ROBERT HOWARD GETZENBERG
Business Address: University
of Pittsburgh
Shadyside
Medical Center
Urology Research G-40
5200 Centre Avenue
E-mail: getzenbergrh@upmc.edu
Pittsburgh,
PA 15232
Business Phone:
(412)
623-3903
Business Fax: (412) 623-3904
Current Address:
Professor
and Director of Research of the Brady Urological Insitute
Johns Hopkins School of Medicine
Marburg 113
600 North Wolfe Street
Baltimore, MD 21287
410-502-3137
fax 410-955-0833
e-mail: rgetzen1@jhmi.edu
UNDERGRADUATE:
Degree Received
1983 –
1987 Rutgers
College, Rutgers University B.A.
w/ High Honors Microbiology
New
Brunswick, New Jersey 1987
GRADUATE:
Degree Received Major
Professor
Dates Attended Name
and Location of Institution and Year and Discipline
1987-1992 Johns
Hopkins University School of Ph.D.
– 1992 Donald
S. Coffey, Ph.D.
Medicine,
Baltimore, Maryland Biochemistry,
Cellular
&
Molecular Biology
POST-GRADUATE:
1992-1994 Yale
University School of Medicine Eric
R. Fearon, M.D., Ph.D.
New
Haven, Connecticut Postdoctoral
Fellowship
Department
of Pathology
ACADEMIC:
2003 – Present Department
of Urology Professor
w/tenure and
University
of Pittsburgh School of Medicine Director
of Urological
Pittsburgh,
Pennsylvania Research
2003 – Present Department
of Pathology Professor
w/tenure
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
2003 – Present Department
of Pharmacology Professor
w/tenure
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
2000 – 2003 Department
of Urology Associate
Professor w/tenure and
University
of Pittsburgh School of Medicine Director
of Urological
Pittsburgh,
Pennsylvania Research
1999 – 2003 Department
of Pathology Associate
Professor w/tenure
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
1999 – 2003 Department
of Pharmacology Associate
Professor w/tenure
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
1994 – 1999 Department
of Pathology Assistant
Professor
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
1995 – 1997 Department
of Surgery Assistant
Professor
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
1995 – 1999 Department
of Medicine Assistant
Professor
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
1995 – 1999 Department
of Pharmacology Assistant
Professor
University
of Pittsburgh School of Medicine
Pittsburgh,
Pennsylvania
1997 – Present Prostate
and Urologic Cancer Program Director
of Research
University
of Pittsburgh Cancer Institute and
Co-Director
1994 – Present Prostate
and Urologic Cancer Program
University
of Pittsburgh Cancer Institute Member
1995 – Present Graduate
Faculty
University
of Pittsburgh School of Medicine Member
1996 – Present Cellular
and Molecular Pharmacology Graduate Program
University
of Pittsburgh School of Medicine Member
1997 – 1998 Cellular
and Molecular Pathology Graduate Program Member,
Executive
University
of Pittsburgh School of Medicine Steering
Committee
1998 – Present Cellular
and Molecular Pathology Graduate Program Associate
Director
University
of Pittsburgh School of Medicine
1999 - 2003 UPCI
Planning and Budget Committee Member
University
of Pittsburgh Cancer Institute
American
Society for Cell Biology 1988
– present
Society
for Basic Urologic Research 1992
– present
American
Association for Cancer Research 1993
– present
American
Urological Association – Affiliate Member 1995
– present
American
Association for Clinical Chemistry – Member 2000
– present
American
Foundation for Urologic Disease – Board of Directors 2003
- present
Caspar
Nannes Memorial Scholarship 1983
– 1987
Rutgers
Club of Washington
Henry
Rutgers Honor Scholar 1987
Rutgers
College
Cap and
Skull Honor Society, High Skull 1987
Rutgers
College
High
Honors in Microbiology 1987
Rutgers
College
First
Prize, Research, NCI National Meeting on 1989
Prostate
Cancer, Prouts Neck, Maine
Swebilius
Cancer Research Award 1992
– 1994
Yale
University School of Medicine
American
Association for Cancer Research Travel Award 1993
Special
Conference on Oncogenes and Antioncogenes
Travel
Award – Society for Basic Urologic Research Fall 1993
Symposium
Shannon
Award – National Cancer Institute, National Institutes 1995
– 1997
of Health
National
Kidney Cancer Association Young Investigator 1996
Honors Convocation
– University of Pittsburgh 1997
Society
for Basic Urologic Research/Merck Young Investigator Award 1998
Pittsburgh
Magazine, “40 under 40” Award 1999
Presenter,
American Cancer Society’s 41st Science Writers Seminar 1999
Honors Convocation
– University of Pittsburgh 2000
Chancellors
Research Award – University of Pittsburgh 2000
_________________________________________________________________________________________________
1.
