Bu Beng YEAP

General and personal
Nationality: Australian Permanent Resident
Registration: Medical Board of Australia
Address: School of Medicine and Pharmacology, Level 2, T Block, Fremantle Hospital, Fremantle, Western Australia 6160.
Telephone: 08 9431 3229
Fax: 08 9431 2977
Email: byeap@cyllene.uwa.edu.au

Current employment
4 May 2009 to present: Professor, School of Medicine and Pharmacology, Faculty of Medicine and Dentistry, University of Western Australia
(Associate Professor from 13 Nov 2007 to 3 May 2009)
(Senior Lecturer from 7 Aug 2000 to 12 Nov 2007)
7 Aug 2000 to present: Consultant Physician and Endocrinologist, Fremantle Hospital, Western Australia 6160.

Qualifications
2001: Doctor of Philosophy (PhD), Pass with Distinction, Department of Medicine, Faculty of Medicine and Dentistry, UNIVERSITY OF WESTERN AUSTRALIA.
1996: Fellowship of the Royal Australasian College of Physicians (FRACP), ROYAL AUSTRALASIAN COLLEGE OF PHYSICIANS.
1988: Bachelor of Medicine, and Bachelor of Surgery (MB,BS), Distinction in Pathology, The Medical College of St Bartholomew's Hospital, UNIVERSITY OF LONDON, United Kingdom.

Title of PhD thesis
2001: Post-transcriptional regulation of androgen receptor gene expression in human prostate and breast cancer cells: identification and characterisation of novel RNA-protein interactions. Supervisor: Prof Peter J Leedman, UNIVERSITY OF WESTERN AUSTRALIA

Postgraduate prizes and awards
2013 Recipient - The US Endocrine Society’s International Award for Publishing Excellence in The Journal of Clinical Endocrinology & Metabolism (authorship of one of top 14 clinical research papers in JCEM in 2012)
2008 Finalist - Endocrine Society of Australia CSL Bryan Hudson Clinical Endocrinology Award
2007 Finalist - Endocrine Society of Australia Mayne Pharma Bryan Hudson Clinical Endocrinology Award
2002 Recipient - Raine Medical Research Foundation Certificate of Distinction and Travel Award
2002 Recipient - The Endocrine Society (USA) Travel Grant Award
1998 Recipient - The Prostate Cancer Foundation of Australia Travel Award
1997 Winner - Novartis Junior Investigator Award, Endocrine Society of Australia, presented at the 40th Annual Scientific Meeting of the Endocrine Society of Australia, Canberra, 1997.
1997 Winner - Young Clinical Investigator Award, Royal Perth Hospital, Perth, 1997.
1997 Winner - Beckman Student Prize, presented at the 8th Combined Biological Sciences Meeting, Perth, 1997.
1996 Winner - Promega Essay Prize, presented at the 7th Combined Biological Sciences Meeting, Perth, 1996.
1996 Recipient - Australian and New Zealand Society for Cell Biology Merit Award for an oral presentation at the 7th Annual Combined Biological Sciences Meeting, Perth, 1996.

Undergraduate prizes and scholarships
1988 Winner - Brackenbury and Waring Scholarship in Surgery
1988 Winner - Walsham Prize in Surgical Pathology
1988 Winner - Skynner Prize in Child Health

1988 Winner - Hilton Prize in Medicine
1988 Proxime Accesit - Brackenbury and Bourne Scholarship in Medicine

Health service appointments
30 Nov 2000 to 10 Feb 2013: Head, Department of Endocrinology and Diabetes, FREMANTLE HOSPITAL, FREMANTLE WA 6160.
6 Mar 2006 to 31 Dec 2006: Consultant Diabetologist, Ambulatory Care Chronic Disease Management, SOUTH METROPOLITAN AREA HEALTH SERVICE, WA.
8 Mar 2002 to 28 Nov 2003: Director of Physician Training, FREMANTLE HOSPITAL, FREMANTLE WA 6160.

University appointments
13 Mar 2001 to 31 Dec 2006: Clinical Sub-Dean, Faculty of Medicine and Dentistry, UNIVERSITY OF WESTERN AUSTR ALIA, FREMANTLE HOSPITAL, FREMANTLE WA 6160.

University responsibilities
2014: Academic liaison, School of Medicine and Pharmacology, University of Western Australia, for the Fiona Stanley Hospital, Western Australia
2011-2012: Head, Fremantle Hospital Unit, School of Medicine and Pharmacology, Faculty of Medicine and Dentistry
2010: Deputy Head, Fremantle Hospital Unit, School of Medicine and Pharmacology, Faculty of Medicine and Dentistry
2007: Chair, Undergraduate Committee and Director of Teaching, School of Medicine and Pharmacology, and Member, Medical Curriculum Committee, Faculty of Medicine and Dentistry
2006-2007: Coordinator, 5th Year Medicine Clinical Attachment, (IMED 5561/2) Faculty of Medicine and Dentistry
2004-2006: Member, Board of the Graduate Research School, University of Western Australia
2003-2005: Member, Biological Sciences Sub-committee, UWA Research Grants Scheme, University of Western Australia
2001-2005: Coordinator, 4th Year Medicine Clinical Attachment (Medicine 430), Faculty of Medicine and Dentistry
2003-2004: Chair, Year 3/4 Committee, Faculty of Medicine and Dentistry
2000-2004: Member, Evaluation Committee, Faculty of Medicine and Dentistry

Membership of professional associations
1. Member, Endocrine Society of Australia (1994 to present)
Member, Council, ESA (2006 to present)
Honorary Treasurer, ESA (2008/9)
Chair, Local Organising Committee, 48th Annual Scientific Meeting, Perth 2005
2. Fellow, Royal Australasian College of Physicians (awarded 1996)
Member, Adult Medicine Divisional Committee, RACP (2001-2005)
Member, Council, RACP (2002-2005)
3. Member, The Endocrine Society (USA) (1998 to present)
4. Member, Australian Diabetes Society (2001 to present)
5. Member, Australian Atherosclerosis Society (2006 to 2012)

Publications

1. Golledge J., Hankey G.J., Yeap B.B., Almeida O.P., Flicker L., Norman P.E. Reported high salt intake is associated with increased prevalence of abdominal aortic aneurysm and larger aortic diameter in older men. PLoS ONE: in press, accepted 20 June 2014.
   
