Current
Address: Monash Institute of Reproduction
and Development,
27-31
Wright St.,
Clayton
3168. Australia.
Telephone: 61
3 9594 7127
Fax:
61 3 9594 7111
e.mail:
moira.obryan@med.monash.edu.au
Citizenship: Australian
Employment & Education:
¡¤
2001 - present: NH&MRC R.D. Wright Fellow and Senior
Scientist.
Monash Institute of
Reproduction and Development (MIRD), Monash University, 27-31 Wright St.,
Clayton 3168.
¡¤
2000 (Aug) ¨C 2001: Senior Scientist and NH&MRC Senior
Research Officer.
Monash Institute of
Reproduction and Development (MIRD), Monash University, 27-31 Wright St.,
Clayton 3168.
¡¤
2000 (Jan.) ¨C 2000 (Aug): NH&MRC Senior Research Officer
Monash Institute of
Reproduction and Development (MIRD), Monash University, 27-31 Wright St.,
Clayton 3168.
¡¤ 1996 ¨C 2000: Peter
Doherty Postdoctoral Fellowship (NH&MRC #967135).
Monash Institute of Reproduction and Development
(IRD), 27-31 Wright St., Clayton 3168.
Australia.
¡¤
1993-1995: Post-doctoral Research Fellow.
The Population Council, Center for Biomedical
Research, 1230 York Ave., New York, N.Y.
10021. U.S.A.
¡¤
1990-1993: Ph.D. (Medicine), The University of
Melbourne, awarded April 1994.
Supervisors: Drs. B.F.
Murphy1 and H.W.G. Baker2. 1The Department of Nephology, St Vincent¡¯s
Hospital, Victoria Pde., Fitzroy, 3065 and 2The Department of
Obstetrics and Gynaecology, The Royal Women¡¯s Hospital, Grattan St., Carlton,
3053. Australia. Dissertation title: Clusterin in the male reproductive
tract and in cell death - awarded April 1994.
¡¤
1988: Bachelor of Science with first class honours - pathology.
The University of Melbourne,
Parkville, 3052. Australia.
¡¤
1985-1987: Bachelor of Science.
The University of Melbourne,
Parkville, 3052. Australia.
Awards and Distinctions:
2004: ¡®Best Project¡¯ award from The Rebecca Cooper Medical Research
Foundation. Co-held with Gerard Gibbs (post-doc in my group).
2004: Monash University Research Fund Travel Award ($1000)
2001-2004: NHMRC R.D. Wright Career Development Award. Award
#143781.
2001: Monash University Research Fund Travel Award ($1000).
2001: Australian Academy of Science, Career Development Award, Presented
at the Australian Academy of Science ¨C Science at the Shine Dome Symposium, May
2001.
1999: European
Society for Reproduction and Endocrinology ¨C Fertility Society of Australian
Young Scientist lecture, Tour, France, July.
1998: Best Presentation by a Young Scientist, The Fertility Society of
Australia. Presented at the annual meeting in Hobart, October.
1997: Serono Post-graduate
Travel Award, Endocrine Society of Australia.
1997: Junior Scientist Nomination, Australian Society for Reproductive
Biology - unable to compete due to family illness.
1996-2000: NHMRC Peter Doherty Post-doctoral Fellowship. Award #967135.
1996-1998: ARC Australian Post-doctoral Fellowship ¨C never activated due to
concurrent NHMRC Fellowship.
1993-1995: Mellon Foundation Post-doctoral Fellowship to work at The Population
Council Centre for Biomedical Research, Rockefeller University, New York.
1994: Ph.D. (Medicine), The University of Melbourne. Australia.
1990-1993: Australian Post-graduate
Research Award, The Commonwealth Government of Australia.
1985-1988: Bachelor of Science with first class honours. The
University of Melbourne.
Australia.
1985-1987: Donovan
Faculty Scholarship - Newman College, The University of Melbourne.
Grants and research contracts:
2005-2006: Andrology Australia (The Australian Centre of Excellence in Male
Reproductive Health). National DNA repository for the identification of genetic
causes of male infertility. CIs:
Moira O¡¯Bryan and Rob McLachlan. $75,000 per annum.