Refereed
articles.
28.
Horton, M.J. and Getzenberg,
R.H. Rat Seminal Vesicle
Secretory Protein SVS-II Binds DNA with a Preference for 5’ Regulatory Regions
of Secretory Protein Genes:
Presence Among Components of the Nuclear Matrix. Journal of Andrology, 20(2): 7, 1999.
and Monitoring of
Bladder Cancer. Techniques in
Urology, 5 (4): 179-184, 1999.
of Cellular
Biochemistry. 32/33: 183-191, 1999.
In vivo Effects
of Vitamin D (calcitriol) Administration on the Normal Neonatal and
Pre-Pubertal Prostate.
Journal of
Urology, 164, 1812-1818, 2000
R. H. Clinical Usefulness of the Novel Marker, BLCA-4, for
the Detection of Bladder Cancer.
Journal of
Urology, 164: 634-639, 2000.
Evaluation of the
Effect of Spinal Cord Injury (SCI) on serum PSA levels, Urology, 56: 82-86, 2000.
48. Brunagel, G., Vietmeier, B.N., Bauer, A.J., Schoen,
R.E., and Getzenberg, R.H. Nuclear Matrix Protein Alterations
Associated with Colon Cancer Metastasis to the Liver. Clinical Cancer Research, 8: 3039-3045, 2002
55. Getzenberg,
R.H. Urine-Based Assays for Bladder Cancer. Laboratory Medicine, 34: (8) 613-617, 2003.
56. Sakamoto,
S., Yokoyama, M., Prakash, K., Tsuruha, J-I., Masamoto, S., Getzenberg, R.H. and Kakehi, Y. Development of Quantitative Detection
Assays for CYR61 as a New Marker for Benign Prostatic Hyperplasia. Journal of Biomolecular Screening, 8: No: 6: 701-711, 2003.
57. Kasai, M.,
Guerrero-Santoro, J., Friedman, R., Leman E.S., Getzenberg, R.H. and DeFranco, D. B. The Group
3 LIM Domain Protein Paxillin Potentiates Androgen Receptor Transactivation in
Prostate Cancer Cell
Lines. Cancer Research, 63: 4927-4935, 2003.
58. Kakehi, Y., Segawa,
T., Wu, X-X., Kulkarni, P., Dhir, R., and Getzenberg,
R.H. Down-regulation of Macrophage
Inhibitory Cytokine-1/Prostate Derived Factor in Benign Prostatic
Hyperplasia. The Prostate, 59: 351-356, 2004.
59. Dhir, R., Vietmeier, B., Arlotti, J., Acquafondata,
M., Landsittel, D. Getzenberg, R.H. Early
Identification of
Individuals with Prostate Cancer in “Negative Biopsies”. J. of Urology, 171:1419-1423, 2004.
60. Guzey,
M., Arlotti, J., Acquafondata, M., Jukic, D., Dhir, R., and Getzenberg, R.H. Increased Apoptosis of Periprostatic
Adipose Tissue in VDR Null Mice. Journal of Cellular Biochemistry, in press,
2004.
61. Guzey, M., Luo
J. and Getzenberg, R.H. Vitamin D3 Modulated Gene
Expression Patterns in Primary Prostate
Normal and Cancer Cells. Journal
of Cellular Biochemistry, 93:271-285,
2004.
62. Shah, U.S., and
Getzenberg, R.H. Fingerprinting the Diseased Prostate:
Association Between BPH and Prostate
Cancer. Journal of Cellular
Biochemistry, 91:161-169, 2004.
