DATE
PREPARED:
10/22//04
SUSAN H. BENOFF, Ph.D.
PROFESSIONAL ADDRESS: North
Shore-Long Island Jewish Research Institute
350
Community Drive, Room 125
Manhasset,
New York 11030
Tel:
516-562-1121/1050/1049
Fax:
516-562-1022
E-mail:
sbenoff@nshs.edu
EDUCATION:
1971 B.A. Biology
Queens
College, City University of New York, Queens, N.Y.
1977 Ph.D. Cell
Biology Albert Einstein College of
Medicine, Yeshiva University, Bronx, N.Y.
POSTDOCTORAL
TRAINING:
1979 Cell
Biology Belfer
Institute for Advanced Biomedical Studies, Albert Einstein College of Medicine,
Yeshiva
University, Bronx, N.Y.
1983 Molecular
Biology DNA
Sequencing Course, The Waksman Institute of Molecular Biology, The State
University
of
New Jersey, Rutgers, N.J.
1992 Developmental
Biology The American Fertility Society,
Twenty‑Fifth Annual Biology Postgraduate Program, Course
VIII ‑ C Oocytes and Embryos: Basic and
Clinical Considerations.
1995 Developmental
Biology The Society for Gynecologic
Investigation, Postgraduate BiologyCourse: Biology of Gametes.
1995 Toxicology The
American Society for Andrology, Postgraduate Courses: Prenatal Determinants of
Postnatal
Development; Environmental Effects on Human Semen Quality and on Reproductive
Development.
1996 Endocrinology The
American Society of Andrology Post‑Graduate Course: Endocrinology of the Male,
From
Head
to Testes.
1996 Reproductive
Immunology The
Society for Gynecologic Investigation, Postgraduate Course II, Immunology
Update,
Topics in Basic and Applied Reproductive Immunobiology
1996 Cell
Biology American
Association of Biolanalysts Eastern Region Workshop, Andrology and Embryology
-
"Back to Basics"
1997 Reproductive
Biology The
American Society of Andrology Postgraduate Course: Animal and Human
Reproduction:
Genetic
and Technological Advances
1997 Toxicology The
American Society for Reproductive Medicine, Thirtieth Annual Postgraduate
Program,
Course
XI Effects of Toxicant Exposure on Sperm and Oocyte Quality
2003 Bioinformatics Silicon
Genetics GeneSpring Workshops Levels I, II, III and IV
PROFESSIONAL
EXPERIENCE:
1980-1987 Assistant
Professor Department
of Anatomy and Cell Biology, SUNY-Health Science Center at Brooklyn,
Brooklyn,
N.Y.
1980-1981 Consultant Experimental
Polymer Culture Surfaces Development, Falcon Plastics, Becton
Dickinson
Research Center, Research Triangle Park, N.C.
1988 Senior
Scientist Laboratory
of Cell Biology and Product Development, Enzo Biochem Inc., NY, NY
1989 Consultant Special
Products Group, Enzo Biochem Inc., New York, N.Y.
1990 Visiting
Senior Scientist Live
Viral Vaccine Discovery and Development Research Virologist Program
Lederle-Praxis Biologicals, Pearl River, N.Y.
1991-2000 Director,
Molecular Biology Laboratories, Division of Human Reproduction, Department of
Obstetrics and
Gynecology, North Shore University Hospital, Manhasset, N.Y.
1995-Present Associate
Professor Department
of Obstetrics and Gynecology, New York University School of Medicine,
New
York, N.Y.
1995-Present Associate
Professor Department
of Cell Biology, Sackler Institute, New York University Post-Graduate
Medical
School, New York, N.Y.
2000-Present Director,
Fertility Research Laboratories Center
for Molecular and Cell Biology, North Shore-Long Island
Jewish
Resarch Institute, Manhasset, N.Y.
