF=4.118, CI=9)

 

22.      Yoshitaka Ikeda, Junichi Fujii, and Naoyuki Taniguchi.

Significance of Arg-107 and Glu-108 in the Catalytic Mechanism of Human g-Glutamyl Transpeptidase: Identification by Site-directed Mutagenesis

J. Biol. Chem. 268: 3980-3985 (1993)  (IF=7.666, CI=26)

 

23.      Motoko Takahashi, Junichi Fujii, Tadashi Teshima, Keiichiro Suzuki, Tetsuo Shiba, and Naoyuki Taniguchi

Identity of a Major 3-Deoxyglucosone Reducing Enzyme with Aldehyde Reductase in Rat Liver Established by Protein Sequencing and cDNA Expression

Gene 127: 249-253 (1993)  (IF=2.258, CI=45)

 

24.      Toshiyuki Nakata, Keiichiro Suzuki, Junichi Fujii, Mutsuo Ishikawa, and Naoyuki Taniguchi

Induction and Release of Manganese Superoxide Dismutase from Mitochondria from Human Umbilical Vein Endothelial Cells by Tumor Necrosis Factor-a and Interleukin-1a

Int. J. Cancer 55: 646-650 (1993)  (IF=3.545, CI=16)

 

25.      Eiji Miyoshi, Suresh K. Jain, Toshihiro Sugiyama, Junichi Fujii, Norio Hayashi,

Hideyuki Fusamoto, Takenobu Kamada, and Naoyuki Taniguchi

Expression of DNA Methyltransferase in LEC Rats during Hepatocarcinogenesis

Carcinogenesis 14: 603-605 (1993)  (IF=4.118, CI=11)

 

26.      Kinya Otsu, Junichi Fujii, Muthu Periasamy, Michael Difilippantonio, Madhvi Uppender, David C. Ward, and David H. MacLennan

Chromosome Mapping of Five Human Cardiac and Skeletal Muscle Sarcoplasmic   

Reticulum Protein Genes

Genomics 17: 507-509 (1993)  (IF=3.386, CI=46)

27.      Keiichiro Suzuki, Haruyuki Tatsumi, Shoji Satoh, Takao Senda, Toshiyuki Nakata, Junichi Fujii, and Naoyuki Taniguchi

Manganese-superoxide Dismutase in Endothelial Cells: Localization and Mechanism of Induction.

Am. J. Physiol. 265: H1173-H1178 (1993)  (IF=2.747, CI=42)

 

28.      Han Geuk Seo, Haruyuki Tatsumi, Junichi Fujii, Atsushi Nishikawa, Keiichiro Suzuki, Kenji Kangawa, and Naoyuki Taniguchi.

Nitric Oxide Synthase from Rat Colorectum: Purification, Peptide Sequencing, Partial PCR, and Immunohistochemistry 

J. Biochem. 115: 602-607 (1994)  (IF=2.191, CI=19)

 

29.      Junichi Fujii, Toshiyuki Nakata, Yoshitaka Ikeda, Eiji Miyoshi, and Naoyuki Taniguchi

Induction of Manganese Superoxide Dismutase mRNA by Okadaic Acid and Protein Synthesis Inhibitors.

Biochem. J. 301: 31-34 (1994)  (IF=4.349, CI=13)

 

30.      Ryoichi Nakano, Shuzo Sato, Takashi Inuzuka, Kenji Sakimura, Masayoshi Mishina, Hitoshi Takahashi, Fusahiro, Ikuta, Yoshiaki Honma, Junichi Fujii, Naoyuki Taniguchi, and Shoji Tsuji

A Novel Mutation in Cu/Zn Superoxide Dismutase Gene in a Japanese Familial Amyotrophic Lateral Sclerosis. 

Biochem. Biophys. Res. Commun. 200: 695-703 (1994)  (IF=3.161, CI=75)

 

31.      Yoshiro Kayanoki, Junichi Fujii, Keiichiro Suzuki, Sumio Kawata, Yuji Matsuzawa, and Naoyuki Taniguchi.

Suppression of Antioxidative Enzyme Expression by Transforming Growth Factor-b1 in Rat Hepatocytes.

J. Biol. Chem. 269: 15488-15492 (1994)  (IF=7.666, CI=99)

 

32.      Hideaki Kaneto, Junichi Fujii, Keiichiro Suzuki, Hiroshi Kasai, Ryuzo Kawamori, Takenobu Kamada, and Naoyuki Taniguchi.

DNA Cleavage Induced by Glycation of Cu,Zn-superoxide Dismutase.

Biochem. J. 304: 219-225 (1994)  (IF=4.349, CI=28)

 

33.      Makito Hirano, Junichi Fujii, Yoshitaka Nagai, Masanobu Sonobe, Koichi Okamoto, Heihachi Araki, Naoyuki Taniguchi, and Satoshi Ueno

A New Variant Cu/Zn Superoxide Dismutase (Val7Glu) Deduced from Lymphocyte mRNA Sequences from Japanese Patients with Familial Amyotrophic Lateral Screlosis. 

Biochem. Biophys. Res. Commun. 204: 572-577 (1994)  (IF=3.161, CI=40)

 

34.      Yoshitaka Ikeda, Junichi Fujii, Naoyuki Taniguchi, and Alton Meister.

Expression of an Active Glycosylated Human g-Glutamyl Transpeptidase Mutant

That Lacks a Membrane Anchor Domain.

Proc. Natl. Acad. Sci. USA. 92: 126-130 (1995)  (IF=10.260, CI=16)

 

35.      Motoko Takahashi, Lu Ya-bin, Theingi Myint, Junichi Fujii, Yoshinao Wada, and Naoyuki Taniguchi.

In Vivo Glycation of Aldehyde Reductase, a Major 3-Deoxyglucosone Reducing Enzyme: Identification of Glycation Sites. 

Biochemistry 34: 1433-1438 (1995)  (IF=4.493, CI=37)

 

36.      Junichi Fujii, Theingi Myint, Han Geuk Seo, Yoshiro Kayanoki, Yoshitaka Ikeda, and Naoyuki Taniguchi.

Characterization of Wild-type and Amyotrophic Lateral Sclerosis-related Mutant Cu,Zn-superoxide Dismutase Overprodued in Baculovirus-infected Insect Cells.

J. Neurochem. 64: 1456-1461 (1995)  (IF=4.906, CI=24)

 

37.      Han Geuk Seo, Junichi Fujii, Hidenobu Soejima, Norio Niikawa, and Naoyuki Taniguchi.

Heme Requirement for Production of Active Endothelial Nitric Oxide Synthase in

Baculovirus-infected Insect Cells.