2005-2010: NHMRC Program Grant. CIs: David de Kretser, Gail Risbridger,
Milton Hearn, Graham Jenkin, Mark Hedger, Euan Wallace, Kate Loveland, David
Phillips, Moira O¡¯Bryan. ~$1.56M/year. Award #334011.
2004-2008: NHMRC Enabling Grant. ¡®The Australian Phenome Bank¡¯. Chief
investigators: Chris Goodnow, David de Kretser, Moira O'Bryan. $300K per year
for 5 years. Award #268084.
2004: NHMRC
Large Equipment Grant for a gel documentation system. CIs: Loveland, Moran,
O¡¯Bryan et al $61,200.
2004: Rebecca
Cooper Medical Research Foundation. Identificaton of genes essential for
male fertility ¨C equipment grant. CIs: Gerard Gibbs, Moira O¡¯Bryan. $15,000. Prize
for highest ranking application
2003-2005: Schering AG research contract to identify novel contraceptive
targets and mechanisms and regulators of prostate disease. CIs: David de Kretser, Evan Simpson, Gail
Risbridger, Rob McLachlan, Moira O'Bryan, Lisa O¡¯Donnell. €600,000 per year.
2003: NHMRC
Large Equipment Grant for a denaturing high performance liquid
chromatography system. CIs: Moira O¡¯Bryan, David de Kretser, David Cram, Rob
McLachlan, Colin Clyne, Ed Stanley, Peter Fuller, Andrew Elefanty, Vincent
Harley, Evan Simpson and Andrew Perkins. $71,000.
2003-2007: The Australian Research Council, Centre for Excellence.
$9,458,900. Biotechnology and Development. CIs: John Aitken (Director), David
de Kretser, Gary Hime, Michael Holland, David Jans, Peter Koopman, Kate
Loveland, Eileen McLaughlin, Moira O¡¯Bryan, Andrew Sinclair, Sean Roman. Award
#CE0348239.
2003: Monash
University. $20,000. A proteomic analysis of the rat sperm tail. CI: Moira
O¡¯Bryan, Co-investigator: Gerard Gibbs.
2002: Monash
IVF. The Genetics of Male infertility. $48,000. CIs Moira O'Bryan, David
Cram, David de Kretser and Rob McLachlan.
2001-2004: Andrology Australia (The Australian Centre of Excellence in
Male Reproductive Health). National DNA repository for the identification of
genetic causes of male infertility. CI:
Moira O¡¯Bryan. Co-investigator:
David de Kretser. $267,602.
2001: NHMRC Equipment Grant for a high performance liquid chromatography
system. CIs: Drs David de Kretser, David Phillips,
Mark Hedger, Kate Loveland, Moira O¡¯Bryan, John Morrison, Gail Risbridger,
Martin Pera, Paul Hertzog.
$86,000.
2001-2006: NHMRC
program grant ¡®Reproductive Processes¡¯. Award #143786. CIs: Drs. David
de Kretser, Milton Hearn, Mark Hedger, Graham Jenkin, Kate Loveland, John
Morrison, Moira O¡¯Bryan, David Phillips and Gail Risbridger. $1.7M / year.
2001: Rebecca Cooper Medical Research Foundation. The genetics of male
infertility ¨C gene discovery and mutation detection. $10,000.
1999: Monash IVF Research Grant, Monash
IVF, Victoria CIs David Cram, Moira O'Bryan, David de Kretser and Rob McLachlan
$28,000.
Community Service,
Committees:
2005: Deputy convener. ASMR National Scientific Conference. Couran
Cove, QLD. November, 2005.
2004: Program organizing committee. Inaugural mammalian phenomics
workshop, November 18-20, 2004, The Australian National University, Canberra.
2003-present: National
Director, The Australian Society of Medical Research.
