Bo Yang

 

Nationality: Chinese

 

Contact: (Mailing Address, Email, Tel, Fax)：YanAn Rd. 353#, Dept。of  Pharmacology and Toxicology, School of Pharmaceutical Science, Zhejiang University, Hangzhou, China310031

 

Main research interest and the fields (branches) of articles you wish to review:

Relative to cancer research.

 

Publications:

l         Yang Bo and Reynolds CP: Tirapazamine cytotoxicity for neuroblastoma is p53- dependent.  Clinical Cancer Res 2005; in press.

l         Yang Bo, Keshelava N, Anderson CP, Reynolds CP: Antagonism of buthionine sulfoximine cytotoxicity for human neuroblastoma cell lines by hypoxia is reversed by the bioreductive agent tirapazamine.  Cancer Research 2003; 63:1520

l         Goto H, Yang Bo, Kohn D, et al:  Transduction of green fluorescence protein increases oxidative stress and sensitivity to cytotoxic drugs in neuroblastoma cell lines.  Molecular Cancer Therapeutics, 2003; 2:911

l         He QJ, Yang Bo, Wang WF, et al: Synergistic effects of DL111-IT in combination with mifepristone and misoprostol on termination of early pregnancy in preclinical studies. Contraception. 2003 ; 68 :289-95.

·         Qian Li-hui, Yang Bo, Leng Y, Cao L and Gu ZP. Inhibitory effect of nomegesterol acetate on the steroidogenesis of cultured granulosa cells from rat ovary in vitro. Acta Pharmacologica Sinica .2001; 22: 40

·         Yang Bo, Zhou H, He Q, Fang R. Termination of early pregnancy in the mouse, rat and hamster with DL111-IT and RU486. Contraception. 2000; 62:211

·         He Q, Ying Y, Yang Bo and Fang R. Synergistic effects of DL111-IT combined with mifepristone on termination of early pregnancy in rhesus monkeys. Contraception. 2000: 62:189.

·         Yang Bo, Cao L, Fang RY and Gu ZP. Luteolytic effects of DL111-IT in pregnant rats. European Journal of Pharmacology. 1999;380 : 145

·         Yang Bo, Cao L and Gu ZP. Effects of DL111-IT on decidua, PGs ocntents and uterine contractility in pregnant rats. Acta Pharmaceutica Sinica. 2000;135:641

·         Leng Y, Yang Bo, Cao L and Gu ZP. Effect of four kinds of antifertility agents on cultured rat luteal cells apoptosis. Acta Pharmacologica Sinica 1999;20:400

·         Yang Bo, Cao L Fang RY and Gu ZP. Luteolytic effect of DL111-IT in pseudopregnant rats. Acta Pharmaceutica Sinica 1999; 34:321

·         Yang Bo, Cao L, Fang RY and Gu ZP. Effect of DL111-IT on progesterone biosynthesis and viability of rat luteal cells in vitro. Acta Pharmacologica Sinica 1997;18:367

·         Yang Bo, Cao L and Sun ZX, et al. The effects of gossypol on rat cells, human decidual cells and cytotrophoblasts. Acta Pharmaceutica Sinica 1997;32:573

·         Chen Yong, Cao L and Yang Bo, et al., The effect of gossypol and misoprostol on luteal and decidual cells in vitro. Reproduction & Contraception 1997;8:8

·         Yang Bo, Fang RY. Synergistic effects on pregnancy-termination activity of DL111-IT in combinaiton with mifepristone. Acta Pharmacologica Sinica 1996;17:361

 

International Conference:  

92nd American Association for Cancer Research, March 24-28, 2001, New Orleans, LA, USA

93rd American Association for Cancer Research, April 6-10, 2002, San Francisco, California, USA

94th American Association for Cancer Research, April 5-9, 2003, Toronto, Ontario, Canada

95nd American Association for Cancer Research,, March 27-31, 2004, Orlando, Florida, USA

Inaugural AASP Conference, June 4-6, 2004, Beijing, China

l         Yang Bo and Reynolds CP: Tirapazamine cytotoxicity for neuroblastoma is p53-ependent. Proc Amer Assoc Cancer Res 2004;45:3837

l         Zmora O, Cascio MJ., Wan Z, Yang Bo, Keshelava N, Reynolds C.P. Multidrug resistance in neuroblastoma cell lines is not associated with altered mRNA expression for ceramide pathway enzymes. Proc Amer Assoc Cancer Res 2004;45:608.

l         Yang Bo, Keshelava N, Wan Z, Case MC, Groshen S, Hall A, Reynolds CP: Glutathione (GSH) and RNA expression of GSH synthesis and utilization enzymes are increased in drug-resistant neuroblastoma cell lines. Proc Amer Assoc Cancer Res 2003;44:1273

l         Guo WX, Yang Bo, Kong GY, and Maurer B: Suppression of N-(4-hydroxyphenyl) retinamide-induced cytotoxicity in ALL leukemia cell lines by piceatannol, protein-tyrosine kinase inhibitor. Proc Amer Assoc Cancer Res 2003; 44:606

l         Chen P, Maurer B, Yang B, and Reynolds CP: Fenretinide-induced cytotoxicity, ceramide induction, and stimulation of ceramide synthetic enzyme activity in a neuroblastoma cell line are inhibited by hypoxia. Proc Amer Assoc Cancer Res 2003;44:1272,

l         Yang Bo, Keshelava N, Anderson CP, Reynolds CP: Antagonism of buthionine sulfoximine cytotoxicity for human neuroblastoma cell lines by hypoxia is reversed by the bioreductive agent tirapazamine. Proc Amer Assoc Cancer Res 2002; 43:258

 

Editorial Position:

Corresponding Editors

 

Other Important Activities:

·         Member of American Association for Cancer Research

·         Secretary General of Zhejiang Pharmacology Society