Biochem. Biophys. Res. Commun. 208: 10-18 (1995)  (IF=3.161, CI=21)

 

38.      Terry K. Smith, Yoshitaka Ikeda, Junichi Fujii, Naoyuki Taniguchi, and Alton Meister. 

Different Sites of Acivicin Binding and Inactivation of g-Glutamyl Transpeptidase.

Proc. Natl. Acad. Sci. USA. 92: 2360-2364 (1995)  (IF=10.260, CI=21)

 

39.      Yoshitaka Ikeda, Junichi Fujii, Naoyuki Taniguchi, and Alton Meister. 

Human g-Glutamyl Transpeptidase Mutants Involving Conserved Aspartate Residues and the Unique Cysteine Residues of the Light Subunit.

J. Biol. Chem. 270: 12471-12475 (1995)  (IF=7.666, CI=19)

 

40.      Hideaki Kaneto, Junichi Fujii, Han Geuk Seo, Keiichiro Suzuki, Taka-aki Matsuoka, Masahiro Nakamura, Haruyuki Tatsumi, Yoshimitsu Yamasaki, Takenobu Kamada, and Naoyuki Taniguchi.

Apoptotic Cell Death Triggered by Nitric Oxide in Pancreatic b-cells.

Diabetes 44: 733-738 (1995)  (IF=9.019, CI=218)

 

41.      Michio Asahi, Junichi Fujii, Keiichiro Suzuki, Han Geuk Seo, Tsunehiko Kuzuya, Masatsugu Hori, Michihiko Tada, Shigeru Fujii, and  Naoyuki Taniguchi

Inactivation of Glutathione Peroxidase by Nitric Oxide: Implication for Cyototoxicity.

J. Biol. Chem. 270: 21035-21039 (1995)  (IF=7.666, CI=147)

 

42.      Yoshitaka Ikeda, Junichi Fujii, Mary E. Anderson, Naoyuki Taniguchi, and Alton Meister. 

Involvement of Ser-451 and Ser-452 in the Catalysis of Human g-Glutamyl Transpeptidase.

J. Biol. Chem. 270: 22223-22228 (1995)  (IF=7.666, CI=23)

 

43.      Motoko Takahashi, Junichi Fujii, Eiji Miyoshi, Ayumu Hoshi, and Naoyuki Taniguchi.

Elevation of Aldose Reductase Gene Expression in Rat Primary Hepatoma and Hepatoma Cell Lines: Implication in Detoxification of Cytotoxic Aldehydes. 

Int. J. Cancer 62: 749-754 (1995)  (IF=3.545, CI=29)

 

44.      Hiroyuki Saito, Jianguo Gu, Atsushi Nishikawa, Yoshito Ihara, Junichi Fujii, Yutaka Kohgo, and Naoyuki Taniguchi.

Organization of the Human N-Acetylglucosaminyltransferase V Gene.

Eur. J. Biochem. 233: 18-26 (1995)  (IF=3.307, CI=31)

 

 

 

 

45.      Han Geuk Seo, Ikuya Takata, Masahiro Nakamura, Haruyuki Tatsumi, Keiichiro Suzuki, Junichi Fujii, and Naoyuki Taniguchi

Induction of Nitric Oxide Synthase and Concomitant Suppression of Superoxide Dismutases in Experimental Colitis in Rats

Arch. Biochem. Biophys. 324: 41-47 (1995)  (IF=2.386, CI=51)

 

46.      Yilin Zhang, Junichi Fujii, Michael S. Phillips, Hai-Shiene Chen, George Karpati, Won-Chee Yee, Bertold Schrank, David R. Cornblath, Kevin B. Boylan, and David H. MacLennan.

Characterization of cDNA and Genomic DNA Encoding SERCA1, the Ca2+-ATPase of Human Fast-Twitch Skeletal Muscle Sarcoplasmic Reticulum, and Its Elimination as a Candidate Gene for Brody Disease

Genomics 30: 415-424 (1995)  (IF=3.386, CI=33)

 

47.      Han Geuk Seo, Noriko Fujiwara, Hideaki Kaneto, Michio Asahi, Junichi Fujii, and Naoyuki Taniguchi.

Effect of a Nitric Oxide Synthase Inhibitor, S-Ethylisothiourea, on Cultured Cells and Cardiovascular Functions of Normal and Lipopolysaccharide-treated Rabbits.

J. Biochem. 119: 553-558 (1996)  (IF=2.191, CI=5)

 

48.      Motoko Takahashi, Ayumu Hoshi, Junichi Fujii, Eiji Miyoshi, Takehiro Kasahara, Keiichiro Suzuki, Katsuyuki Aozasa, and Naoyuki Taniguchi. 

Induction of Aldose Reductase Gene Expression in LEC Rats during Development of the Hereditary Hepatitis and Hepatoma. 

Jpn. J. Cancer Res. 87: 337-341 (1996)  (IF=2.117, CI=17)

 

49.      Yoshiro Kayanoki, Junichi Fujii, Kazi Nazrul Islam, Keiichiro Suzuki, Sumio Kawata, Yuji Matsuzawa, and Naoyuki Taniguchi.

The Protective Role of Glutathione Peroxidase in Apoptosis Induced by Reactive Oxygen Species.   

J. Biochem. 119: 817-822 (1996)  (IF=2.191, CI=62)

 

50.      Yoshitaka Ikeda, Junichi Fujii, and Naoyuki Taniguchi. 

Effect of Substitutions of Conserved Histidine Residues in Human g-Glutamyl Transpeptidase.

J. Biochem. 119: 1166-1170 (1996)  (IF=2.191, CI=4)

 

51.      Ayumu Hoshi, Motoko Takahashi, Junichi Fujii, Theingi Myint, Hideaki Kaneto,  Keiichiro Suzuki, Yoshimitu Yamasaki, Takenobu Kamada, and Naoyuki Taniguchi.

Glycation and Inactivation of Sorbitol Dehydrogenase in Normal and Diabetic Rats. Biochem. J. 318: 119-123 (1996)  (IF=4.349, CI=19)

 

52.      Ryoichi Nakano, Takashi Inuzuka, Koki Kikugawa, Hitoshi Takahashi, Kenji Sakimura, Junichi Fujii, Naoyuki Taniguchi, and Shoji Tsuji

Instability of Mutant Cu/Zn Superoxide Disumutase (Ala4Thr) Associated with Familial Amyotrophic Lateral Sclerosis. 

Neurosci. Lett. 211: 129-131 (1996)  (IF=2.085, CI=11)

 

53.      Ayako Okado, Yoshimi Kawasaki, Yukiko Hasuike, Motoko Takahashi, Tadashi Teshima, Junichi Fujii, and Naoyuki Taniguchi

Induction of Apoptotic Cell Death by Methylglyoxal and 3-Deoxyglucosone in Macrophage-Derived Cell Lines. 