63. Brunagel,
G., Schoen, R.E., and Getzenberg,
R.H. Colon Cancer Specific
Nuclear Matrix Protein
Alterations
in Human Colonic Adenomatous Polyps.
Journal of Celluar Biochemistry, 91:
365-374, 2004.
64. Van
Le, T-S.T., Myers, J., Konety, B.R., Barder, T., and Getzenberg, R.H.
Functional Characterization of
the Bladder Cancer Marker, BLCA-4.
Clinical Cancer Research, 10: 1384-1391,
2004.
65. Shah, U.S.,
Arlotti, J., Dhir, R., Lu, S., Pirozzi, G., Prakash, K., and Getzenberg, R.H. Androgen Regulation of JM-27 is Associated with
the Diseased Prostate. Journal of
Andrology, 25: 618-624, 2004.
66. Van Le, T-S.T.,
Miller, R., Barder, T., Babjuk, M., Potter D.M., and Getzenberg, R.H. A
Highly Specific
Urine-Based Marker of Bladder Cancer.
Clinical Cancer Research, submitted, 2004.
67. Chen,
J., Davies, B., and Getzenberg, R.H. Diagnostic Markers of Renal Cell
Carcinoma. Journal of Urology, submitted,
2004.
68. Myers, J.M.,
Landsittel, D., and Getzenberg, R.H. Utilization of the Novel Marker,
BLCA-1, for Detection
of Bladder Cancer. Journal of
Urology, submitted, 2004.
69.
Perlmutter, M.A., Dhir, R., Acquafondata, M.B., Hrebinko, R.L. and Getzenberg, R.H. Immunohistochemical
Analysis of Ki-67, Cyclin B1, CENP-F and MCM7 in Human Bladder Cancer. Urologic Oncology, submitted, 2004.
70. Sakamoto,
S., Yokoyama, M., Zhang, X., Prakash, K., Nagao, K., Hatanaka, T., Getzenberg, R.H., and Kakehi, Y. Increased Expression of CYR61, an
Extracellular Matrix Signaling Protein, in Human Benign Prostatic Hyperplasia and Its
Regulation by Lysophosphatidic Acid.
Endocrinology, 145:(6)
2929-2940, 2004.
71. Davies,
B., Chen, J., Leiras, C., Modugno, F.M., Landsittel, D., Dhir, R., Nelson, J.,
and Getzenberg, R.H. Dimming the Future of Survivin
as a Bladder Cancer Biomarker: The Emerging Role of the Prostate. JAMA, submitted, 2004.
72. Paul, B., Dhir, R., Landsittel, D., Hitchens, M.R., and Getzenberg, R. H. Detection
of Prostate Cancer with a Blood-Based Assay for EPCA. Nature Medicine, submitted, 2004.
73. Ouyang,
D.L., Chen, J.J., Getzenberg, R.H.,
and Schoen, R.E. Non-Invasive
Testing for Colorectal Cancer: A Review.
American J. of Gastroenterology, submitted, 2004.
74. Minnery,
C., and Getzenberg, R.H. BPH Cell Viability and Modulation of
JM-27 by Doxazosin and Ibuprofen.
Journal of Urology, submitted, 2004.
2.
Books,
Chapters and Reviews.
1. Getzenberg, R.H., and Coffey, D.S. Tissue Specificity and Cell Death are
Associated with Specific Alterations in Nuclear Matrix Proteins, In: Karr, J.P., Tindall, D.J., Coffey,
D.S., and Smith, R.G. (eds) Molecular and Cellular Biology of Prostate Cancer,
Plenum Press, New York, pg 1-13, 1989.
2. Pienta, K.J., Murphy, B.C., Getzenberg, R.H., and Coffey, D.S. The Tissue Matrix and the Regulation of
Gene Expression in Cancer Cells.
Advances in Molecular and Cellular Biology, 7:131-156, 1993.
3. Getzenberg, R.H. Book Review of Essential Endocrinology. The Physiologist, 409, 1996
4. Getzenberg, R.H. The Tissue Matrix:
Cell Signaling and Hormone Regulation. In: Bittar, E.E. and Bittar, N. (eds)
Principles of Medical Biology, JAI Press, Inc., Greenwich, CT, 10B:643-662, 1997.