2000-2004 Associate
Investigator, Scientific Track, Center for Oncology & Cell Biology, North
Shore-Long Island
Jewish Research
Institute, Manhasset, NY
2004-Present Senior
Investigator, Scientific Track, Center for Oncology & Cell Biology, North
Shore-Long Island
Jewish Research
Institute, Manhasset, NY
AWARDS:
1980 Outstanding
Young Woman of America
1993 The
Society for Assisted Reproductive Technology Prize Paper (49th Annual Meeting
of the American Fertility
Society)
1994 The
General Program Prize Paper (50th Annual Meeting of the American Fertility
Society)
1995 The
General Program Prize Paper (51st Annual Meeting of the American Society for
Reproductive Medicine)
1996 The
Society for Male Reproduction and Urology Prize Paper (52nd Annual Meeting of the
American Society
for Reproductive Medicine)
1997 The
International Assisted Reproductive Technology/Andrology on Male Infertility
(International ARTA
Meeting, Alexandria, Egypt, September 1997)
1997 The
International Assisted Reproductive Technology/Andrology Award in Basic
Sciences
(International
ARTA Meeting, Alexandria, Egypt, September 1997)
1997 The
Poster Prize Award in Male Infertility (53rd Annual Meeting of the American
Society for Reproductive
Medicine)
1998 Poster
Prize Award (54th Annual Meeting of the American Society for Reproductive
Medicine)
1999 Best
Poster, International Symposium on Molecular Aspects of Male Reproductive
Toxicology
(Justus-Liebig-Universitat,
Giessen, Germany, November 1999)
2000 Research
Excellence Award for a Female Trainee/Fellow (25th Annual Meeting of the
American
Society of
Andrology)
2000 The
Society for Male Reproduction and Urology Prize Paper (56th Annual Meeting of
the American Society
for
Reproductive Medicine)
2000 2
Poster Prize Awards (56th Annual Meeting of the American Society for
Reproductive Medicine)
2001 Poster
Prize Award (57th Annual Meeting of the American Society for
Reproductive Medicine)
HONORS:
1980 Invited
Speaker, European Molecular Biology Organization Workshop on Muscle Culture in
the Study of
Genes
Expressed During Differentiation, Shoresh, Israel
1981 Co-Chairman,
Session C: Genetic Regulation, Fifty-Second Meeting of the Genetics Society of
America in
Conjunction
with the Twenty-Seventh Annual Meeting of the Genetics Society of Canada, North
Carolina State University, Raleigh, N.C.
1981,1983 Nominated
by the Faculty and Administration of the S.U.N.Y.-Health Science Center at
Brooklyn for the
Hirschl
and Presidential Young Investigator Award
1983 Fund
Raising Chairman, Women's Tennis Association Awards Dinner, March of Dimes
Birth Defects
Foundation
1986 Invited
Speaker, Use of Recombinant DNA Techniques in the Definition of Mutations
Causing Neuromuscular
Diseases,
The Royal Society of Medicine Foundation, New York, N.Y.
1992 Representative
for the Department of Obstetrics and Gynecology, Biotechnology Luncheon
Sponsored by the
New York
State Department of Economic Development's International Division, North Shore
University Hospital, Manhasset, N.Y.