2. Yeap B.B., Divitini M.L., Gunton J.E., Olynyk J.K., Beilby J.P., McQuillan B., Hung J., Knuiman M.W. Higher ferritin levels, but not serum iron or transferrin saturation, are associated with Type 2 diabetes mellitus in adult men and women free of genetic haemochromatosis. Clinical Endocrinology: in press, accepted 7 June 2014.
   
3. Brand J.S., Rovers M.M., Yeap B.B., Schneider H.J., Tuomainen T-P., Haring R., Corona G., Onat A., Maggio M., Bouchard C., Tong P.C.Y., Chen R.Y.T., Akishita M., Gietema J.A., Gannage-Yared M-H., Unden A-L., Hautanen A., Goncharov N.P., Kumanov P., Chubb S.A.P., Almeida O.P., Wittchen H-U., Klotsche J., Wallaschofski H., Volzke H., Kauhanen J., Salonen J.T., Ferrucci L., van der Schouw Y.T. Testosterone, sex hormone-binding globulin and the metabolic syndrome in men: An individual participant data meta-analysis of observational studies. PLoS ONE: in press, accepted 28 May 2014.
   
4. Wong Y.Y.E., Hyde Z., McCaul K.A., Yeap B.B., Golledge J., Hankey G.J., Flicker L., In older men, lower plasma 25-hydroxyvitamin D is associated with reduced incidence of prostate, but not colorectal or lung cancer. PLoS ONE: in press, accepted 22 May 2014.
   
5. Yeap B.B. Hormonal changes and their impact on cognition and mental health of ageing men. Maturitas: in press, accepted 20 May 2014.
   
6. Yeap B.B., Knuiman M.W., Divitini M.L., Handelsman D.J., Beilby J.P., Beilin J., McQuillan B., Hung J. Differential associations of testosterone, dihydrotestosterone and estradiol with physical, metabolic and health-related factors in community-dwelling men aged 17-97 years from the Busselton Health Survey. Clinical Endocrinology: in press, accepted 9 Jan 2014.
   
7. Golledge J., Clancy P., Hankey G.J., Yeap B.B., Norman P.E. Serum endostatin concentrations are higher in men with symptoms of intermittent claudication. Disease Markers: in press, accepted 19 Dec 2013.
   
8. Yeap B.B., Flicker L. Hormones and cardiovascular disease in older men. Journal of the American Medical Directors Association: in press, accepted 4 Dec 2013.
   
9. Sim M., Dawson B., Landers G., Swinkels D.W., Tjalsma H., Yeap B.B., Trinder D., Peeling P. Oral contraception does not alter typical post-exercise interleukin-6 and hepcidin levels in females. Journal of Science and Medicine in Sport: in press, accepted 13 November 2013.
   
10. Almeida O.P., Yeap B.B., Hankey G.J., Golledge J., Flicker L. Association of depression with sexual and daily activities: a community study of octogenarian men. American Journal of Geriatric Psychiatry: in press, accepted 17 September 2013.
    
11. Almeida O.P., Hankey G.J., Yeap B.B., Golledge J., Flicker L. The triangular association of ADH1B genetic polymorphism, alcohol consumption and the risk of depression in older men. Molecular Psychiatry: in press, accepted 25 July 2013.
    
12. Almeida O.P., Yeap B.B., Hankey J.G., Golledge J., Flicker L. HDL cholesterol and the risk of depression over 5 years. Molecular Psychiatry 2014; 19: 637-638.
    
13. Almeida O.P., Ford A.H., Flicker L., Hankey G.J., Yeap B.B., Clancy P., Golledge J. Angiogenesis inhibition and depression in older men. Journal of Psychiatry & Neuroscience: 2014; 39: 200-205.
    
14. Jamrozik E., Hyde Z., Alfonso H., Flicker L., Almeida O., Yeap B., Norman P., Hankey G., Jamrozik K. The validity of self-reported versus hospital-coded diagnosis of stroke - a cross sectional and longitudinal study. Cerebrovascular Diseases 2014; 37: 256-262.
    
15. Golledge J., Clancy P., Maguire J., Lincz L., Koblar S., McEvoy M., Attia J., Levi C., Sturm J., Almeida O.P., Yeap B.B., Flicker L., Norman P., Hankey G.J. Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not with stroke incidence. Stroke 2014; 45: 1064-1068.
    
16. Almeida O.P., Hankey G.J., Yeap B.B., Golledge J., Flicker L. Alcohol consumption and cognitive impairment in older men: a Mendelian randomisation study. Neurology: 2014; 82: 1038-1044.
    
17. Yeap B.B. Sex steroids and cardiovascular disease. Asian Journal of Andrology 2014; 16: 239-247.
    
18. Almeida O.P., Khan K.M., Hankey G.J., Yeap B.B., Golledge J., Flicker L. 150 minutes of moderate to vigorous physical activity per week predicts survival and successful ageing: a population-based 11-year longitudinal study of 12,201 older Australian men. British Journal of Sports Medicine: 2014; 48: 220-225.
    
19. Yeap B.B., Alfonso H., Chubb S.A.P., Handelsman D.J., Hankey G.J., Almeida O.P., Golledge J., Norman P.E., Flicker L. In older men an optimal plasma testosterone is associated with reduced all-cause mortality, and higher dihydrotestosterone with reduced ischaemic heart disease mortality, while estradiol levels do not predict mortality. Journal of Clinical Endocrinology and Metabolism: 2014; 99: E9-E18. Editorial commenting on this article: Anawalt B.D. Is men’s health just a single letter? Journal of Clinical Endocrinology and Metabolism: 2014; 99: 70-72.
    