5. Konety,
B.R. and Getzenberg, R.H. Novel Therapies for Advanced Prostate
Cancer. Seminars in Urologic
Oncology, 15(1):33-42, 1997.
6. Horton,
M.J. and Getzenberg, R.H. The Role
of the Nuclear Matrix in Tissue Specific Gene Expression. In: Getzenberg, R.H. (ed.) Cell
Structure and Signalling, JAI Press Inc., Greenwich, CT, 185-206, 1997.
7. Getzenberg, R.H. Telomerase, Aging and Cancer. AUA News,
2(4):10, 1997.
8. Getzenberg, R.H. Vitamin D and Normal Prostate Growth
and Differentiation. Nutrition
Report, 15(4):25,32, 1997.
9. Uskokovic,
M.R., Trump, D.L., Getzenberg, R.H.,
and Johnson, C.S. Anticancer
Activity of Vitamin D Analogs. In:
Holick, M.(ed) Vitamin D Physiology, Molecular Biology, and Chemical
Application, Humana Press, Totowa, NJ, in press.
10. Konety,
B.R., Johnson, C.S., Trump, D.L., Getzenberg,
R.H. Vitamin D in the
Prevention and Treatment of Prostate Cancer. Seminars in Urologic Oncology, 17:77-84, 1999.
11. Getzenberg, R.H.,
Reviewer - Unweaving the Rainbow: Science, Delusion, and the Appetite for
Wonder, Author, Richard Dawkins. Oncology Times, 1999.
12. Getzenberg, R.H. The Nuclear Matrix and
Cytoskeleton. The Role of the
Nuclear Matrix and Cytoskeleton in Cancer, In: Chung, L. W. K., Isaacs, W. B.
and Simons, J. W. (eds) Prostate
Cancer: Biology, Genetics, and the New Therapeutics. Humana Press, Totowa, NJ, 2000.
13. Lokeshwar, V.B.
and Getzenberg, R.H. Voided Urine Markers. Lerner, S.P., Schoenberg, M., Sternberg, C.
(Eds): Textbook of Bladder Cancer.
London: T& F-Informa, 2005 (in preparation),
3.
Published
abstracts.
Georgia,
2000.
84. Nguyen,
T-S.T., Konety, B.R., Myers, J.M., and Getzenberg,
R.H. A Novel Highly Specific
and Sensitive Urine-Based Assay for the Detection of Bladder Cancer. American Association for Clinical
Chemistry, La Jolla, CA, 2002.
87. Shah,
U.S. and Getzenberg, R.H. Identification of a Potential Growth
Regulatory Gene Demonstrating a “Field Effect” In Prostate Cancer. American Association for Cancer
Research, San Francisco, CA, 2002
89. Nguyen,
T-S.T., Konety, B.R., Myers, J.M., and Getzenberg,
R.H. A Novel Highly Specific
and Sensitive Urine-Based Assay for the Detection of Bladder Cancer. XVIIth Congress of the European
Association of Urology, Birmingham, England, 2002.
90. Björnsson,
Björn L., Sylvester, R., Getzenberg,
R.H., Oosterlinck, Willem and Goebell, Peter, J. Comprehensive Analysis of Urine-Based Markers for Bladder
Cancer – The Proposed Multicenter Urothelial Neoplasia Detection (MUND)
Study. 2nd
International NCI-EORTC Meeting on Cancer Diagnostics, Washington, D.C., 2002.
91. Getzenberg, R.H.,
Davido, T., Konety B.R., Van Le, T-S.T.
A Highly Specific and Senstitive Urine-Based Assay for the Detection of
Bladder Cancer. Oak Ridge
Conference – Cancer Detection and Monitoring: The Next Generation of Diagnostic
Tools. La Jolla, California, 2002.
92. Kulkarni,
P., Pirozzi, G., Elashoff, M., Waga, I., Munger, W., Dhir, R., Kakehi, Y., and Getzenberg, R.H. Genetic Similarity of BPH from
Individuals with Symptoms and Those with Prostate Cancer. American Urological Association, Annual
Meeting. Orlando, Florida, 2002.