2002-3: Convener,
The Victorian branch of the Australian Society for Medical Research ¡®Medical
Research Week¡¯, 2003
2002-3: Convener,
The Victorian branch of the Australian Society for Medical Research ¡®Medical
Research Week¡¯, 2003
2002: Organization
committee, Australian Health and Medical Research Congress 2002 (AHMRC
2002) 25-29 November 2002 in Melbourne
2002: Post-graduate
course work degrees committee, Monash University.
2001-2002: Secretary,
The Victorian branch of The Australian Society for Medical Research.
2001: Convener, The Prince Henry¡¯s Institute of
Medical Research and Monash Institute of Reproduction and Development joint
symposium on ¡°Reproductive Genomics¡±, December 5-6, 2001. Monash Medical Centre, Clayton 3168.
2001: The subject of a documentary made by The Australian Academy of
Science.
This documentary consisted of a half hour interview about my life and science
towards the purpose of attracting secondary school students to continue science
at University. The project was funded by the ARC and videos will eventually be
distributed to every secondary school in Australia.
1999-present: Committee
member, The Victorian branch of The Australian Society for Medical
Research.
1999-present: Post-graduate
students committee ¨C Monash Institute of Reproduction and Development.
1999-2000: Mentor,
Masters of Reproductive Biology Masters Programme, Monash University.
1999-2001: Mentor,
Department of Neurosciences, Monash University.
1999-2002: Deputy
Radiation Safety Office, Monash Institute of Reproduction and Development.
1997-2001: Senior
honours year examiner, Department of Anatomy, Monash University.
1996-1998: Radiation
Safety Officer, Monash Institute of Reproduction and Development.
Editorial
Boards
2004-present: The Biology of
Reproduction (Official journal of the American Society for the Study of Reproduction).
Executive positions:
2004-present: The access and
advisory committee, The Australian Phenome Bank, The Australian Phenomics
Facility, Canberra.
2003-present: National
Director, The Australian Society of Medical Research.
2001-present: Male
infertility advisory group, Andrology Australia (The Centre for Excellence in
Men¡¯s Reproductive Health).
University appointments
2004: Assessment Panel for the Strategic Grant Scheme, Monash University
2001: Monash University
Post-graduate students course work committee
Teaching:
2004-presents: BMS3011 male reproductive
biology lectures.
1997-present: Guest lecturer, 3rd
year anatomy, Department of Anatomy, Monash University.
BSc honours students: 8
Graduate student
supervision:
PhD students
Orapin Gerdprasert (BScVetSci),
co-supervisor. Completed April 2002. Scholarship: Thai Government. Thesis
title: Cellular and cytokine responses to inflammation in the rat testis.
Current Position Assistant Professor, Faculty of Medicine, Khon-Kaen University,
Thailand.
Deborah Hickox BSc(U. Melb)
BSc(Hons)(Monash): Main supervisor. Completed October 2003. Scholarship: APA.
Thesis title: The yeast two hybrid analysis of tpx-1 binding partners. Currently working as a post-doctoral
Fellow in my group before going overseas for a post-doctoral position.
*2001 Monash IRD student prize
for Best Student Ph.D. presentation.
Claire Kennedy BSc(Hons)(Monash): Main
supervisor. Enrolled March 2001. Scholarship: APA.
*2002 Monash University prize
for post-graduate research.
*2003 Monash IRD student prize
for Best Student Ph.D. presentation.
*2004 ASA Lalor Foundation Travel
Award ¨C to attend the ASA meeting, Baltimore, April.
Leanne Cotton BSc(Monash) BSc(Hons)(U.
Melb.): Main supervisor. Enrolled March 2001. Scholarship: Monash University.
*2004 ASA Travel Award ¨C to attend
the ASA meeting in Baltimore, April.
Dean Whelan BAppS (Hons)(Swinburne
U.I.T.): Main supervisor. Enrolled March, 2003. Scholarship: Monash University.
Luke Swain BSc(Hons)(Monash): Main
supervisor. Will start March 2004. Scholarship: APA.
Society Membership:
The Endocrine Society of Australia
The Australian Society of Medical Research
The Australian Society for Reproductive Biology
Andrology Society of America
Invited speaker:
1997: Hormones
and Men¡¯s Health. Prince Henry¡¯s
Institute of Medical Research in conjunction with the Institute of Reproduction
and Development, Monash University.