Biochem. Biophys. Res. Commun. 225: 219-224 (1996)  (IF=3.161, CI=57)

54.      Michael S. Phillips, Junichi Fujii, Vijay K. Khanna, Stella DeLeon, Kathy Yokobata, Pieter J. de Jong, and David H. MacLennan

The Structural Organization of the Human Skeletal Muscle Ryanodine Receptor (RYR1) Gene. 

Genomics 34: 24-41 (1996)  (IF=3.386, CI=67)

 

55.      Noriko Fujiwara, Ayako Okado, Han Geuk Seo, Junichi Fujii, Kigen Kondo, and Naoyuki Taniguchi

Quinazoline Derivatives Suppress Nitric Oxide Production by Macrophages through Inhibition of NOS II Gene Expression

FEBS Lett. 395:299-303 (1996)  (IF=3.720, CI=3)

 

56.      Hideaki Kaneto, Junichi Fujii, Theingi Myint, Kazi Nazrul Islam, Nobuko Miyazawa, Keiichiro Suzuki, Yoshimi Kawasaki, Masahiro Nakamura, Haruyuki Tatsumi, Yoshimitsu Yamasaki, and Naoyuki Taniguchi.

Reducing Sugar Triggers Oxidative Modification and Apoptosis in Pancreatic b-cells by Provoking Oxidative Stress through Glycation Reaction.

Biochem. J. 320: 855-863 (1996)  (IF=4.349, CI=67)

 

57.      Kazi Nazrul Islam, Yoshiro Kayanoki, Hideaki Kaneto, Keiichiro Suzuki, Michio Asahi, Junichi Fujii, and Naoyuki Taniguchi.

TGF-b Triggers Oxidative Modification and Enhances Apoptosis in HIT-cells through Accumulation of Reactive Oxygen Species by Suppression of Catalase and Glutathione Peroxidase. 

Free Radic. Biol. Med. 22: 1007-1017 (1997)  (IF=4.079, CI=34)

 

58.      Han Geuk Seo, Junichi Fujii, Michio Asahi, Ayako Okado, Noriko Fujiwara, and Naoyuki Taniguchi

Roles of Purine Nucleotides and Adenosine in Enhancing NOS II Gene Expression in Interleukin-1b-Stimulated Rat Vascular Smooth Muscle Cells. 

Free Radic. Res. 26: 409-418 (1997)  (IF=2.270, CI=6)

 

59.      Michio Asahi, Junichi Fujii, Toshifumi Takao, Tsunehiko Kuzuya, Masatsugu Hori, Yasutsugu Shimonishi, and Naoyuki Taniguchi

The Oxidation of Selenocysteine Is Involved in the Inactivation of Glutathione Peroxidase by Nitric Oxide Donor.

J. Biol. Chem. 272: 19152-19157 (1997)  (IF=7.666, CI=47)

 

60.      Takashi Fujikado, Yoshimi Kawasak, Junichi Fujii, Naoyuki Taniguchi, Masaki Okada, Atsushi Suzuki, Genjiro Ohmi, and Yasuo Tano

The effect of Nitric Oxide Synthase Inhibitor on form Deprivation Myopia.

Curr. Eye Res. 16: 992-996 (1997)  (IF=1.385, CI=11)

 

61.      Akio Matsumoto, Rikinari Hanayama, Masahiro Nakamura, Keiichiro Suzuki, Junichi Fujii, Haruyuki Tatsumi, and Naoyuki Taniguchi

A High Expression of Heme Oxygenase-1 in the Liver of LEC Rats at the Stage of Hepatitis; The Possible Implication of Induction in Uninvolved Tissues.

Free Radic. Res. 28:383-391 (1998)  (IF=2.270, CI=3)

 

62.      Masahiko Koizumi, Junichi Fujii, Keiichiro Suzuki, Takehiro Inoue, Toshihiko Inoue, John M. C. Gutteridge, and Naoyuki Taniguchi

A Marked Increase in Free Copper Levels in the Plasma and Liver of LEC Rats: An Animal Model of Wilson Disease and Liver Cancer

Free Radic. Res.28 :441-450 (1998)  (IF=2.270, CI=12)

63.      Junichi Fujii, Yoshitaka Ikeda, Toshiya Watanabe, Yoshimi Kawasaki, Keiichiro Suzuki, Chizuko Fujii, Motoko Takahashi, and Naoyuki Taniguchi

A Defect in the Mitochondrial Import of Mutant Mn-Superoxide Dismutase Produced in Sf21 Cells.

J. Biochem. 124: 340-346 (1998)  (IF=2.191, CI=0)

 

64.      Yutaka Hatanaka, Junichi Fujii, Tatsushi Fukutomi, Toshiya Watanabe, Wenyi Che, Yasuhiro Sanada, Yasuyuki Igarashi, and Naoyuki Taniguchi

Reactive Oxygen Species Enhances the Induction of Inducible Nitric Oxide Synthase by Sphingomyelinase in RAW264.7 Cells

Biochim. Biophys. Acta 1393: 203-210 (1998)  (IF=2.590, CI=12)

 

65.      Toshiya Watanabe, Junichi Fujii, Keiichiro Suzuki, Tsuneko Fujii, Michio Asahi, Ken Matsuoka, and Naoyuki Taniguchi

Dysfunction of Antioxidative Enzymes in the Trinitrobenzensulfonic Acid-induced Coliltis Rat

Pathophysiology 5: 191-198 (1998)

 

66.      Nobuko Miyazawa, Yoshimi Kawasaki, Junichi Fujii, Myint Theingi, Ayumu Hoshi, Rieko Hamaoka, Akio Matsumoto, Naofumi Uozumi, Tadashi Teshima, and Naoyuki Taniguchi

Immunological Detection of Fructated Proteins in In Vitro and In Vivo

Biochem. J. 336:101-107 (1998)  (IF=4.349, CI=5)

 

67.      Yoshimi Kawasaki, Junichi Fujii, Nobuko Miyazawa, Ayumu Hoshi, Ayako Okado, Yasuo Tano, and Naoyuki Taniguchi

Specific Detection of the Early process of the Glycation Reaction by Fructose and Glucose in Diabetic Rat Lens.

FEBS Lett. 441:116-120 (1998)  (IF=3.720, CI=9)

 

68.      Akio Matsumoto, Ayako Okado, Tsuneko Fujii, Junichi Fujii, Masayuki Egashira, Norio Niikawa, and Naoyuki Taniguchi.

Cloning of Peroxiredoxin Gene Family in Rats and Characterization of the Fouth Member. 

FEBS Lett. 443:246-250 (1999)  (IF=3.720, CI=38)

 

69.      Yukihiro Yamaguchi, Junichi Fujii, Shinya Inoue, Naofumi Uozumi, Shusaku Yanagidani, Yoshitaka Ikeda, Masayuki Egashira, Osamu Miyoshi, Norio Niikawa, and Naoyuki Taniguchi.

