Will M. Lee
Professor
Department of Zoology, The University of Hong Kong,
Pokfulam Road, Hong Kong
Tel: 2299-0800
Fax: 2559-9114
E-mail:hrszlwm@hku.hk

Current Position:
Professor
Department of Zoology, The University of Hong Kong,
Pokfulam Road, Hong Kong Tel: 2299-0800, Fax: 2559-9114, E-mail:hrszlwm@hku.hk

Education:
B.Sc. University of Wisconsin, U.S.A.

M.Phil. The Chinese University of Hong Kong

Ph.D. The University of Hong Kong

Academic Appointments :
1984-1986 Research Fellow, Population Council, Rockefeller University, New York, U.S.A.
1986-1987 Research Scientist, Genentech, Inc., South San Francisco, U.S.A.
1988-1994 Lecturer, Department of Zoology, The University of Hong Kong
1990-1990 Visiting Scientist, London Regional Cancer Centre, Ontario,Canada
1994-1999 Senior Lecturer (Associate Professor), Department of Zoology, University of Hong Kong
1999- Professor, Department of Zoology, University of Hong Kong
2000- Head, Department of Zoology, University of Hong Kong

Recent Journal Publications:

1. Cheng CK, Cheung CH and Lee WM (2003) Mouse Testin: complementary DNA cloning, genomic organization, and characterization of its proximal promoter region. Biology of Reproduction 68:1376-1386.

2. Siu MKY, Lee WM and Cheng CY (2003) The interplay of collagen IV, tumor necrosis factor-a, gelatinase B (Matrix Metalloprotease-9), and tissue inhibitor of metalloprotease-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis. Endocrinology 144:371-387.

3. Lui WY, Mruk D, Lee WM and Cheng CY (2003) Sertoli cell tight junction dynamics: their regulation and spermatogenesis. Biology of Reproduction 68:1087-1097.

4. Lui WY, Lee WM and Cheng CY (2003) Transforming growth factor-b3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway. Biology of Reproduction 68:1597-1612.

5. Siu MKY, Mruk D, Lee WM and Cheng CY (2003) Adhering junction dynamics in the testis are regulated by an interplay of b1-integrin and the focal adhesion complex (FAC)-associated proteins. Endocrinology 144:2141-2163.

6. Lui WY, Mruk D, Lee WM and Cheng CY (2003) Adherens junctions (AJ) dynamics in the testis and spermatogenesis. Journal of Andrology 24:1-14.

7. Lui WY, Lee WM and Cheng CY (2003) TGF-bs: their role in testicular function and Sertoli cell tight junction dynamics. International Journal of Andrology 26:147-160.

8. Lui WY, Lee WM and Cheng CY (2003) Rho GTPases and spermatogenesis. Biochim Biophys Acta 1593:121-129.

9. Lui WY, Lee WM and Cheng CY (2003) Sertoli-Germ Cell Adherens Junction Dynamics in the Testis Are Regulated by RhoB GTPase via the ROCK/LIMK Signaling Pathway Biology of Reproduction 68:2189-2206.

10. Lee YL, Lee KF, Xu JS, Kwok KL, Luk JM, Lee WM and Yeung WSB (2003) Embryotrophic factor-3 from human oviductal cells affects the messenger ribonucleic acid expression of mouse blastocyst. Biology of Reproduction 68:375-382.

11. Lee NPY, Mruk D, Lee WM and Cheng CY (2003) Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis? Biology of Reproduction 68:489-508.

12. Yao YQ, Xu JS, Lee WM, Yeung WS and Lee KF (2003) Identification of mRNAs that are up-regulated after fertilization in the murine zygote by suppression subtractive hybridization. Biochem Biophys Res Comm. 304:60-66.

13. Chen Y-m, Lee NPY, Mruk DD, Lee WM, and Cheng CY (2003) Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study. Biology of Reproduction 69:656-672.

14. Wong CCS and Lee WM (2002) Proximal cis-acting elements Sp1, Sp3 and E2F regulate the mouse Mer gene transcription in Sertoli cells. European Journal of Biochemistry 269:3789-3800.