Sperm tail proteins and motility.
Melbourne, Australia, February 1997.
1998: The
Australian Society for Medical Research.
The Emerging Genetic Basis for Male Infertility - Sperm tail proteins
and motility. Hobart, Australia,
November 1998.
1999: 15th
Annual Meeting of the European Society of Human Reproduction and Embryology
FSA/ESHRE exchange lecture - Tpx-1 in the testis and sperm function. Tours, France, June 1999.
2000: Department
of Anatomy and Cell Biology, Queen¡¯s University, Kingston, Ontario, Canada,
July.
2001: Secondary
Teachers Association of Victoria annual conference. Glen Waverly Secondary
College. June.
2003: Department
of Anatomy and Cell Biology, The University of Melbourne. The outer dense
fibres of the sperm tail. Function and fertility. October.
2004: School
of Biological Sciences, Monash University. Mouse and human approaches to a
greater understanding of male fertility, May.
2004: Major
National Research Facilities Road Show. Walter and Elisa Hall Institute,
Parkville, October. ¡®How to crack the nut of male infertility¡¯
2004: Prince
Henry¡¯s Institute of Medical Research. ¡®Of snakes and sperm: CRISP proteins¡¯
December.
2005: The Inaugural Mammalian Phenomics Symposium, The Australian National
University, Canberra. February.
Publications:
M1.
Murphy B.F., Saunders J.R., O¡¯Bryan M.K., Kirszbaum
L., Walker I.D., d¡¯Apice A.J.F., 1989.
SP-40,40 is an inhibitor of C5b-6-initiated haemolysis. Int. Immunol. 1: 551-554.
M2.
O¡¯Bryan M.K., Baker H.W.G., Saunders J.R., Kirszbaum L., Walker I.D.,
Hudson P., Liu D.Y., Glew M.D., d¡¯Apice A.J.F., Murphy B.F., 1990. Human seminal clusterin
(SP-40,40). Isolation and
characterization. J. Clin. Invest.
85L 1477-1486.
M3.
Pearse M.J., O¡¯Bryan M., Fisicaro N., Murphy B., and d¡¯Apice
A.J., 1992. Differential expression of clusterin in inducible models of
apoptosis. Int. Immunol. 4: 1225-1231.
M4.
O¡¯Bryan M.K., Cheema S.S., Bartlett P.F., Murphy B.F., and Pearse M.J.,
1992. Clusterin levels increase
during neuronal development. J.
Neurobiol. 24: 421-432.
M5.
Polihronis M., Machet D., Saunders J., O¡¯Bryan M., McRae J., and
Murphy B., 1992.
Immunohistological detection of C5b-9 complement complexes in normal and
pathological human livers.
Pathology 25: 20-23.
M6.
O¡¯Bryan M.K., Mallidis C., Murphy B.F., and Baker H.W.G., 1994. The immunohistological localization of
clusterin in the male genital tract in humans and marmosets. Biol. Reprod. 50: 502-509.
M7.
O¡¯Bryan M.K.., Murphy B.F., Liu D.Y., Clarke G.N., and Baker H.W.G.,
1994. The use of anticlusterin
monoclonal antibodies for the combined assessment of human sperm morphology and
acrosome integrity. Human Reprod.
9: 1490-1496.
M8.
Zini A., O¡¯Bryan M.K., Magid M.S., and Schlegel P.N., 1996. The immunohistochemical localization of
endothelial nitric oxide synthase in testis, epididymis and vas suggests a
possible role for nitric oxide in spermatogenesis and sperm maturation. Biol. Reprod. 55: 935-941.
M9.
O¡¯Bryan M.K., and Cheng C.Y., 1997. Purification and localization of testicular b2-microglobulin. Life Sciences 61: 487-494.
M10.