Mapping of the a1,6Fucosyltransferase Gene, FUT8, to Human Chromosome 14q24.3.

Cytogenet. Cell Genet. 84: 58-60 (1999)  (IF=1.604, CI=6)

 

70.      Junichi Fujii, Rieko Hamaoka, Akio Matsumoto, Tsuneko Fujii, Yukihiro Yamaguchi, Masayuki Egashira, Osamu Miyoshi, Norio Niikawa, and Naoyuki Taniguchi.

The Structural Organization of the Human Aldehyde Reductase Gene, AKR1A1, and Mapping to Chromosome 1p32-p33.

Cytogenet. Cell Genet. 84: 230-232 (1999)  (IF=1.604, CI=1)

 

 

 

 

 

71.      Makoto Hasegawa, Yuki Kawano, Yoshiko Matsumoto, Yuji Hidaka, Junichi Fujii, Naouyuki Taniguchi, Akihiro Wada, Toshiya Hirayama, and Yasutsugu Shimonishi.

Expression and Characterization of the Extracellular Domain of Guanylyl Cyclase C from a Baculovirus and Sf21 Insect Cells.

Protein Expr. Purif. 15: 271-281 (1999)  (IF=1.416, CI=6)

 

72.      Rieko Hamaoka, Yuji Yaginuma, Tomoaki Takahashi, Junichi Fujii, Masahiko Koizumi, Han Geuk Seo, Yutaka Hatanaka, Kaoru Hashizume, Kunio Ii, Toshiaki Hanafusa, Yuji Matsuzawa, Mutsuo Ishikawa, and Naoyuki Taniguchi

Different Expression Patterns of Nitric Oxide Synthase Isozymes in Various Gynecological Cancers

J. Cancer Res. Clin. Oncol. 125: 321-326 (1999)  (IF=1.052, CI=3)

 

73.      Noriko Fujiwara, Tsuneko Fujii, Junichi Fujii, and Naoyuki Taniguchi.

Functional Expression of Rat Thioredoxin Reductase: Selenocysteine Insertion Sequence Element Is Essential for the Active Enzyme. 

Biochem. J. 340: 439-444 (1999)  (IF=4.349, CI=24)

 

74.      Rieko Hamaoka, Junichi Fujii, Jun-ichiro Miyagawa, Motoko Takahashi, Michihiko Kishimoto, Makoto Moriwaki, Koji Yamamoto, Yoshitaka Kajimoto, Yoshimitsu Yamasaki, Toshiaki Hanafusa, Yuji Matsuzawa, and Naoyuki Taniguchi.

Overexpression of the Aldose Reductase Gene Induces Apoptosis in Pancreatic b-Cells by Causing Redox Imbalance.

J. Biochem. 126: 41-47 (1999)  (IF=2.191, CI=10)

 

75.      Vladimir V. Shuvaev, Junichi Fujii, Yoshimi Kawasaki, Hidehiko Itoh, Rieko Hamaoka, Anne Barbier, Olivier Ziegler, Gerard Siest, and Naoyuki Taniguchi

Glycation of Apolipoprotein E Impairs Its Binding to Heparin. Identification of the Major Glycation Site

Biochim. Biophys. Acta 1454: 296-308 (1999)  (IF=2.590, CI=12)

 

76.      Seiji Kikuchi, Akihiko Ogata, Kazuyoshi Shinpo, Fumio Moriwaka, Junichi Fujii, Naoyuki Taniguchi, and Kunio Tashiro

Detection of an Amadori product, 1-hexitol-lysine, in the anterior horn of the amyotrophic lateral sclerosis and spinobulbar muscular atrophy spinal cord:  Evidence for early involvement of glycation in motoneuron diseases.

Acta Neuropathol. 99: 63-66 (2000)  (IF=2.402, CI=4)

 

77.      Hideaki Miwa, Junichi Fujii, Hiroyuki Kanno, Naoyuki Taniguchi, and Katsuyuki Aozasa

Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated apoptosis.

Free Radic. Res. 33: 45-56 (2000)  (IF=2.270, CI=8)

 

78.      Ayako Okado-Matsumoto, Theingi Myint, Junichi Fujii, and Naoyuki Taniguchi.

Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation.

Free Radic. Res. 33: 65-73 (2000)  (IF=2.270, CI=13)

 

 

 

 

79.      Ayako Okado-Matsumoto, Akio Matsumoto, Junichi Fujii, and Naoyuki Taniguchi.

Peroxiredoxin IV is a secretable protein with heparin-binding properties under reduced conditions.

J. Biochem.127: 493-501 (2000)  (IF=2.191, CI=28)

 

80.      Yukihiro Yamaguchi, Yoshitaka Ikeda, Tomoaki Takahashi, Hideyuki Ihara, Tatsuya Tanaka, Junichi Fujii, and Naoyuki Taniguchi.

Genomic structure and promoter analysis of the human a1,6fucosyltransferase gene (FUT8)

Glycobiology 10: 637-643 (2000)  (IF=3.728, CI=7)

 

81.      Tsuneko Fujii, Rieko Hamaoka, Junichi Fujii, and Naoyuki Taniguchi.

Redox capacity of cells affects inactivation of glutathione reductase by nitrosative stress.

Arch. Biochem. Biophys.378: 123-130 (2000)  (IF=2.386, CI=9)

 

82.      Takeshi Endo, Tsuneko Fujii, Kenzo Sato, Naoyuki Taniguchi, and Junichi Fujii.

A pivotal role of Zn-binding residues in the function of the copper chaperone for SOD1.

Biochem. Biphys. Res. Commun.276: 999-1004 (2000)  (IF=3.161, CI=1)

 

83.      Ayako Okado-Matsumoto, Akio Matsumoto, Junichi Fujii, and Naoyuki Taniguchi. Effect of cAMP on inducible nitric oxide synthase gene expression; Its dual and cell specific functions.

Antioxid. Redox Signal. 2: 631-642 (2000) (IF=3.037, CI=1)

 

84.      Tsuneko Fujii, Junichi Fujii, and Naoyuki Taniguchi.

Augmented expression of peroxiredoxinVI in rat lung and kidney after birth implies an antioxidative role.

Eur. J. Biochem. 268:218-224 (2001)  (IF=3.307, CI=15)

 

85.      Vladimir V. Shuvaev, Isabelle Laffont, Jean-Marie Serot, Junichi Fujii, Naoyuki Taniguchi, and Gerard Siest.

Increased protein glycation in cerebrospinal fluid of Alzheimer's disease.

Neurobiol. Aging 22:397-402 (2001)  (IF=3.399, CI=13)

 

86.      Noriko Fujiwara, Tsuneko Fujii, Junichi Fujii, and Naoyuki Taniguchi.

Roles of N-terminal active cysteines and C-terminal cysteine-selenocysteine in the catalytic mechanism of mammalian thioredoxin reductase.