1992 Representative
for the Department of Obstetrics and Gynecology, North Shore University
Hospital & Cold Spring Harbor Laboratory Joint Scientific Retreat, The Cold
Spring Harbor Laboratory
1992,1994,1996,1998, 2000,2002 Poster Presenter, Gordon Research Conference on Mammalian
Gametogenesis and Embryogenesis
1993 Nominated
for the Male Reproduction/Urology Prize Paper Award (49th Annual Meeting of the
American Fertility Society)
1993 Solicited
paper, Human Reproduction
1993,1995 Representative
for the Department of Obstetrics and Gynecology, North Shore University
Hospital, Cold Spring Harbor Laboratory & Picower Institute for Medical
Research Joint Scientific Retreat
1993,1995,
1997 Solicited paper, American Journal of
Reproductive Immunology
1993,1995,1997,1999,2001 Poster
Presenter, Gordon Research Conference on Fertilization and Activation of
Development
1993,1995 Solicited
editorial, Human Reproduction
1994,1995 Research
reviewed by Journal of NIH Research
1994 Chairman,
NICHD Contraceptive Development Branch Sponsored Workshop, Targets for
Contraceptive Development: The Sperm Membrane in Fertilization, Bethesda,
Maryland
1995 Solicited
review, Assisted Reproduction Reviews
1995,1996 Research
abstracted in YEAR BOOK OF INFERTILITY AND REPRODUCTIVE ENDOCRINOLOGY
1995 Research
findings highlighted at NIH Symposium: The NIH Program In Reproduction-A View
to the 21st Century, 28th Annual Meeting of The Society for the Study of
Reproduction
1995 Nominated
for The Society for Assisted Reproductive Technology Prize Paper Award (51st
Annual Meeting of the American Society for Reproductive Medicine)
1995 Nominated
for The Male Reproduction/Urology Prize Paper Award (51st Annual Meeting of the
American Society for Reproductive Medicine)
HONORS
(Cont’d.):
1995 Leader,
Roundtable Discussion, "Effect of Varicocele on Sperm Function", 51st
Annual Meeting of The American Society for Reproductive Medicine
1996 Instructor,
American Association of Bioanalysts Sponsored Workshop: ANDROLOGY AND
EMBRYOLOGY - BACK TO BASICS
1996,1998,1999,2000 Judge,
Lea Ronal/Shipley Ronal Invitational Science Fair
1997,1998 Solicited
review, Molecular Human Reproduction
1997 Solicited
review, Assisted Reproductive Technology and Andrology
1997 Solicited
manuscript, Archives of Sexually Transmitted Diseases and HIV
1997 Solicited
manuscript, Advances in Contraceptive Delivery Systems
1997 Member,
Ad Hoc Advisory Committee, Contraceptive Development Branch of the Center for
Population Research, NICHD/NIH
1997 Invited
Speaker, Seminar and Workshop: New Methods of Assessing Sperm Function, 53rd
Meeting of the American Society for Reproductive Medicine
1997-1999 Vice-President,
Women in Andrology
1998 Solicited
review, Human Reproduction Update
1998 Solicited
review, In: Baldi E. ed. Frontiers in Bioscience, Sperm biology: from Basic to
Clinic
1998 Nominated
for The Male Reproduction/Urology Prize Paper Award (54th Annual Meeting of the
American Society for Reproductive Medicine)
1998 Workshop
Chair, "Outcomes Assessment/Biomarkers of Exposure", International
Conference on Hazardous Substances and Male Reproductive Health, co‑sponsored
by NIEHS/Superfund Basic Research Program, Mt. Sinai School of Medicine
Research Program, NIOSH, N.Y. Academy of Medicine, EPA and ATSDR
1998 Invited
Speaker, Genetic Basis of Male Infertility ‑ What Do We Do With The
Information?, British Fertility Society Workshop, Annual Meeting of the British
Andology Society
1999-Present Member
of grant review committe, Wellcome Trust
1999-2000 President,
Women in Andrology
1999 Solicited
review, Human Fertility
1999 Invited
Speaker, Society for Male Reproduction and Urology Post‑Graduate Course,
"Laboratory Methods: Current Methods and A Look Towards the Future",
55th Annual Meeting of The American Society for Reproductive Medicine
1999 Invited
Speaker, International Symposium on Molecular Aspects of Male Reproductive