93. Kulkarni,
P., Pirozzi, G., Elashoff, M., Waga, I., Munger, W., Dhir, R., Kakehi, Y., and Getzenberg, R.H. Differentiating Symptomatic and
Asymptomatic BPH: JM-27. American
Urological Association, Annual Meeting.
Orlando, Florida, 2002.
100. Myers, J.M.,
Van Le, T-S.T., and Getzenberg, R.H. Characterization of Nuclear Matrix
Changes Involved in Bladder Cancer
Progression. International Bladder
Symposium, Arlington, VA, 2003.
101 Muscatello,
M., Getzenberg, R.H. Development of an Intelligent Polymerized Crystalline Colloidal Array for
the Detection of Cancer Signature Proteins. 35th Central Regional Meeting of the American
Chemical Society in the Symposium on Analytical Chemistry. Pittsburgh, PA, 2003.
102 Muscatello,
M., Getzenberg, R.H. Development of an In-vivo Sensing Technology for Cancer Signatures. 2004 Pittsburgh Conference. Pittsburgh, PA, 2004.
103. Dhir, R.,
Vietmeier, B., Arlotti, J., Acquafondata, M., Landsittel, D., Masterson, R.,
and Getzenberg, R.H. Identification of Individuals with
Prostate Cancer by Examination of “Negative Biopsies”. American
Urological Association, Annual Meeting.
San Francisco, CA, 2004.
104.
Van Le, T-S.T., Miller, R., Barder, T., Babjuk, M., Potter, D.M., and Getzenberg, R.H. BLCA-4, A Highly Specific Marker
Urine-Based Marker of Bladder Cancer.
American Urological Association, Annual
Meeting. San Francisco, CA, 2004.
105.
Chen, J.J., and Getzenberg, R.H. Using Nuclear Matrix Protein, RCCA-5,
as Biomarker for Renal Cell Carcinoma. Americal Urological Association, Annual
Meeting. San Francisco, CA, 2004.
-------------------------------------------------------------------------------------------------------------------------------
PROFESSIONAL ACTIVITIES
TEACHING:
1994 "The
Role of Nuclear Structure in Gene Regulation and Cancer"
Medical Oncology Grand Rounds, University of Pittsburgh Medical Center
Pittsburgh, PA
1994 "The
Role of the Nuclear Matrix in Prostate Cancer"
Urology Grand Rounds, University of Pittsburgh Medical Center,
Pittsburgh, PA
1994–Present Organized bi-monthly research conference for
investigators, fellows and students with
interests in prostate and GU cancers.
1994–Present Cancer
Research and the Pittsburgh Cancer Institute
Presented a weekly orientation for local High School students sponsored
by the LHAS.
1994- 1995 Sponsored Directed Research (Course #
Bioscience 1903) for undergraduate Jeff Butcher entitled, "Examination of
Vitamin D Receptors on the Nuclear Matrix"
1995 Sponsored
Directed Research (Course # Bioscience 1903) for undergraduate Tisha Nardozza
entitled, "Association of Transcription Factors with the Nuclear
Matrix"
1995 "The
Role of the Nuclear Matrix in Gene Regulation and Cancer"
Department of Pharmacology Seminar, University of Pittsburgh Medical
Center
Pittsburgh, PA
1995 "The
Role of the Nuclear Matrix in Gene Regulation and Cancer"
Human Genetics Seminar - HUGEN 2025,
University of Pittsburgh
Pittsburgh, PA
1995
Pittsburgh Cancer Institute
Orientation
1995 Lectured in Department of Pharmacology Graduate
Course, Cancer Pharmacology
1995 Facilitator
for Medical Student course Cancer
Pharmacology
1995
Comprehensive Examination Committee,
Edwina C. Lerner
Department of Pharmacology
1995- 1996 Training
of Dr. Badrinath R. Konety, Urology Resident
Laboratory Research
1996–Present Thesis