20. Prina A.M., Huisman M., Yeap B.B., Hankey G.J., Flicker L., Brayne C., Almeida O.P. Hospital costs associated with depression in a cohort of older men living in Western Australia. General Hospital Psychiatry: 2014; 36: 33-37.
    
21. Almeida O.P., Hankey J.G., Yeap B.B., Golledge J., McCaul K., Flicker L. A risk table to assist health practitioners assess and prevent the onset of depression in later life. Preventive Medicine: 2013; 57: 878-882.
    
22. Yeap B.B., Alfonso H., Chubb S.A.P., Handelsman D.J., Hankey G.J., Golledge J., Flicker L., Norman P.E. Lower plasma testosterone or dihydrotestosterone, but not estradiol, are associated with symptoms of intermittent claudication in older men. Clinical Endocrinology: 2013; 79: 725-732.
    
23. Yeap B.B., Alfonso H., Hankey G.J., Flicker L., Golledge J., Norman P.E., Chubb S.A.P. Higher free thyroxine levels predict increased all-cause mortality in euthyroid older men. The Health In Men Study. European Journal of Endocrinology: 2013; 169: 401-408.
    
24. Wong Y.Y.E., McCaul K.A., Yeap B.B., Hankey G.J., Flicker L. Low vitamin D status is an independent predictor of increased frailty and all-cause mortality in older men: the Health In Men Study. Journal of Clinical Endocrinology and Metabolism: 2013; 98: 3821-3828
    
25. Golledge J., Clancy P., Yeap B.B., Hankey G.J., Norman P.E. Increased serum angiopoietin-2 is associated with abdominal aortic aneurysm prevalence and cardiovascular mortality in older men. International Journal of Cardiology: 2013; 167: 1159-1163 (IF=7.078)
    
26. Wong Y.Y.E., Golledge J., Flicker L., McCaul K.A., Hankey G.J., van Bockxmeer F.M., Yeap B.B., Norman P.E. Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men. Journal of Vascular Surgery: 2013; 58: 364-370
    
27. Wong Y.Y.E., Flicker L., Yeap B.B., McCaul K.A., Hankey G.J., Norman P.E. Is hypovitaminosis D associated with abdominal aortic aneurysm, and is there a dose-response relationship? European Journal of Vascular and Endovascular Surgery: 2013; 45: 657-664
    
28. Yeap B.B. Hormones and health outcomes in aging men. Experimental Gerontology: 2013; 48: 677-681.
    
29. Wong Y.Y.E., Almeida O.P., McCaul K.A., Yeap B.B., Hankey G.J., Flicker L. Homocysteine, frailty and all-cause mortality in older men: the Health In Men Study. Journal of Gerontology: Medical Sciences: 2013; 68: 590-598.
    
30. Yeap B.B., Chubb S.A.P., Lopez D., Ho K.K.Y., Hankey G.J., Flicker L. Associations of Insulin-like Growth Factor-I and its binding proteins, and testosterone, with frailty in older men. Clinical Endocrinology: 2013; 78: 752-759. (IF=3.168)
    
31. Prina A.M., Huisman M., Yeap B.B., Hankey G.J., Flicker L., Brayne C., Almeida O.P. Association between depression and general hospital outcomes among older men. Canadian Medical Association Journal: 2013; 185: 117-123. (IF=8.217)
    
32. Power B.D., Alfonso H., Flicker L., Hankey G.J., Yeap B.B., Almeida O.P. Change in body mass in later life and incident dementia. International Psychogeriatrics: 2013; 25: 467-478. (IF=2.240)
    
33. Almeida O.P., Alfonso H., Yeap B.B., Hankey G.J., Flicker L. Cardiovascular diseases do not influence the mental health outcome of older men with depression over 6 years. Journal of Affective Disorders: 2013; 144: 248-252.
    
34. Yeap B.B., Alfonso H., Chubb S.A.P., Puri G., Hankey G.J., Flicker L., Almeida O.P. Higher free thyroxine levels predict increased incidence of dementia in older men. The Health In Men Study. Journal of Clinical Endocrinology and Metabolism: 2012; 97: E2230-E2237. (IF=5.967) Editor’s choice for December 1, 2012, Vol. 97, Number 12, http://jcem.endojournals.org
    
35. Yeap B.B., Alfonso H., Chubb S.A.P., Handelsman D.J., Hankey G.J., Norman P.E., Flicker L. Reference ranges and determinants of testosterone, dihydrotestosterone and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a population-based cohort of older men. Journal of Clinical Endocrinology and Metabolism: 2012; 97: 4030-4039. (IF=5.967) Editor’s choice for November 1, 2012, Vol. 97, Number 11, http://jcem.endojournals.org
    
36. Yeap B.B., Araujo A.B., Wittert G.A. Do low testosterone levels contribute to ill-health during male ageing? Critical Reviews in Clinical Laboratory Sciences: 2012; 49: 168-182. (IF=5.250)
    
37. Wong Y.Y.E., Almeida O.P., McCaul K.A., Yeap B.B., Hankey G.J., van Bockxmeer FM, Flicker L. Elevated homocysteine is associated with poorer self-perceived physical health in older men: the Health In Men Study. Maturitas: 2012; 73: 158-163. (IF=2.767)
    
38. Yeap B.B. Testosterone therapy and mortality in US veterans. (Research highlight) Asian Journal of Andrology: 2012; 14: 667-668. (IF=1.521)
    
39. Almeida O.P., Yeap B.B., Alfonso H., Hankey G.J., Flicker L., Norman P.E. Older men who use computers have a lower risk of dementia. PLoS ONE: 2012; 7: e44239. (IF=4.092)
    
40. Alfonso H., Beer C., Yeap B.B., Hankey G.J., Flicker L., Almeida O.P. Perception of worsening health predicts mortality in older men: The Health in Men Study. Archives of Gerontology and Geriatrics: 2012; 55: 363-368. (IF=1.452)
    
41. Almeida O.P., Flicker L., Yeap B.B., Alfonso H., McCaul K., Hankey G.J. Aspirin decreases the risk of depression in older men with high plasma homocysteine. Translational Psychiatry: 2012; 2: e151.
    