J. Biochem. 129: 803-812 (2001)  (IF=2.191, CI=5)

 

87.      Isoji Sasagawa, Shingo Matsuki, Yasuhiro Suzuki, Yoshihito Iuchi, Kazuo Tohya, Michio Kimura, Teruhiro Nakada, and Junichi Fujii

Possible involvement of the membrane-bound form of peroxiredoxin 4 in acrosome formation during spermiogenesis of rats

Eur. J. Biochem. 268: 3053-3061 (2001)  (IF=3.307, CI=7)

 

88.      Yoshihito Iuchi, Takashi Kobayashi, Tomoko Kaneko, Masatoshi Takahara, Toshihiko Ogino, and Junichi Fujii.

The expression of a Y-box protein, YB2/RYB-a, precedes protamine 2 during spermatogenesis in rodents.

Mol. Human Reprod. 7: 1023-1031 (2001)  (IF=3.643, CI=5)


 

89.      Tomoko Kaneko, Yoshihito Iuchi, Satoshi Kawachiya, Tsuneko Fujii, Hidekazu Saito, Hirohisa Kurachi, and Junichi Fujii.

Alteration of glutathione reductase expression in the female reproductive organs during the estrous cycle. 

Biol. Reprod. 65: 1410-1416 (2001)  (IF=3.417, CI=8)

 

90.      Tsuneko Fujii, Keiji Mori, Yoshinori Takahashi, Naoyuki Taniguchi, Akira Tonosaki, Hidetoshi Yamashita, and Junichi Fujii.

Multilocal expression and developmental changes in the levels of glutathione reductase in ocular tissues of rats.

Histochem. J. 33: 267-272 (2001)  (IF=1.161, CI=3)

 

91.      Rudy J. Castellani, Peggy L. Harris, Lawrence M. Sayre, Junichi Fujii, Naoyuki Taniguchi, Michael P. Vitek, Hank Founds, Craig S. Atwood, George Perry, and Mark A. Smith.

Active glycation in neurofibrillary pathology of Alzheimer disease: Ne-(carboxymethyl) lysine and hexitol-lysine.

Free Radic. Biol. Med. 31: 175-180 (2001)  (IF=4.079, CI=13)

                                             (以後 IF2000年版)

92.      Tsuneko Fujii, Takeshi Endo, Junichi Fujii, and Naoyuki Taniguchi.

Differential epression of glutathione reductase and cytosolic glutathione peroxidase, GPX1, in developing rat lungs and kidneys.

Free Radic. Res. 36: 1041-1049 (2002)  (IF=2.735, CI=3)

 

93.      Michiharu Miura, Isoji Sasagawa, Yasuhiro Suzuki, Teruhiro Nakada, and Junichi Fujii.

Apoptosis and expression of apoptosis-related genes in mouse testis following heat exposure.

Fertil. Steril. 77: 787-793 (2002)  (IF=2.960, CI=9)

 

94.      Shingo Matsuki, Isoji Sasagawa, Yoshihito Iuchi, and Junichi Fujii.

Impaired expression of peroxiredoxin 4 in damaged testes by artificial cryptorchidism

Redox Rep. 7:276-278 (2002)  (IF=1.045, CI=1)

 

95.      Tomoko Kaneko, Yoshihito Iuchi, Takashi Kobayashi, Tsuneko Fujii, Hidekazu Saito, Hirohisa Kurachi, and Junichi Fujii.

Expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis.

Eur. J. Biochem. 269: 1570-1578. (2002)  (IF=2.849, CI=5)

 

96.      Takashi Kobayashi, Tomoko Kaneko, Yoshihito Iuchi, Shingo Matsuki, Motoko Takahashi, Isoji Sasagawa, Teruhiro Nakada, and Junichi Fujii

Localization and physiological implication of aldose reductase and sorbitol dehydrogenase in male reproductive systems, qccessory glands, and spermatozoa of rats

J. Androl. 23: 674-683 (2002)  (IF=2.128, CI=4)

    (以後IF2001年版)

97.      Yoshihito Iuchi, Tomoko Kaneko, Shingo Matsuki, Isoji Sasagawa, and Junichi Fujii.

Concerted changes in the YB2/RYB-a protein and protamine 2 mRNA in the mouse testis under Heat Stress.

Biol. Reprod. 68: 129-135 (2003)  (IF=3.508, CI=1)

 

98.      Rina Takamiya, Motoko Takahashi, Theingi Myint, Yong Seek Park, Nobuko Miyazawa, Takeshi Endo, Noriko Fujiwara, Haruhiko Sakiyama, Yoshiko Misonou, Yasuhide Miyamoto, Junichi Fujii, and Naoyuki Taniguchi.

Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis

FASEB J. 17:938-940 (2003) published Mar 5, 2003, 10.1096/fj.02-0768fje  (IF=8.817, CI=   )

 

99.      Tsuneko Fujii, Yoshitaka Ikeda, Hidetoshi Yamashita, and Junichi Fujii..

Transient elevation of glutathione peroxidase 1 around the time of eyelid opening in the neonatal rat.

J. Ocul. Pharmacol. Ther. 19:361-370 (2003) (IF=1.085, CI=  )

 

100. Tomoko Kaneko, Yoshihito Iuchi, Motoko Takahashi, and Junichi Fujii. Colocalization of polyol-metabolizing enzymes and immunological detection of fructated proteins in the female reproductive system of the rat.

Histochem. Cell Biol. 119:309-315 (2003) (IF=2.477, CI=1) DOI 10.1007/s00418-003-0516-5

 

101.Shingo Matsuki, Yoshihito Iuchi, Yoshitaka Ikeda, Isoji Sasagawa, Yoshihiko Tomita, and Junichi Fujii

Suppression of cytochrome c release and apoptosis in testes with heat stress by minocycline.

Biochem. Biophys. Res. Commun. 312: 843-849 (2003)  (IF=3.055, CI=  )

 

102.Kaoru Otsu, Yoshitaka Ikeda, and Junichi Fujii.

The accumulation of Mn-superoxide dismutase under metal-depleted conditions: An implicated role of zinc ion for cellular redox balance

Biochem. J. 377: 241-248 (2004)  (IF=4.326, CI=  )

DOI (Digital Object Identifier): 10.1042/BJ20030935

 

103.Yoshihito Iuchi, Tomoko Kaneko, Shingo Matsuki, Tatsuya Ishii, Yoshitaka Ikeda, Koji Uchida, and Junichi Fujii.

Carbonyl stress and detoxification ability in the male genital tract and testis of rats. Histochem. Cell Biol. 121:123-130 (2004)  (IF=2.477, CI=  )

 

104.Kaname Uno, Yoshihito Iuchi, Junichi Fujii, Hideaki Sugata, Katsunori Iijima, Katuaki Kato, Tooru Shimosegawa, and Testuhiko Yoshimura.