Committee, Yuting Tang
Department of Biology - Donald DeFranco, Thesis Advisor
1996 Pharmacology
Course
Problem Based Learning Session Leader
1996 Lectured in Department of Pharmacology Graduate
Course, Cancer Pharmacology
1996 Lectured
in "From Bench to Bedside”-Frontiers in Cancer Research
University of Chicago
1996 Integrated
Life Sciences - Neoplastic Disease Course (2/96-3/96)
1996 Comprehensive
Examination Committee, Marni Brisson Department of Pharmacology
1996 Training
of Dr. Ajay K. Nangia, Urology Resident
Laboratory Research
1996 "Recent
Advances in Prostate and Bladder Cancer"
Urology Grand Rounds, University of Pittsburgh Medical Center,
Pittsburgh, PA
1996
Laboratory Research Rotation,
Lei Zheng, Department of Pathology, Graduate Student
1996 Training
of Amy Abdulovic, High School Student Intern
1997 Lectured
in Graduate Biochemistry Course, West Virginia University, Department of
Biochemistry, "Nuclear Matrix and Regulation"
1997 Pharmacology
Course
Problem Based Learning Session Leader
1997
UPCI, Biologic Therapy Program,
Biologic Therapy and Transplantation Research
Colloquia, "Novel Approaches to Prostate and Bladder Cancer: Nuclear
Matrix and
Vitamin D"
1997 Cancer
Research, National Defense University, Industrial College of the Armed Forces,
University of Pittsburgh Cancer Institute
1997 Faculty,
1997 American Urological Association Annual Meeting, "Understanding
Molecular Techniques and Their Applications to Urology", New Orleans, LA
1997 Facilitator
for Medical Student Pharmacology
Conference on Host Defenses
1997 Lectured
in Department of Pharmacology Graduate Course, Cancer Pharmacology
1997 Hematology/BMT
Research Seminar. "Novel Approaches to Prostate and Bladder Cancer:
Nuclear Matrix and Vitamin D"
1997 Judge
- 8th Annual Department of Pathology Research Presentations
1997 Cancer
and Cancer Research, Visiting Nurses from Japan, University of Pittsburgh
Cancer Institute
1997 Presented
to UPCI Council Members
1997 "The
Nuclear Matrix and Cancer"
Medical Oncology Grand Rounds, University of Pittsburgh School of
Medicine Pittsburgh, PA
1997 "Cancer
Associated Nuclear Matrix Proteins"
Pathology Research Seminar, University of Pittsburgh School of Medicine,
Pittsburgh, PA
1997-1999 Thesis
Committee, Jimin Liu
Department of Biology - Donald DeFranco, Thesis Advisor
1997 Cancer
and Cancer Research, Nursing Students, University of Pittsburgh Cancer
Institute
1997-1998 Thesis
Committee, Jen-Tzer Gao
Department
of Pathology - Michael J. Becich, Thesis Advisor
1997–1998
Supervised Undergraduate Research Project of Kyle Fisher
1998 Pharmacology
Course
Problem Based Learning Session Leader
1998 Facilitator
for Medical Student Pharmacology Conference on Host Defenses
1998-Present Prostate
Cancer and Cancer Metastasis Lectures of School of Medicine Graduate Course,
"Cancer Biology", University
of Pittsburgh School of Medicine
1998 Lectures
of School of Medicine Course, "Tissue Structure, Growth and
Function".
University of Pittsburgh School of
Medicine
1998 Cancer
Research, National Defense University, Industrial College of the Armed Forces,
University of Pittsburgh Cancer Institute
1998 Faculty,
1998 American Urological Association Annual Meeting, "Understanding
Molecular Techniques and Their Applications to Urology", San Diego, CA
1998-2000 Preceptor for Dr. Badrinath R.