42. Hyde Z., Flicker L., McCaul K.A., Almeida O.P., Hankey G.J., Chubb S.A.P., Yeap B.B. Associations between testosterone levels and incident prostate, lung, and colorectal cancer. A population-based study. Cancer Epidemiology, Biomarkers & Prevention: 2012; 21: 1319-1329. (IF=4.123)
    
43. Yeap B.B., Alfonso H., Chubb S.A.P., Walsh J.P., Hankey G.J., Almeida O.P., Flicker L. Higher free thyroxine levels are associated with frailty in older men. The Health In Men Study. Clinical Endocrinology: 2012; 76: 741-748. (IF=3.168)
    
44. Hyde Z., Flicker L., Hankey G.J., Almeida O.P., McCaul K.A., Chubb S.A.P., Yeap B.B. Prevalence and predictors of sexual problems in men aged 75-95 years: a population-based study. Journal of Sexual Medicine: 2012; 9: 442-453. (IF=3.552)
    
45. Yeap B.B., Chubb S.A.P., Flicker L., McCaul K.A., Ebeling P.R., Hankey G.J., Beilby J.P., Norman P.E. Associations of total osteocalcin with all-cause and cardiovascular mortality in older men. The Health In Men Study. Osteoporosis International: 2012; 23: 599-606. (IF 4.580)
    
46. Yeap B.B., Chubb S.A.P., McCaul K.A., Flicker L., Ho K.K.Y., Golledge J., Hankey G.J., Norman P.E. Associations of Insulin-like Growth Factor-I and its binding proteins with abdominal aortic aneurysm and aortic diameter in older men. European Journal of Endocrinology: 2012; 166: 191-197. (IF=3.423)
    
47. Hyde Z., Norman P.E., Flicker L., Hankey G.J., Almeida O.P., McCaul K.A., Chubb S.A.P., Yeap B.B. Low free testosterone predicts mortality from cardiovascular disease, but not other causes. The Health in Men Study. Journal of Clinical Endocrinology and Metabolism: 2012; 97: 179-189. (IF=5.967)
    
48. Almeida O.P., Alfonso H., Flicker L., Hankey G.J., Chubb S.A.P., Yeap B.B. Thyroid Hormones and Depression. The Health In Men Study. American Journal of Geriatric Psychiatry: 2011; 19: 763-770. (IF=3.638)
    
49. Wong B.X.W., Kyle R.A., Myhill P.C., Croft K.D., Quinn C.M., Jessup W., Yeap B.B. Dyslipidemic diabetic serum increases lipid accumulation and expression of stearoyl-CoA desaturase in human macrophages. Lipids: 2011; 46: 931-941. (IF=2.129)
    
50. Almeida O.P, Alfonso H., Yeap B.B., Hankey G.J., Flicker L. Complaints of difficulty to fall asleep increase the risk of depression in later life: the Health In Men Study. Journal of Affective Disorders: 2011; 134: 208-216. (IF=3.517)
    
51. Yeap B.B. Testosterone and sex in older men (Editorial). Medical Journal of Australia: 2011; 195: 61-62. (IF=2.813)
    
52. Lopez D., McCaul K.A., Hankey G.J., Norman P.E., Almeida O.P., Dobson A.J., Byles J.E., Yeap B.B., Flicker L. Falls, injuries from falls, health related quality of life and mortality in older adults with vision and hearing impairment – is there a gender difference? Maturitas: 2011; 69: 359-364. (IF=2.767)
    
53. Yeap B.B., Chubb S.A.P., McCaul K.A., Ho K.K.Y., Hankey G.J., Norman P.E., Flicker L. Associations of Insulin-like Growth Factor-I and its binding proteins 1 and 3 with all-cause and cardiovascular mortality in older men. The Health In Men Study. European Journal of Endocrinology: 2011; 164: 715-723. (IF 3.423)
    
54. Yeap B.B. Osteocalcin: an endocrine link between bone and glucose metabolism. Expert Review of Endocrinology and Metabolism: 2011; 6: 177-185.
    
55. Power B.D., Alfonso H., Flicker L., Hankey G.J., Yeap B.B., Almeida O.P. Body adiposity in later life and the incidence of dementia: the Health In Men Study. PLoS ONE: 2011; 6: e17902. (IF=4.092)
    
56. Hyde Z., Norman P.E., Flicker L., Hankey G.J., McCaul K.A., Almeida O.P., Chubb S.A.P., Yeap B.B. Elevated luteinizing hormone predicts ischaemic heart disease events in older men. The Health In Men Study. European Journal of Endocrinology: 2011; 164:569-577. (IF 3.423)
    
57. Wong B.X.W., Kyle R.A., Croft K.D., Quinn C.M., Jessup W., Yeap B.B. Modulation of macrophage fatty acid content and composition by exposure to dyslipidemic serum in vitro. Lipids: 2011; 46:371-380. (IF=2.129)
    
58. Beer C., Hyde Z., Almeida O.P., Norman P., Hankey G.J., Yeap B.B., Flicker L. Quality use of medicines and health outcomes among a cohort of community dwelling older men: an observational study. British Journal of Clinical Pharmacology: 2011; 71: 592-599. (IF=2.958)
    
59. Hyde Z., Flicker L., Hankey G.J., Almeida O.P., McCaul K.A., Chubb S.A.P., Yeap B.B. Prevalence of sexual activity and associated factors in men aged 75-95 years: A cohort study. Annals of Internal Medicine: 2010; 153: 693-702. (IF=16.733)
    
60. Yeap B.B., Beilin J., Shi Z., Knuiman M.W., Olynyk J.K., Chubb S.A.P., Bruce D.G., Milward E.A. The C282Y polymorphism of the hereditary hemochromatosis gene is associated with increased sex hormone-binding globulin and normal testosterone levels in men. Journal of Endocrinological Investigation: 2010; 33: 544-548. (IF=1.566)
    
61. Yeap B.B., Chubb S.A.P., Flicker L., McCaul K.A., Ebeling P.R., Beilby J.P., Norman P.E. Reduced serum total osteocalcin is associated with metabolic syndrome in older men through its association with hyperglycemia, waist circumference and serum triglycerides. European Journal of Endocrinology: 2010; 163: 265-272. (IF 3.423) Erratum published in European Journal of Endocrinology: 2011; 164: 315.
    