Mathur P.P., Grima J., Mo M.M., Zhu L.J., Arvindan G.R., Calcagno K., O¡¯Bryan
M., Chung S., Mruk D., Lee W.M., Silvestrini B., and Cheng C.Y., 1997. Differential expression of multiple
cathepsin mRNAs in the rat testis during development, maturation and following
lonidamine induced tissue restructuring.
Biochemistry and Molecular Biology International 42: 217-233.
M11.
O¡¯Bryan M.K., Grima J., Zini A., and Cheng C.Y., 1997. Haptoglobin is a Sertoli cell product
in the rat seminiferous epithelium:
its purification and regulation. J. Androl. 18: 637-645.
M12.
Thomas T.Z., Wang H., Niclasen P., O¡¯Bryan M.K., Evans L.W.,
Groome N., Pederson J., and Risbridger G.P., 1997. Expression and localization of activin and follistatins in
tissues from men with high grade prostate cancer. J. Clin. Endocrinology
Metabolism 82: 3851-3858.
M13.
Zini A., O¡¯Bryan M.K., Israel L., and Schlegel P.N.,
1998. Human sperm NADH and NADPH
diaphorase cytochemistry:
correlation with sperm motility.
Urology 51: 464-468.
M14.
Meinhardt A., O¡¯Bryan M.K., McFarlane J.R., Loveland
K.L., Mallidis C., Foulds L.M., Phillips D.J., and de Kretser D.M., 1998. Localization of follistatin in the rat
testis. J. Reprod. Fert. 112: 233-241.
M15.
O¡¯Bryan M.K., Loveland K.A., Herszfeld D., McFarlane J.F., Hearn M.T.W.,
and de Kretser D.M., 1998.
Identification of a rat testis-specific gene encoding a putative rat
outer dense fibre protein. Mol.
Reprod. Dev. 50: 313-322.
M16.
O¡¯Bryan M.K., Zini A., Cheng C.Y., and Schlegel P.N., 1998. Human sperm endothelial nitric oxide
synthase expression: correlation
with motility. Fert. Steril.
70: 1143-147.
M17.
Meinhardt M., Bacher M., O¡¯Bryan M.K., McFarlane J.R., Mallidis
C., Lehmann C., Metz C.N., de Kretser D.M., Bucala R., and Hedger M.P.,
1999. A switch in the cellular
localization of macrophage migration inhibitory factor in the rat testis after
ethane dimethane sulfonate treatment.
J. Cell Sci. 112:
1337-1344.
M18.
Kim Y.H., McFarlane J.R., O¡¯Bryan M.K., Almahbobi G.,
Temple-Smith P.D., and de Kretser D.M., 1999. Isolation and partial characterization of rat outer dense
fibres and comparison with rabbit and human spermatozoa using a polyclonal
antiserum. J. Reprod. Fert.
116: 345-353.
M19.
O¡¯Bryan M.K., Schlatt S., Phillips D.J., de Kretser D.M., and Hedger
M.P., 2000. Bacterial lipopolysaccharide-induced inflammation compromises
testicular function at multiple levels.
Endocrinology 141: 238-246.
M20.
Buzzard J.J., Morrison J.R., O¡¯Bryan M.K., Song Q., and Wreford N.G.,
2000. The developmental expression
of thyroid hormone receptors in the rat testis. Evidence for a novel thyroid hormone receptor transcript. Biol. Reprod. 62: 664-669.
M21.
Meehan T., Schlatt S., O¡¯Bryan M.K., de Kretser D.M., and Lakoski
Loveland, 2000. Regulation of
Sertoli and germ cell development by activin and FSH. Dev. Biol., 220: 225-237.
M22.
O¡¯Bryan M.K., Sebire S.L., Gerdprasert O., Hedger M.P., Hearn M.T.W.,
and de Kretser D.M., 2000. Cloning
and regulation of the rat activin bE subunit. J. Mol. Endo. 24: 409-418.
M23.
O¡¯Bryan M.K., Schlatt S., Gerdprasert G., Phillips D.J., de Kretser
D.M., and Hedger M.P., 2000.
Inducible nitric oxide synthase in normal testis function and in
inflammation-induced infertility. Biol. Reprod. 63: 1285-1293.