Konety, American Foundation for Urologic Disease and Foundation for Strategic
Bladder Research Scholar
1998-Present Thesis
Committee, Jennifer Guerrero
Department of Biology - Donald DeFranco, Thesis Advisor
1998-2000 Thesis
Committee, Mark Whitmore
Department of Pharmacology - Leaf Huang, Thesis Advisor
1998 Summer
Internship, Amy Abdulovic Grove City College
1998 Comprehensive
Examination Committee, Yadi Tan
Department of Pharmacology
1998 Research
Rotation, M.D., Ph.D. Program Jared Muenzer
1998
Lectured in the Medicine, Ethics
and Society Course, School of Medicine
1998
Presentation on Medical Ethics
to M.D., Ph.D. Students, University of Pittsburgh School of Medicine
1998-Present Co-Director
and Lecturer Neoplasia and Neoplastic Diseases Course, Medical Students, University of
Pittsburgh School of Medicine
1998-1999 Thesis Committee, Michael Gray
Molecular Genetics and Biochemistry –
Bo Liu, Thesis Advisor
1998-Present Faculty
Advisor, Interdisciplinary Graduate Program
Eddy Leman
1999 “New Marker to Detect Bladder Cancer”.
Healthsouth Harmarville Rehabilitation Hospital,
Rehabilitation Mini-Grand Rounds,
Harmarville, PA.
1999 Lectured
on Prostate Biology in “Tissue Structure, Growth and Function”.
University of Pittsburgh School of Medicine.
1999
Pharmacology Course
Problem Based Learning Session Leader
1999
Training of Kate Dougherty – High School Intern
1999 Research
Rotation, Interdisciplinary Graduate Program – Matthew Wilson
1999 Lectured
in the Medicine Ethics and Society Course, School of Medicine
1999 Lectured
in the Foundations of Biomedical Science, School of Medicine
1999 "The
Role of the Nuclear Matrix in Gene Regulation and Cancer"
Pharmacology Research Seminar,
University of Pittsburgh School of Medicine, Pittsburgh, PA
1999 Research
Rotation, Interdisciplinary Graduate Program – Andrew Lepisto
1999
“Cancer and Cancer Research”
Grove City College, Grove City, PA
2000 Lectured
on Prostate Biology in “Tissue Structure, Growth and Function”.
University of Pittsburgh School of
Medicine.
2000 “Current
Advances in Bladder Cancer”
Armstrong County Memorial Hospital – Tumor Board
Kittanning, PA
2000
Summer Internship, Amy Abdulovic Grove City College
2000 Summer
Internship, Roger Bartollota
2000 Course
Director/Integrated Life Sciences Course/Neoplasia and Neoplastic Disease –
University of Pittsburgh
2000
Pathobiology Course – Lecturer
“Nuclear Controls and Transcription Regulation in
Prostate Cancer”
2000-2002 Training
of Tracy Davido, Medical Student IV
Laboratory Research
2000-2002 Training
of Janey Whalen, Ph.D.
Postdoctoral Fellow
2000
Lectured in the Medicine Ethics and Society Course, School of Medicine
2000
Research Rotation, Jared
Muenzer, Medical Student IV
2000-2003
Gisela Brüenagel, M.D.
Postdoctoral Fellow-Feodor Lynen Fellowship Award
2000-2001 Research
Rotation, Interdisciplinary Graduate Program – Lana Hanford
2000 Lectured
in the Foundations of Biomedical Science, School of Medicine
2000
Lectured in the Medicine Ethics and Society Course, School of Medicine
2000
Course Director/Integrated Life
Sciences Course/Neoplasia and Neoplastic Disease
University of Pittsburgh
2001 Lectured
on Prostate Biology in “Tissue
Structure, Growth and Function”
University
of Pittsburgh School of Medicine
2001-Present Interdisciplinary Graduate Program /Thesis
Advisor/Molecular Pharmacology Training Program
Julie Myers
2001 Thesis
Committee,
Department of Pathology – Lei Zheng, Michael J. Becich, Thesis Advisor
1999-2003 Interdisciplinary
Graduate Program/Thesis Advisor – Eddy Leman
2001 Summer
Internship, Pittsburgh Tissue Engineering Initiative, Inc. – Michael Madigan
2001 Summer
Undergraduate Research Program – Elizabeth Pino
2001 Summer
Internship, Amy Abdulovic / Grove City College
2001-2003 Training
of Uzma Shah, Ph.D.