62. Hyde Z., Flicker L., Almeida O.P., Hankey G.J., McCaul K.A., Chubb S.A.P., Yeap B.B. Low free testosterone predicts frailty in older men. The Health in Men Study. Journal of Clinical Endocrinology and Metabolism: 2010; 95: 3165-3172. (IF 5.967)
    
63. Yeap B.B. Androgens and cardiovascular disease. Current Opinion in Endocrinology, Diabetes & Obesity: 2010; 17: 269-276. (IF=3.618)
    
64. Yeap B.B., Hyde Z., Norman P.E., Chubb S.A.P., Golledge J. Associations of total testosterone, sex hormone-binding globulin, calculated free testosterone, and luteinising hormone with prevalence of abdominal aortic aneurysm in older men. Journal of Clinical Endocrinology and Metabolism: 2010; 95: 1123-1130. (IF 5.967)
    
65. Hyde Z., Flicker L., Almeida O.P., McCaul K.A., Jamrozik K., Hankey G.J., Chubb S.A.P., Yeap B.B. Higher luteinizing hormone is associated with poor memory recall. The Health in Men Study. Journal of Alzheimer’s Disease: 2010; 19: 943-951. (IF=3.745)
    
66. Yeap B.B., Chubb S.A.P., Ho K.K.Y., Setoh J.W.S., McCaul K.A., Norman P.E., Jamrozik K., Flicker L. Insulin-like growth factor-I and its binding proteins 3 and 1 are differentially associated with metabolic syndrome in older men. European Journal of Endocrinology: 2010; 162: 249-257. (IF 3.423)
    
67. Yeap B.B., Chubb S.A.P., Hyde Z., Jamrozik K., Hankey G.J., Flicker L., Norman P.E. Lower serum testosterone is independently associated with insulin resistance in non-diabetic older men. The Health In Men Study. European Journal of Endocrinology: 2009; 161: 591-598. (IF 3.423)
    
68. Thong K.Y., Fegan P.G., Yeap B.B. Glycemic control in patients with Type 1 diabetes following provision of public hospital-funded insulin pumps. Medical Journal of Australia: 2009; 191: 291. (IF=2.813)
    
69. Yeap B.B., Beilin J., Shi Z., Knuiman M.W., Olynyk J.K., Bruce D.G., Milward E.A. Serum testosterone levels correlate with haemoglobin in middle-aged and older men. Internal Medicine Journal: 2009; 39: 532-538. (IF=1.541)
    
70. Yeap B.B. Testosterone and Growth Hormone in older men: for better or for worse? Key Paper Evaluation. Expert Review of Endocrinology and Metabolism: 2009; 4: 321-323.
    
71. Yeap B.B., Hyde Z., Almeida O.P., Norman P.E., Chubb S.A.P., Jamrozik K., Flicker L., Hankey G.J. Lower testosterone levels predict incident stroke and transient ischemic attack in older men. Journal of Clinical Endocrinology and Metabolism: 2009; 94: 2353-2359. (IF=5.967)
    
72. Myhill P.C., Yeap B.B. Severe hypercalcaemia in sarcoidosis with musculoskeletal involvement. Internal Medicine Journal: 2009; 39: 207-209. (IF=1.541)
    
73. Yeap B.B. Testosterone and ill-health in aging men. (Review) Nature Clinical Practice Endocrinology & Metabolism: 2009; 5: 113-121. (IF 7.545)
    
74. Yeap B.B. Controversies in Type 2 diabetes: an update. Australian Family Physician: 2009; 38: 22-25. (IF=0.729)
    
75. Yeap B.B. Are declining testosterone levels a major risk factor for ill-health in aging men? (Review) International Journal of Impotence Research: 2009; 21: 24-36. (IF=1.712)
    
76. Yeap B.B., Almeida O.P., Hyde Z., Norman P.E., Chubb S.A.P., Jamrozik K., Hankey G.J., Flicker L. Healthier lifestyle predicts higher circulating testosterone in older men. The Health In Men Study. Clinical Endocrinology: 2009; 70: 455-463. (IF=3.168)
    
77. Yeap B.B. The role of testosterone in older men: recent advances and future directions. (Editorial) Expert Review of Endocrinology and Metabolism: 2008; 3: 415-418.
    
78. Verdile G., Yeap B.B., Clarnette R.M., Dhaliwal S., Burkhardt M.S., Chubb S.A.P., De Ruyck K., Rodrigues M., Mehta P.D., Foster J.K., Bruce D.G. and Martins R.N. Luteinizing hormone levels are positively correlated with plasma amyloid-β-protein levels in elderly men. Journal of Alzheimer’s Disease: 2008; 14: 201-208. (IF=3.745)
    
79. Chubb S.A.P., Hyde Z., Almeida O.P., Flicker L., Norman P.E., Jamrozik K., Hankey G.J., Yeap B.B. Lower sex hormone binding globulin is more strongly associated with metabolic syndrome than lower total testosterone in older men. The Health In Men Study. European Journal of Endocrinology: 2008; 158: 785–792. (IF 3.423)
    
80. Davis T.M.E., Yeap B.B., Davis W.A., Bruce D.G. Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: The Fremantle Diabetes Study. Diabetologia: 2008; 51: 562–566. (IF=6.814)
    