In vivo study on cross-talk between inducible nitric oxide synthase and cyclooxygenase in rat gastric mucosa: Effect of COX activity on NO production.

J. Pharmacol. Exp. Ther. 309:995-1002 (2004)  (IF=3.555, CI=    )

 

105.Yuki Nagaoka, Yoshihito Iuchi, Yoshitaka Ikeda, and Junichi Fujii.

Glutathione reductase is expressed at high levels in pancreatic islet cells

Redox Rep. (2004) in press  (IF=1.045, CI=  )

 

106.Guang Cheng, Yoshitaka Ikeda, Yoshihito Iuchi, and Junichi Fujii.

Detection of S-glutathionylated proteins by glutathione S-transferase overlay.

Arch. Biochem. Biophys. in press (2004)  (IF=2.386, CI=  )

 


Junichi FUJII---Reviews and Proceedings--    December 10, 2004

 

1. Michihiko Tada, Masaaki Kadoma, and Junichi Fujii

    Phospholamban, a Regulatory Factor of Ca Pump from Cardiac Sarcoplasmic

    Reticulum. 

    in "Cardiac Function under Ischemic and Hypoxia" (K. Yamada, A.M.

    Katz, and J. Toyama eds.) The University of Nagoya Press, Nagoya, Japan, pp89-99

    (1986)

 

2. Atsuko Uyeda, Katsuhiko Kitano, Junichi, Fujii, Masaaki Kadoma, Michihiko Tada,

    and Shoji Tanaka 

    in "14th Symposium on Nucleic Acids Chemistry"  pp121-124 (1986)

 

3. Michihiko Tada, Masaaki Kadoma, and Junichi Fujii 

    Cyclic AMP Regulation of Ca Pump from Cardiac Sarcoplasmic Reticulum.

    in "Perspectives of Biological Energy Transduction" (Y. Mukohata, M. F.

    Morales, S. Fleisher eds.) Academic Press, New York, pp199-206 (1987)

 

4. Michihiko Tada, Masaaki Kadoma, and Junichi Fujii

    Protein Phosphorylation in Cardiac Sarcoplasmic Reticulum and Its Functional 

    Consequences.

    in "Heart Function and Metabolism" (N.S. Dhalla, G.N. Pierc, R.E. Beamish

    eds.) Martinus Nijhoff Publishing, Boston, pp255-266 (1987)

 

5. Michihiko Tada, Masaaki Kadoma, and Junichi Fujii

    Regulation of Cardiac Sarcoplasmic Reticulum Ca Pump by the cAMP-

    phospholamban System.

    in "Ca Channel Blockers and the Heart" (S.D. Seth, S.C. Manchanda, H. H.

    Siddiqui eds.), Interprint, New Delhi, India, pp57-70 (1987)

 

6. Michihiko Tada, Masaaki Kadoma, Makoto Inui, and Junichi Fujii

    Regulation of Ca Pump from Heart Sarcoplasmic Reticulum.

    Methods Enz. 157: 107-154 (1988)  (IF=4.068, CI=70)

 

7. Michihiko Tada, Masaaki Kadoma, Junichi Fujii

    Molecular Structure of Canine Cardiac Phospholamban, the Regulatory Protein of Ca

    Pump ATPase of Sarcoplasmic Reticulum.

    in "Cell Calcium Metabolism: Physiology, Biochemistry, Pharmacology,

   and Clinical Applications" (G. Fiskum ed.)  Plenum Press, New York,

    pp93-101 (1988)

 

8. Micihiko Tada, Masaaki Kadoma, Junihchi Fujii, Yoshihiro Kimura, and Yoshiyuki       

    Kijima  

    Molecular Structure and Function of Phospholamban: The Regulatory Protein of

    Calcium Pump in Cardiac Sarcoplasmic Reticulum.

    in "Calcium Protein Signaling; Adavances in Experimental Medicine and

   Biology" Vol. 255 (H. Hidaka ed.) Plenum Press, New York, pp79-89 (1988)

 

9. Michihiko Tada, Masaaki Kadoma, Makoto Inui, Junichi Fujii, Yoshihiro Kimura,          

    Yoshiyuki Kijima, and Tatsuya Sasaki

    Molecular Structure and Function of Phospholamban: The Regulatory Protein of

    Calcium Pump in Cardiac Sarcoplasmic Reticulum.

    in "Bioinformatics:  Information Transduction and Processing Systems   

   from Cell to Whole Body" (O. Hatase, and J. H. Wang eds.) Elsevier, pp73-82 (1988)

 

 

 

10. Kei Maruyama, David M. Clarke, Junichi Fujii, Tip W. Loo, and David H. MacLennan

      Expression and Mutation of Ca2+-ATPase of the Sarcoplasmic Reticulum.

      Cell Motil. Cytoskel. 14: 26-34 (1989)  (IF=2.772, CI=16)

 

11. Naoyuki Taniguchi, Mutsuo Ishikawa, Tetsuo Kawaguchi, Junichi Fujii, Keiichiro     

      Suzuki, and Toshiyuki Nakata

      Expression of Mn-superoxide Dismutase in Carcinogenesis.

      Tohoku J. Exp. Med. 168: pp105-111 (1992)  (IF=0.409, CI=3)

 

12. David H. MacLennan, Kinya Otsu, Junichi Fujii, Francesco Zorzato, Michael S.

      Phillips, Peter O'brien, Alan L. Archibald, Beverley A. Britt, Elizabeth F. Gillard,

      and Ronald G. Worton

      The Role of the Skeletal Muscle Ryanodine Receptor Gene in Malignant

      Hyperthermia.

      Symp. Soc. Exp. Biol. 46: 189-201 (1992) 

      

13. J. Fujii, Y. Ikeda, K. Suzuki, and N. Taniguchi

      Characterization of Human Mn-SOD and Cu,Zn-SOD Expressed in  

      Baculovirus/insect Cells System

      in "Frontiers of Reactive Oxygen Species in Biology and Medicine"

      (K. Asada, and T. Yoshikawa eds) p251-254 (1994)

 

14. H. Kaneto, T. Ookawara, J. Fujii, K. Suzuki, and N. Taniguchi.

      in "Frontiers of Reactive Oxygen Species in Biology and Medicine"

      (K. Asada, and T. Yoshikawa eds) pp169-170 (1994)

 

15. J. Fujii, Y. Kayanoki, K. Suzuki, and N. Taniguchi

      Regulation of Human Mn-SOD Gene Expression by Cytokines and Other Factors

      in "Frontiers of Reactive Oxygen Species in Biology and Medicine"

      (K. Asada, and T. Yoshikawa eds) pp269-270 (1994)

 

16. Y. Kayanoki, J. Fujii, K. Suzuki, Y. Aida, T. Uchikoshi, S. Kawata, Y.

      Matsuzawa, and N. Taniguchi.

      in "Frontiers of Reactive Oxygen Species in Biology and Medicine"

      (K. Asada, and T. Yoshikawa eds) pp295-296 (1994)

 

17. Suzuki, H. Tatusmi, S. Satoh, T. Senda, T. Nakata, J. Fujii, and N. Taniguchi.

      in "Frontiers of Reactive Oxygen Species in Biology and Medicine"

      (K. Asada, and T. Yoshikawa eds)  pp297-298 (1994)

 

18. H. Ohno, K. Suzuki, J. Fujii, H. Yamashita, T. Kizaki, S. Oh-ishi, and N.

      Taniguchi

      Superoxide Dismutase in Exercise and Disease.

      in "Exercise and Oxygen Toxicity" (C. K. Sen, L. Packer, and O.