M24.
Gow R.M., O¡¯Bryan M.K., Canny B.J., Ooi G.T., and Hedger M.P.,
2001. Dexamethazone ameliorates
the inhibitory effects of lipopolysaccharide on luteinizing hormone secretion
and testicular steroidogenesis, but does not prevent testicular inflammation in
the male rat. J. Endo.168:
193-201.
M25.
O¡¯Bryan M.K., Sebire K.L., Meinhardt A., Edgar K.A., Keah H.-H., Hearn
M.T.W., and de Kretser D.M., 2001.
Tpx-1 is a component of the outer dense fibers and acrosome of rat
spermatozoa. Mol. Reprod. Dev., 58:
116-125.
M26.
Keah H.-H., O¡¯Bryan M.K., de Kretser D.M., and Hearn M.T.W.,
2001. Synthesis and application of
peptide immunogens related to the sperm tail protein tpx-1, a member of the
CRISP superfamily of proteins. J.
Pept. Res., 57: 1-10.
M27.
Zini A., O¡¯Bryan M.K., and Schlegel P.N., 2001. Nitric oxide synthase activity in human
seminal plasma. Urology 58: 85-89.
M28.
Dickins R.A., Frew I.J., House C.M., O¡¯Bryan M.K., Holloway A.J.,
Haviv I., Traficant N., de Kretser D.M., and Bowtell D.D.L., 2002. Meiosis I chromosome segregation in
male mice requires the RING domain ubiquitin ligase component Siah1a. Mol. Cell Biol., 22:2294-303.
M29.
Gerdprasert O., O¡¯Bryan M.K., Nikolic-Paterson D., Sebire K., de
Kretser D.M., and Hedger M.P., 2002.
Expression of monocyte chemoattractant protein-1 (MCP-1) and macrophage
colony-stimulating factor (M-CSF) in the rat testis: possible roles in monocyte recruitment. Mol. Hum. Reprod. 8: 518-524..
M30.
Gerdprasert O., O¡¯Bryan M.K., Muir J.A., Caldwell
A.M., Schlatt S., de Kretser D.M., and Hedger M.P., 2002. The response of testicular leukocytes
to lipopolysaccharide-induced inflammation: evidence for functional
heterogeneity of the testicular macrophage population. Cell Tissue
Research, 308: 277-285.
M31.
McManamny P., Chy H.S., Finkelstein D.H., Craythorn R.G., Crack P.J.,
Kola I., Cheema S.S., Horne M.K., Wreford N., O¡¯Bryan M.K., de Kretser
D.M., and Morrison J.R., 2002. A mouse model of spinal and bulbar muscular
atrophy. Hum. Mol. Genet. 11:
2103-2111
M32.
Hickox D., Gibbs G., Morrison J.R., Sebire K., Edgar K., Keah H.-H.,
Alter K., Loveland K.A., Hearn M.T.W., de Kretser D.M., and O¡¯Bryan M.K.,
2002. Identification of a novel
testis-specific member of the phosphatidylethanolamine binding protein family,
pebp-2. Biol Reprod 67: 917-927.
M33.
Kennedy C., Sebire K., de Kretser D.M. and O¡¯Bryan M.K. 2003.
Human sperm associated antigen-4 (SPAG-4) is a cancer/testis antigen.
Cell Tissue Res. 315(2):279-83. Epub 2003 Nov 12.
M35.
Gold E.J., O¡¯Bryan M.K., Mellor S.L., Cranfield M., Risbridger
G., Groome P., and Flemming J.S., 2004. bC-activin shows cell-specific
expression in rat ovary, testis, pituitary, uterus and adrenal, as well as in
rat liver. Mol Cell Endocrinol. 2004 Jul 30;222(1-2):61-9.
M36.
Douglas G.C., O¡¯Bryan M.K., Hedger M.P., Lee D., Yarski M.A.,
Smith A.I., and Lew R.A., 2004. The novel angiotensin converting enzyme
homologue, ACE2, is selectively expressed in mature Leydig cells of the testis.