81. Myhill P.C., Sillars B.A., Starkstein S., Annus T., Yeap B.B. Reduction in salivary cortisol concentration correlates with resolution of psychosis in Cushing’s syndrome. Journal of Neuropsychiatry and Clinical Neurosciences: 2008; 20: 113-115. (IF=2.505)
    
82. Almeida O.P., Yeap B.B., Hankey G.J., Jamrozik K., Flicker L. Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men. Archives of General Psychiatry: 2008; 65: 283-289. (IF=12.016)
    
83. Yeap B.B., Almeida O.P., Hyde Z., Chubb S.A.P., Hankey G.J., Jamrozik K., Flicker L. Higher serum free testosterone is associated with better cognitive function in older men, whilst total testosterone is not. The Health In Men Study. Clinical Endocrinology: 2008; 68: 404-412. (IF 3.168)
    
84. Hislop A.L., Fegan P.G., Schlaeppi M.J., Duck M., Yeap B.B. Prevalence and associations of psychological distress in young adults with Type 1 diabetes. Diabetic Medicine: 2008; 25: 91-96. (IF 2.902)
    
85. Yeap B.B. Type 2 diabetes mellitus: Guidelines for initiating insulin therapy. Australian Family Physician: 2007; 36: 549-553. (IF=0.729)
    
86. Yeap B.B., Almeida O.P., Hyde Z., Norman P.E., Chubb S.A.P., Jamrozik K., Flicker L. In men older than 70 years, total testosterone remains stable while free testosterone declines with age. The Health In Men Study. European Journal of Endocrinology: 2007; 156: 585-594. (IF 3.423)
    
87. Senanayake S., Brownrigg L.M., Panicker V., Croft K.D., Joyce D.A., Steer J.H., Puddey I.B., Yeap B.B. Monocyte-derived macrophages from men and women with Type 2 diabetes mellitus differ in fatty acid composition compared with non-diabetic controls. Diabetes Research and Clinical Practice: 2007; 75: 292-300. (IF=2.754)
    
88. Nyugen H.V., Mollison L.C., Taylor T.W., Chubb S.A.P., Yeap B.B. Chronic hepatitis C infection and sex hormone levels: effect of disease severity and recombinant interferon-alpha therapy. Internal Medicine Journal: 2006; 36: 362-366. (IF=1.541)
    
89. Hampel J.K.A., Brownrigg L.M., Vignarajah D., Croft K.D., Dharmarajan A.M., Bentel J.M., Puddey I.B., Yeap B.B. Differential modulation of cell cycle, apoptosis and PPAR2 gene expression by PPAR agonists ciglitazone and 9-hydroxyoctadecadienoic acid in monocytic cells. Prostaglandins, Leukotrienes and Essential Fatty Acids: 2006; 74: 283-293. (IF=3.367)
    
90. Burkhardt M.S., Foster J.K., Clarnette R.M., Chubb S.A.P., Bruce D.G., Drummond P.D., Martins R.N., Yeap B.B. Interaction between testosterone and Apolipoprotein E4 status on cognition in healthy older men. Journal of Clinical Endocrinology and Metabolism 2006; 91: 1168-1172. (IF=5.967)
    
91. Knight B., Yeap B.B., Yeoh G.C., Olynyk J.K. Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator-activated receptor (PPAR) family member gamma, but not alpha or delta. Carcinogenesis 2005; 26: 1782-1792. (IF=5.702)
    
92. Yeap B.B., Platell C.F., Ferrari P. Apparent Addison’s disease following ileostomy. Nephrology 2005; 10: 537-538. (IF=1.311)
    
93. Yeap B.B., Wilce J.A., Leedman P.J. The androgen receptor mRNA. Bioessays 2004; 26: 672-682. (IF=4.954)
    
94. Gillett M.J., Martins R.N., Clarnette R.M., Chubb S.A.P., Bruce D.G., Yeap B.B. Relationship between testosterone, sex hormone binding globulin and plasma amyloid beta peptide in older men with subjective memory loss or dementia. Journal of Alzheimer’s Disease 2003; 5: 267-269. (IF=3.745) Commentary on this manuscript: Petanceska S.S. Age-associated androgen deficiency and Alzheimer's disease: A case in the making? Journal of Alzheimer’s Disease 2003; 5: 271-273.
    
95. Yeap B.B., Voon D.C., Vivian J.P., McCulloch R., Thomson A.M., Giles K., Czyzyk-Krzeska M.F., Furneaux H., Wilce M.C., Wilce J., Leedman P.J. Novel binding of HuR and Poly (C) binding protein to a conserved UC-rich motif within the 3’ untranslated region of the androgen receptor messenger RNA. Journal of Biological Chemistry 2002; 277: 27183-27192. (IF=4.773)
    
96. Yeap B.B. Current management options for primary care diabetes. Australian Family Physician 2001; 30: 1122-1128. (IF=0.729)
    
97. Yeap B.B., Leedman P.J. Combined pituitary hormone deficiency – Lessons from the murine models. European Journal of Endocrinology 1999; 141: 211-213. (IF 3.423)
    
98. Yeap B.B., Krueger R.G., Leedman P.J. Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells. Endocrinology 1999; 140: 3282-3291. (IF 4.459)
    
99. Lavin J.H., Wittert G.A., Andrews J., Yeap B., Wishart J.M., Morris H.A., Morley J.E., Horowitz M., Read N.W. Interaction of insulin, glucagon-like peptide 1, gastric inhibitory polypeptide, and appetite in response to intraduodenal carbohydrate. American Journal of Clinical Nutrition 1998; 68: 591-598. (IF=6.669)
    
100. Yeap B.B., O’Leary P., Michelangeli V.P., Leedman P.J. Autoimmune thyroid disease: Recent advances in the era of cloned autoantigens. Clinical Biochemist Reviews 1997; 18: 133-141.
     