      Hanninen eds) pp127-161 (1994)

 

19. Junichi Fujii,  Han Geuk Seo, Michio Asahi, and Naoyuki Taniguchi

       ADP Enhances NOS II Gene Expression in Rat Smooth Muscle Cells Stimulated

       with Interleukin-1

       in "The Biologoly of Nitric Oxide, Part 5" (S. Moncada, J. Stamler, S.

       Gross, and E. A. Higgs eds) pp50 (1995)

 

20.  Michio Asahi, Junichi Fujii,  Han Geuk Seo,  and Naoyuki Taniguchi

       Inactivation of Glutathione Peroxidase by Nitric Oxide: Implication for

       Cytotoxicity.

       in "The Biologoly of Nitric Oxide, Part 5" (S. Moncada, J. Stamler, S.

       Gross, and E. A. Higgs eds) pp115 (1995)

21. Hideaki Kaneto, Junichi Fujii, Han Geuk Seo, Keiichiro Suzuki, Masahiro

       Nakamura, Haruyuki Tatsumi, and Naoyuki Taniguchi

       Apoptosis Induced by Nitric Oxide in Pancreatic b-Cells.

       in "The Biologoly of Nitric Oxide, Part 5" (S. Moncada, J. Stamler, S.

       Gross, and E. A. Higgs eds) pp132 (1995)

 

22. Motoko Takahashi, Junichi Fujii, Tadashi Teshima, Keiichiro Suzuki, Tetsuo Shiba,

      and Naoyuki Taniguchi

      Glycation and Inactivation of Rat Aldehyde Reductase, a Major 3-Deoxyglucosone

      Reducing Enzyme.

      in "Maillard Reaction in Chemistry, Food, and Health" (T. P. Labuza, G.

      A. Reineccius, V. M. Monnier, J. O'Brien, and J. W. Baynes eds) pp427 (1995)

 

23. Naoyuki Taniguchi, Hideaki Kaneto, Michio Asahi, Motoko Takahashi, Shigeki

       Higashiyama, Junichi Fujii, Keiichiro Suzuki, and Yoshiro Kayanoki

       Involvement of Glycation and Oxidative Stress in Diabetic Macroangiopathy

       Diabetes, 45: S81-S83 (1996)   (IF=9.019)  (CI=34)

 

24. Junichi Fujii, Theingi Myint, Ayako Okado, Hideaki Kaneto, and Naoyuki Taniguchi

       Oxidative Stress Caused by Glycation of Cu,Zn-Superoxide Dismutase and Its

       Effects on Intracellular Components.

       Nephrol. Dial. Transpl. 11(Suppl 5): 34-40 (1996)   (IF=1.752)  (CI=12)

 

25. Eiji Miyoshi, Junichi Fujii, Norio Hayashi, and Naoyuki Taniguchi

            LEC Rats: An Overview of Recent Findings.

            J. Trace Elem. Exp. Med. 10: 135-145 (1997)   (IF=0.574)  (CI=6)

 

26. Naoyuki Taniguchi, Junichi Fujii, Hideaki Kaneto, Michio Asahi, Theingi Myint,

            Nobuko Miyazawa, Keiichiro Suzuki, and Kazi Nazrul Isam

            Glycation as Oxidative Stress and Redox Regulation: Implications for Aging,

        Diabetes, and Familial Amyotrophic Lateral Sclerosis.

            in "Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases"

            (L. Montagnier, R. Olivier, and C. Pasquier eds.), Marcel Dekker, New York,             pp497-502 (1998)

 

27. Junichi Fujii, Michio Asahi, Ayako Okado, and Naoyuki Taniguchi.

            Dysfunction of Redox Regulation: A Common Mechanism for Apoptotic Cell

        Death by Nitric Oxide and the Glycation Reaction.

            in "Pathophysiology of Lipid Peroxides and Related Free Radicals"

            (K. Yagi ed.) pp125-134 (1998) Japan Scientific Societies Press, Tokyo

 

28. H. Kaneto, J. Fujii, M. Theingi, N. Miyazawa, K.N. Islam, Y. Kawasaki, K.             Suzuki, and

      Naoyuki Taniguchi, .

      Reducing Sugars Induce Apoptosis in Pancreatic b-Cells by Provoking Oxidative

      Stress via a Glycation Reaction.  

      in "The Maillard Reaction in Foods and Medicine" (J. O'Brien, H. E.             Nursten,

      M.J.C. Crabbe, J. M. Ames eds) pp345-350 (1998) Royal Society of Chemistry in

      Cambridge, London

 

29. J. Fujii, N. Miyazawa, Y. Kawasaki, M. Theingi, A. Hoshi, and N. Taniguchi.

      Production of an antibody against fructated proteins and its usefulness to detect in

      vitro and in vivo fructation.

      in "The Maillard Reaction in Foods and Medicine" (J. O'Brien, H. E.             Nursten,

      M.J.C. Crabbe, J. M. Ames eds) pp408 (1998) Royal Society of Chemistry in

      Cambridge, London

    


30. A. Matsumoto, A. Okado, J. Fujii, and N. Taniguchi

Coordinated Induction of Heme Oxygenase and NO Synthase-II in cAMP Dependent Mechanism

in "The Biology of Nitric Oxide, Part 6" (S. Moncada, N. Toda, H. Maeda, and E.A. Higgs eds) Portland Press, London, 268 (1998)

 

31. J. Fujii, M. Asahi, T. Takao, Y. Shimonishi, and N. Taniguchi

            NO-dependent Oxidation of Selenocysteine in the Active Center of Glutathione             Peroxidase Is Responsible for Its Inactivation

in "The Biology of Nitric Oxide, Part 6" (S. Moncada, N. Toda, H. Maeda, and E.A. Higgs eds) Portland Press, London, 35 (1998)

 