Toxicology, Justus-Liebig-Universitat, Giessen, Germany
2000 Invited
Speaker, Center for Population Research, NICHD/NIH
2000 Chair,
Nominating Committee, The Society for Male Reproduction and Urology
2000,2001 Solicted
review, Human Reproduction Update
2000 Solicited
paper, Andrologia
2000 Leader,
Roundtable Discussion, 56th Annual Meeting of The American Society for
Reproductive Medicine
2000-2001 Secretary/Treasurer,
The Society for Male Reproduction and Urology
2001 Invited
Speaker, Seminar and Workshop, "ABCs of Molecular Biology and Male
Infertility”, 57th Annual Meeting of The American Society for Reproductive
Medicine
2001-2002 Vice-President,
The Society for Male Reproduction and Urology
2001 Member,
NICHD Special Study Section for RFA HD-00-018, Microbocide Preclinical
Development Program (Declined)
2002 Member,
NICHD Special Study Section for RFA HD-01-011, Cooperative Contraceptive
Research Centers
2002 Invited
Speaker, Zinc Signals 2002
2002 Invited
Speaker, 6th Dies Andrologicus in Marburg, The Calcium Ion in Human
Reproduction
2002 Nominated for The Society for Male Reproduction
and Urology Prize Paper Award and for the General Program
Prize Paper Award (58th Annual Meeting of the
American Society for Reproductive Medicine)
2002 Invited
review, Chinese National Journal of Andrology (Declined)
2002-2003 President,
The Society for Male Reproduction and Urology
2002-2003
Member, American Society for Reproductive Medicine
Board of Directors
2002-2003
American Society for Reproductive Medicine Media and
Congressional Spokesman, Male Reproduction and
Urology
2003 Invited
Speaker, Zinc Signals 2003
2003
Member, NIDDK Special Emphasis Panel for ZDK1 GRB-9
M1 R, Urology Research Centers
2003 Member,
NICHD Special Study Section for “Male Site, Contraceptive Clinical Trials”
(Declined)
2003 Chair,
American Society for Reproductive Medicine’s Research Task Force
2003 Ad
hoc reviewer, NICHD Reproduction, Andrology and Gynecology Committee
Past
Support:
1971-1974 NIH
Genetics Traineeship
1974-1977 NIH
Predoctoral Traineeship
1977-1979 NIH
Cancer Program Postdoctoral Research Associate
1979-1980 (Declined) NIH
Postdoctoral Fellowship
1979 Muscular
Dystrophy Association Postdoctoral Fellowhip
1980-1982 NIH‑Biomedical
Research Support Grant
1980-1981 Becton
Dickinson Experimental Polymer Surfaces Development Award
1981,1982,1983 Muscular
Dystrophy Association Basic Research Grant
1981-1983,1984 New
York Heart Association Grant-in-Aid
1981,1982,1983 March
of Dimes Birth Defects Foundation/Basil O'Connor Starter Research Grant
1983-1984 March
of Dimes Continuing Research Grant
1983-1984,1985-1986 New
York Heart Association Participating Laboratory Fellowhip
1993-1995 HUMAN
SPERM ZONA ACCEPTOR: CHANGES WITH VARICOCELE LIGATION
American
Foundation for Urologic Disease/Searle Office Based Research Grant ($100,000)
1995-1996 MALE
CONTRACEPTION: DEFINING THE PRIMARY STRUCTURE OF THE CALCIUM ION CHANNEL IN THE
HUMAN SPERM
American
Society for Reproductive Medicine/Organon Inc. Research Grant in Reproductive
Medicine ($20,000)
1994-1998 HUMAN
SPERM ZONA ACCEPTOR: ENVIRONMENTAL EFFECTS
NIEHS
1 RO1 ES06100 ($961,722) (years 1-3)
1998-1999 EFFECT
OF BLOOD PLASMA LEAD ON REPRODUCTIVE HORMONES AND HUMAN MALE INFERTILITY
Research
and Development Funding, Serono Laboratories, Inc. ($8,350)
1998-2000 SPERM
PROGESTERONE RECEPTOR, K+ CHANNEL & Pb EXPOSURE
NIOSH
1 RO3 OH03584 ($79,900)
1999-2000 MOLECULAR
CLONING OF THE Pb2+‑SENSITIVE ION CHANNEL ASSOCIATED WITH THE SPERM SURFACE PROGESTERONE
RECEPTOR
American
Society for Reproductive Medicine/Organon Inc. Research Grant in Reproductive
Medicine ($20,000)
2000-2003 RENAL
FUNCTION IN CONGESTIVE HEART FAILURE
NHLBI
1 RO1 HL 61506 ($1,107,000) (Declined)
1998-2002 HUMAN
SPERM ZONA ACCEPTOR: ENVIRONMENTAL EFFECTS
NIEHS
2 RO1 ES06100 ($961,491) (years 4-6)
2000-2002 MALE
SUBFERTILITY BY Ni2+ POISONING OF Ca2+ CHANNELS?