101. Yeap B.B., Russo A., Fraser R.J., Wittert G.A., Horowitz M. Hyperglycemia affects cardiovascular autonomic nerve function in normal subjects. Diabetes Care 1996; 19: 880-882. (IF=8.087)
     
102. Burnet R.B., Yeap B.B., Chatterton B.E., Gaffney R.D. Chronic fatigue syndrome: is total body potassium important? (Research letter) Medical Journal of Australia 1996; 164: 384. (IF=2.813)
     
103. Judd S.J., Wong J., Saloniklis S., Maiden M., Yeap B., Filmer S., Michailov L. The effect of alprazolam on serum cortisol and luteinizing hormone pulsatility in normal women and in women with stress-related anovulation. Journal of Clinical Endocrinology and Metabolism 1995; 80: 818-823. (IF 5.967)

Book chapters

1. Yeap B.B., Braunstein G.D.
   Investigation and management of gynecomastia.
   In: Endocrine Essentials
   Editor: Anawalt B.D.
   The Endocrine Society, Chevy Chase 2012; Chapter 21: 167-177.
2. Ferrari P., Yeap B.B.
   The hypertension patient with laboratory findings: Role of cortisol.
   In: Advanced Therapy in Hypertension and Vascular Disease
   Editors: Mohler E.R., Townsend R.R.
   Decker Inc, Hamilton 2006; Chapter 40: 339-346.

Other publications

1. Yeap B.B. Low testosterone and Type 2 diabetes in men. Medical Forum WA: in press
2. Yeap B.B. and Rajan G. Pituitary hormone deficiency following motor vehicle-related traumatic brain injury. The Pituitary Connection 2014; 67: 1-5.
3. Yeap B.B. Current concepts of low testosterone levels in ageing men. Endocrinology Today 2012; 1: 12-16.
4. Yeap B.B. Don’t be afraid of injecting insulin. Diabetes Management 2009; 29: 22.
5. Yeap B.B. Lower testosterone predicts ill-health in older men. Medical Forum WA 2009 July: 21.
6. Yeap B.B. Good diabetes control prevents heart attacks and saves lives. Medical Forum WA 2009 June: 22.

Editorial board membership
Member, Editorial Board, the Journal of Clinical Endocrinology and Metabolism
1st Jan 2014 to 31st Dec 2017

Invited guest speaker at international conferences

1. Yeap B.B.
   Hormones and health outcomes in ageing men
   Invited lecture
   11th International Symposium on the Neurobiology and Neuroendocrinology of Ageing
   Bregenz, Austria, 29 Jul to 3 Aug 2012
2. Yeap B.B.
   Hormones and health outcomes in older men: Perspectives from the Health In Men Study.
   Plenary lecture
   6th Biennial Meeting of the Asia-Pacific Society for the Study of Aging Male
   Busan, South Korea, 0945-1030, 3 Sep 2011
3. Yeap B.B., Braunstein G.D.
   Investigation and management of gynecomastia
   Case management forum
   ENDO 2011, Boston, USA, 0830-0915 and 1300-1345, 6 June 2011
4. Yeap B.B.
   Testosterone: Cause of CVA or Stroke of Fortune
   NIDDK Anniversary Symposium: Testosterone & the Male Brain
   ENDO 2010, San Diego, USA, 0930-1100, 19 June 2010

Invited guest speaker at national conferences

1. Yeap B.B.
   The changing evidence base in men’s health: Update on testosterone.
   Andrology Australia Forum, Launceston, 0900-0930, 15 June 2014.
2. Yeap B.B.
   Debate: Androgen insufficiency in patients with diabetes.
   Directions in Diabetes, Sydney, 1330-1415, 12 Oct 2013.
3. Yeap B.B.
   High Insulin Requirements: Insulin Resistance and Other Causes.
   Diabetes Expert Forum, Sydney, 1145-1230, 7 Mar 2010.
4. Yeap B.B.
   Incretin Mimetics & DPP IV Inhibitors
   Diabetes Face to Face, Sydney, 1400-1430, 1 Jun 2008.
5. Yeap B.B.
   PPARs in macrophages: the ABCs, LXR and SCD.
   Australian Atherosclerosis Society Annual Scientific Meeting, Darwin, 0830-0900, 22 Oct 2005.

Other international and national speaker invitations

1. Yeap B.B.
   Hormones and health of ageing men: results from the WA Health in Men Study.
   Austin Health Endocrine Meeting, Melbourne, 1215-1315, 19 April 2013.
2. Yeap B.B.
   Reproductive hormones in ageing men.
   Endocrine and Reproductive Biology Society of Western Australia, Perth, 1630-1710, 23 April 2012.
3. Yeap B.B.
   Hormones and health outcomes in older men: findings from the Western Australian Health in Men Study.
   Austin Health Endocrine Meeting, Melbourne, 1230-1330, 24 Feb 2012.
4. Yeap B.B.
   Hormones and health outcomes in older men: results from the Health In Men Study
   Seminar, Boston University School of Medicine, Boston, USA, 0830-0915, 8 June 2011.
5. Yeap B.B.
   Hormones and ill-health in ageing men: Results from the Health In Men Study.
   Endocrine Grand Round, University of California San Diego, San Diego, USA, 0900-1000 23 June 2010.
6. Yeap B.B.
   Hormone levels as predictors of ill-health in ageing men: Insights from the Health In Men Study.
   South Australian Endocrinology Meeting, Victor Harbour, 15 Nov 2008.
7. Yeap B.B.
   Career development workshop: Academic medicine and clinical endocrinology for junior clinicians.
   Endocrine Society of Australia Annual Scientific Meeting, Melbourne, 0800-0830, 26 Aug 2008.