Endocrinology, 145(10): 4703-11. Published on line ahead of print July 1, 2004.
M38.
Krebs DL, Metcalf D, Merson TD, Voss AK, Thomas T, Zhang
J-G, Rakar S, O¡¯Bryan MK, Wilson TA, Winey E, Mielke L, Nicola NA,
Hilton DJ, Alexander WS, 2004. Hydrocephalus in mice lacking Socs7. Proc Natl
Acad Sci U S A. 2004 Oct 19 [Epub ahead of print]
M39.
Webster K., O¡¯Bryan M.K., Aapola U., Lyle R., Meachem S.,
Antonarakis S, Hedger M., Peterson P, de Kretser D, and Scott HS. 2004. Meiotic
and epigenetic modification defects in Dnmt3L knockout mouse
spermatogenesis. Submitted for publication. *Equal First Author (Aug.
Proc. Natl. Acad. Sci. USA)
Reviews in refereed journals
R1.
de Kretser D.M., Meinhardt A., Meehan T., Phillips D.J., O¡¯Bryan M.K.,
and Loveland K.A, 2000. The role
of inhibin and related peptides on gonadal function. Mol. Cell. Endocrinol. 61:43-46.
R2.
de Kretser D.M., O¡¯Bryan M.K., Cram D., and McLachlan R.I.,
2000. Expanding our understanding
of spermatogenesis: the future
genetic test for infertility. Int. J. Andrology 23 (Suppl.): 30-33.
R3.
de Kretser D.M., Loveland K.L., Meehan T., O¡¯Bryan M.K., and
Wreford N.G., 2001. Inhibins,
activins and follistatin: actions
on the testis. Mol. Cell.
Endocrinol. 180: 87-92.
R4.
Cram D.S., O¡¯Bryan M.K., and de Kretser D.M., 2001. Male infertility genetics ¨C the
future. J. Androl. 22: 738-746.
R5.
Gibbs G. and O¡¯Bryan M.K., 2002. Joint Prince Henry¡¯s Institute
of Medical Research and Monash Institute of Reproduction and Development
Symposium ¨C Reproductive Genomics. Comparative & Functional Genomics
3: 205-208.
R6.
Cram D, Lynch M, O¡¯Bryan M., Salvado C., McLachlan R. and de
Kretser D, 2004. Genetic screening of infertile men. Reprod. Fertility,
Development, 16: 573-580.
Commentaries and other publications
Aitken
R.J., Baker M.A., and O¡¯Bryan M.K. 2004. Shedding light on
chemiluminescence. The application of chemiluminescence in diagnostic
andrology. J Androl. 2004 Jul-Aug;25(4):455-65.
Chapters in books (by invitation)
B1.
de Kretser
DM, Meehan T., O¡¯Bryan M.K., Wreford N.G., McLachlan R.I., and Loveland
K.L. Regulatory mechanism in
mammalian spermatogenesis. In
¡®Testis, epididymis and technologies in the year 2000¡¯. Jegou, Pineau and Siaz (Editors),
Springer, 2000. pp. 87-106.
B2.
de Kretser, O¡¯Bryan M.K., Cram D.S., and McLachlan R.I., 2004.
Genetics of male infertility: clinical applications. In press.
B3.
de Kretser D.M., Loveland K., O¡¯Bryan
M.K. and Kerr J. ¡®The Cytology of the
Testis and Intrinsic Control Mechanisms¡¯ in ¡®The Physiology of Reproduction,
Third Edition. Submitted for publication
International Patent Application:
P1.
A cell regulation factor, and uses thereof. Holders: M.K.
O¡¯Bryan, D.M. Hickox, M.T.W. Hearn, D.M de Kretser. Patent Number:
PCT/AU00/01177. Filing
date: September 22, 2000.
P2.
A sperm polypeptide: M.K. O¡¯Bryan, D.M. Hickox and D.M. de Kretser. Patent Number: PS1604. Filing date:
April 8, 2002. PCT.
Conference papers: 94
Granting bodies Reviewed for\
NHMRC
ARC
Telethon
(Italy)
Monash
University