CDC/NIOSH
1 R21 OH 07330 ($246,000)
Current
Support:
2000-2005 INCREASED
TESTICULAR Cd2+ & INFERTILITY WITH VARICOCELE
NIEHS
1 RO1 ES 10496 ($1,829,000) (years 1-5)
2002-2006 HUMAN
SPERM ZONA ACCEPTOR: ENVIRONMENTAL EFFECTS
NIEHS
2 RO1 ES06100 ($1,468,800) (years 7-11)
2003-2004
ACQUISITION OF A MASS SPECTROMETRY RESOURCE
NCRR
Shared Equipment Grant S10 RR018099
Pending
Support:
2004-2007
CIGARETTE SMOKE Cd EXPOSURE IN UTERO & LOW SPERM
COUNT
NIEHS 1
R21 ES012288-01 ($482,400)
CONFERENCE SUPPORT:
2002 Annual SMRU Traveling Scholar Conference
NICHD
R13 HD044249-01 ($10,000)
2003 Annual SMRU Traveling Scholar Conference
NICHD
R13 HD044249-02 ($10,000)
PATENTS
AND PATENT APPLICATIONS:
1994 Method
for Assessing Infertility By Binding of Mannose to Sperm Cells
, U.S. Patent No.
5,994,086
Date of Patent:
30 November 1999
1994 Male
Contraceptives, U.S. Serial No. 08/701/826
U.S.
Patent Number: 5,854,254
Date of
Patent: 29 December 1998
2000 Oligonucleotide
probes, assays and kits for varicocele associated infertility
U.S. Provisional
Patent Application No. 60/281,830 (Filed 5 October 2000)
2001 Oligonucleotides
for detecting male infertility
U.S.
Non-Provisional Patent Application (Filed 5 October 2001)
MAJOR
COMMITTEE ASSIGNMENTS:
Medical
School (S.U.N.Y.‑Health
Science Center at Brooklyn):
1981-1983 Finance
Committee, Department of Anatomy and Cell Biology
1981-1982 Seminar
Chairman, Department of Anatomy and Cell Biology
1982-1984 Committee
of the Faculty and Professional Staff, College of Medicine
1982-1983 Student
Recruitment Sub-committee, School of Graduate Studies
1985 Committee
on Nominations, Elections and Ballots, College of Medicine
Hospital:
1981-1984 Biohazard
and Recombinant DNA Advisory Committee, Institute for Basic Research in Mental
Retardation, Staten Island, N.Y.
1994-2000 Voting
member, Research, Clinical Investigation and Publications Committee, North
Shore University Hospital
MEMBERSHIPS,
OFFICES, AND COMMITTE ASSIGNMENTS IN PROFESSIONAL SOCIETIES:
1992-2000 American
Association for the Advancement of Science
1993-Present The
American Society for Reproductive Medicine
Abstract
Committee, 51st Annual Meeting, 1995
Abstract
Committee, 54th Annual Meeting, 1998
Abstract
Committee, 55th Annual Meeting, 1999
Oral
Session Moderator, 55th Annual Meeting, 1999
Oral
Session Moderator, 57th Annual Meeting, 2001
General
Program Committee, 58th Annual Meeting, 2002
Member,
ASRM Board of Directors, 2002-2003 (SMRU Representative)
General
Program Committee, 59th Annual Meeting, 2003
Oral
Session Moderator, 59th Annual Meeting, 2003
Chair,
ASRM Research Task Force, 2003-Present
Oral
Session Moderator, 60th Annual Meeting, 2004
1993-Present The
American Society of Andrology
Chairman,
Membership Committee, 1995-1998