Chair/Co-chair of sessions at national conferences

1. Co-chairs: Bu Yeap and Emily Gianatti
   ESA Orals - Bryan Hudson Clinical Award and Case Studies
   1330-1530 26 Aug 2014
   Endocrine Society of Australia Annual Scientific Meeting, Melbourne, 2014.
2. Co-chairs: Bu Yeap and Caroline Jung
   ESA Orals - Bryan Hudson Clinical Award and Case Studies
   1330-1530 27 Aug 2013
   Endocrine Society of Australia Annual Scientific Meeting, Sydney, 2013.
3. Chair: Bu Yeap
   ESA Special Session – presentation by David Looke “Antibiotic resistance, guidelines and stewardship”
   1400-1430 27 Aug 2012
   Endocrine Society of Australia Annual Scientific Meeting, Gold Coast, 2012.
4. Chair: Bu Yeap
   ADS Posters – Glucose (2)
   1600-1730 31 Aug 2011
   Annual Scientific Meeting of the Australian Diabetes Society, Perth, 2011.
5. Chair: Bu Yeap
   ESA Mid-Career Award Lecture by Mathis Grossmann “Low testosterone in men: studies in diabetes and prostate cancer”
   1630-1700 30 Aug 2011
   Endocrine Society of Australia Annual Scientific Meeting, Perth, 2011.
6. Co-chairs: Bu Yeap and Jerry Greenfield
   ADS Orals – CVD Renal Outcomes (Clinical)
   1130-1300 2 Sep 2010
   Annual Scientific Meeting of the Australian Diabetes Society, Sydney, 2010.
7. Co-chairs: Jerry Greenfield and Bu Yeap
   ADS Orals – Interventions in Diabetes (Clinical)
   0830-1000 2 Sep 2010
   Annual Scientific Meeting of the Australian Diabetes Society, Sydney, 2010.
8. Co-chairs: Bu Yeap and Jui Ho
   ESA Orals – Bryan Hudson Clinical Award and Case Studies
   1400-1600 31 Aug 2010
   53rd Annual Scientific Meeting of the Endocrine Society of Australia, Sydney 2010.
9. Chair: Bu Yeap
   Endocrine Society of Australia Plenary Lecture by Joseph Verbalis “Hyponatremia: 2009 and Beyond”
   0830-0930 25 Aug 2009
   52nd Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide 2009.
10. Co-chairs: Andrew Brown and Bu Yeap
    Gene Expression and Regulation in Atherosclerosis.
    0900-0945 22 Oct 2005
    Australian Atherosclerosis Society Annual Scientific Meeting, Darwin 2005.
11. Co-chairs: Bu Yeap and Helen MacLean
    Session 28 – ESA Orals: Androgens and Androgen Action.
    1000-1200 6 Sep 2005
    48th Annual Scientific Meeting of the Endocrine Society of Australia, Perth 2005.
12. Co-chairs: Julie Owens and Bu Yeap
    Session 32 – ESA Orals #9: Adipocytokines and Metabolism.
    1500-1700 24 Aug 2004
    47th Annual Scientific Meeting of the Endocrine Society of Australia, Sydney 2004.

ROLE AS EXPERT REVIEWER
Manuscript reviewer for the following journals: Journal of Clinical Endocrinology and Metabolism, European Journal of Endocrinology, Clinical Endocrinology, Molecular and Cellular Endocrinology, Diabetes Care, Metabolism, Diabetes Research and Clinical Practice, American Journal of Epidemiology, Drugs, Journal of Bone and Mineral Research, Osteoporosis International, Journal of Sexual Medicine, Journal of Diabetes and its Complications, Cardiovascular Diabetology, BMC Medicine, Journal of Alzheimer’s Disease, Experimental Gerontology, Hormone and Metabolic Research, Asian Journal of Andrology, Vascular Health and Risk Management, Journal of the American Medical Association, Medical Journal of Australia, Internal Medicine Journal, Australian Family Physician, Australian Medicines Handbook, Clinical Drug Investigation and Expert Opinion in Pharmacotherapy.
Grant reviewer for the following major funding bodies: NHMRC, National Heart Foundation and the Diabetes Australia Research Trust.
Member of NHMRC Grant Review Panel: 2010, 2011 and 2012.
Member of NHMRC Assigners Academy: 2013, 2014.

Previous employment
12 Apr 1999 to 6 Aug 2000: Consultant General Physician and Endocrinologist (four sessions), Department of Internal Medicine, ROYAL PERTH HOSPITAL, PERTH, WA 6001.
12 Feb 1996 to 6 Aug 2000: NH & MRC Postgraduate Medical Research Scholar and PhD student, University Department of Medicine, ROYAL PERTH HOSPITAL, PERTH, WA 6001. Supervisor: A/Prof. P. J. Leedman.
13 Feb 1995 to 6 Feb 1996: Endocrinology Registrar and Advanced Trainee, Department of Endocrinology, ROYAL ADELAIDE HOSPITAL, ADELAIDE, SA 5000. Head of Department: Dr. P. Harding
2 Feb 1994 to 29 Jan 1995: Endocrinology Registrar and Advanced Trainee, Department of Endocrinology, FLINDERS MEDICAL CENTRE, BEDFORD PARK, SA 5042. Head of Department: A/Prof. S. Judd
19 Mar 1990 to 16 Jan 1994: Resident Medical Officer and Registrar, SIR CHARLES GAIRDNER HOSPITAL, NEDLANDS, WESTERN AUSTRALIA 6009.
1 Aug 1989 to 31 Jan 1990: Senior House Officer, General and Renal Medicine to Dr A. Brownjohn and Dr J. Turney, Consultant General Physicians and Nephrologists, LEEDS GENERAL INFIRMARY, Leeds, United Kingdom.
1 Feb 1989 to 31 Jul 1989: Pre-Registration House Surgeon to Mr J. Wellwood, Consultant Surgeon, WHIPPS CROSS HOSPITAL, London, United Kingdom.
1 Aug 1988 to 31 Jan 1989: Pre-Registration House Physician to Professor G. M. Besser and Professor J. A .H. Wass, Department of Endocrinology, and to Dr E. A. M. Gale, Department of Diabetes, ST BARTHOLOMEW'S HOSPITAL, London, United Kingdom.