32. Y. Kawasaki, T. Fujikado, J. Fujii, Y. Tano, and N. Taniguchi

            Nw-Nitro-L-Arginine Methylester Inhibits Experimental Myopia

in "The Biology of Nitric Oxide, Part 6" (S. Moncada, N. Toda, H. Maeda, and E.A. Higgs eds) Portland Press, London, 112 (1998)

 

33. R. Hamaoka, J. Fujii, M. Koizumi, Y. Hatanaka, K. Ii, Y. Yaginuma, M. Ishikawa, and N.

Taniguchi

            Frequent Expression of Nitric Oxide Synthase Isozymes in Gynecological Cancer

in "The Biology of Nitric Oxide, Part 6" (S. Moncada, N. Toda, H. Maeda, and E.A. Higgs eds) Portland Press, London, 190 (1998)

 

34. A. Okado, A. Matsumoto, J. Fujii, and N. Taniguchi

Induction of NOS II Gene by cAMP Is not Mediated by a Typical CRE in Macrophages and Smooth Muscle Cells

in "The Biology of Nitric Oxide, Part 6"(S. Moncada, N. Toda, H. Maeda, and E.A. Higgs eds) Portland Press, London, 236 (1998)

 

35. Junichi Fujii and Naoyuki Taniguchi.

            Dysfunction of Redox System by Reactive Oxygen and Nitrogen Species.

            in "Redox Regulation of Cell Signaling and Its Clinical Applications"

            (J. Yodoi and L. Packer eds), Marcel Dekker, Basel, 11-24 (1999)

 

36. Junichi Fujii

            Chapter 5.  Catalytic Protein-Enzymes

            in "Medical Biochemistry" (M. H. Dominiczak and J. W. Baynes eds.)

            Mosby, London, 43-54 (1999)

 

37. Junichi Fujii, Motoko Takahashi, Rieko Hamaoka, Yoshimi Kawasaki, Nobuko 

Miyazawa, and Naoyuki Taniguchi

Physiological Relevance of Aldehyde Reductase and Aldose Reductase Gene Expression. Adv. Exp. Med. Biol. (Weiner, H., Maser, E., Crabb, D.W., and Lindahl, R. eds), Academic/Plenum Publishers, New York, 463: 419-426 (1999)    (IF=0.446)  (CI=1)

 

38. Junichi Fujii, and Naoyuki Taniguchi

Down Regulation of Superoxide Dismutases and Glutathione Peroxidase by Reactive Oxygen and Nitrogen Species

Free Radic. Res.  31: 301-308 (1999)   (IF=2.270)  (CI=10)

 

39. K. Suzuki, H. Ohno, S. Oh-ishi, T. Kizaki, T. Ookawara, J. Fujii, Z. Radak, and N.

Taniguchi.

Superoxide Dismutases in Exercise and Disease.

in "Handbook of Oxidants and Antioxidants in Exercise" (C.K. Sen, L. Packer, and O. Hanninen eds.), Elsevier Science, Amsterdam, 243-295 (2000)

 

40. J. Fujii. 6. NO-generating system.

in "Experimental Protocols for Reactive Oxygen

and Nitrogen Species" (N. Taniguchi and  J.M.C. Gutteridge Eds), Oxiford Press, 25-27 (2000) 

 

41. J. Fujii. 27. Nitric oxide synthase (NOS) activity assay: RI method to detect L-citrulline.

in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxiford Press, 101-102 (2000)

 

42. J. Fujii. 28. Nitric oxide synthase (NOS) activity assay: determination of produced

NADP+.

in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxiford Press, 103-105 (2000)

 

43. J. Fujii. 6. Detection of nitric oxide synthase (NOS) expression: preparation of RNA.

in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxiford Press, 194-196 (2000)

 

44. S. Kikuchi, K. Shinpo, J. Fujii, Z. Makita, M. Takeuchi, N. Taniguchi, and K. Tashiro.

Abnormal Glycation in ALS.

in "Molecular Mechanism and Therapeutics of Amyotrophic Lateral Sclerosis" (K. Abe, Ed), Elsevier, 255-263 (2001)     

 

45. Junichi Fujii, Tomoko Kaneko, Takashi Kobayashi, Yoshihito Iuchi, Motoko Takahashi.  Localization and Physioloigcal Implication of Polyol-Metabolyzing Enzymes in Male and Female Reproductive Systems of Rat

In "The Maillard Reaction in Food Chemistry and Medical Science: Update for the Postgenomic Era" (S. Horiuchi, T. Kurata, N. Taniguchi, T. Osawa, F. Hayase, Eds), Amsterdam, Elsevier, 363-364 (2002)

 

46. Junichi Fujii, Yoshitaka Ikeda. Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein.

Redox Rep. 7: 123-130 (2002)  (IF=0.717)  (CI=18)

 

47. J. Fujii, T. Kaneko, Y. Iuchi. Glutathione Redox Status in the Rat Reproductive System.

In “XI Biennial Meeting of the Society for Free Radical Research International” (C.Pasquier ed), Bologna, Monduzzi Editore, C716: 217-220 (2002)

 

48. Junichi Fujii, Yoshihito Iuchi, Shingo Matsuki, Tatsuya Ishii. Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues

Asian J. Androl. 5:231-242 (2003)  (IF=0.8271.064)  (CI=3)

 

49. Junichi Fujii

Chapter 5.  Catalytic Protein-Enzymes

in "Medical Biochemistry 2nd ed" (M. H. Dominiczak and J. W. Baynes eds.)

Mosby, London, in press (2004)

 

50. J. Fujii, K. Otsu, Y. Ikeda, S. Sato, Y. Ohba. Elucidation of Singlet Oxygen-Induced Cell Death. In "Proceeding of XII Biennial Meeting of SFRR", Monduzzi Editore, in press (2004)

 

 


Society Membership and Scientific Activity:

 

1982                                Japanese Biochemical Society

(boardman since 1999)

1984                Japanese Biophysical Society

1990                Japanese Molecular Biological Society

1992                Japanese Cancer Association

1999                American Society for Biochemistry and Molecular Biology, U.S.A.

1999                                The Oxygen Society (A constituent member of the International Society for Free Radical Research)

(Since 2002, the name changed to:)

Society for Free Radical Biology and Medicine, U.S.A.

2000                                NO Society of Japan

(boardman since 2000)

2001                Societies for Free Radical Research, Japan

(boardman since 2001)

2002                Paper Reporters, Reproductive Biology and Endocrinology

2003                Society for the Study of Reproduction, U.S.A.

2003                                Japanese Society of Lipid Peroxide and Free Radical Research

(boardman since 2003)

 

Research Interests: 

 

1. Research directed at roles of reactive oxygen and reactive nitrogen species in  

  physiology and pathophysiology. 

            2. Redox regulation of mammalian reproduction

            3. Causes and mechanism of diabetic complication and aging

 

Bibliography:  On separate files.