Postdoctoral
Fellow
2001 Cancer
Biology and Therapeutics Course - Lecturer
“Biology of Transformation: Invasion and Metastasis”
Departments
of Pathology & Pharmacology – University of Pittsburgh
2001 Pathobiology
Course – Lecturer
“Nuclear Controls and Transcription
Regulation in Prostate Cancer”
2001 Lectured
in the Foundations of Biomedical Science, School of Medicine
2001 Lectured
in Human Genetics Seminar, School of Medicine
“Novel
Approaches to Urologic Diseases: Cancer and BPH”
2002 Thesis
Committee,
Cellular and Molecular Pathology
Training Program – Lei Zheng,
Michael J. Becich,
Thesis Advisor
2001
Lectured in Integrated Life
Sciences Course/Neoplasia and Neoplastic Disease – University of Pittsburgh
2002-2003 Training
of Meral Guzey, Ph.D.
Postdoctoral
Fellow
2002 - 2003 Summer
Internship – Kristin Stolarczyk / Penn State University
2001-2002
Research Rotation,
Interdisciplinary Graduate Program – Marie Aquilano
2002
Summer Internship – Michael
Madigan
2002
Pittsburgh Development Center Seminar Series – Magee-Womens Research
Institute
“Genomic and Proteomic Approaches to Urologic Cancers
and Benign Diseases – University of Pittsburgh
2002 Lectured
in the Foundations of Biomedical Science, School of Medicine
2002 Thesis
Committee,
Cellular
and Molecular Pathology Training Program - Jeffrey Chou
2002 Thesis
Committee, Robert H. Getzenberg, Thesis Advisor
Cellular and Molecular Pathology Training Program, Eddy
Leman
2002 Summer
Research Undergraduate Program – Henry Richard Johnston, IV
Research
Rotation, Interdisciplinary Graduate Program
2002 Summer
Undergraduate Research Program – Matthew Germinaro
Research
Rotation, Interdisciplinary Graduate Program
2002 Summer
Undergraduate Research Program – Elizabeth Pino
Research
Rotation, Interdisciplinary Graduate Program
2002 Summer
Graduate Research Program/Academic Advisor – Peter McDonald
Research
Rotation, Interdisciplinary Graduate Program
2002
Lectured in Integrated Life
Sciences Course/Neoplasia and Neoplastic Disease – University of Pittsburgh
2002 Cancer
Biology and Therapeutics Course - Lecturer
“Biology of Transformation: Invasion and Metastasis”
Departments
of Pathology & Pharmacology – University of Pittsburgh
2002
Lectured in the Foundations of Biomedical Science, School of Medicine
2002 Pathobiology
Course – Lecturer
“Nuclear Controls and Transcription
Regulation in Prostate Cancer”
2002-2003 Research
Rotation, Interdisciplinary Graduate Program – Sheila Roberts
2003- Present Thesis
Committee
Cellular and Molecular Pathology
Training Program
Katherine
Bright
2003-Present Training
of Manimalha Balasubramani, Ph.D.
Postdoctoral
Fellow
2003- Present Thesis
Committee – Sourabh Kharait
Cellular and Molecular Pathology
Training Program - Alan Wells, Thesis Advisor
2003
Summer Research Undergraduate
Program – Alison Atwood
Research
Rotation, Interdisciplinary Graduate Program
2003 Summer
Research Undergraduate Program – Miranda Sarachine
Research
Rotation, Interdisciplinary Graduate Program
2003 Research
Rotation, Interdisciplinary Graduate Program – Jason D’Antonio
2003-2004 Training
of Joseph Chen, Medical Student
Laboratory Research
2003 Cancer
Biology and Therapeutics Course - Lecturer
“Biology of Transformation: Invasion and Metastasis”
Departments
of Pathology & Pharmacology – University of Pittsburgh
2003 Lectured
in the Foundations of Biomedical Science, School of Medicine
2003 Medical
Student Research Rotation, Mark Perlmutter
2003 - Present Thesis
Committee
Cellular
and Molecular Pathology Training Program – Siva Raja
2003 Comprehensive
Examination Committee/GSR Department of Environmental and Occupational Health
- Cathy Thomas
2002-2003 Preceptor
for Dr. Uzma Shah, American Foundation for Urologic Disease and Research
Scholar
2003 - 2004 Training
of Cynthia Hoffman, PharmD.
Research
Associate
2004 Pharmacology
Seminar
“Genomic
and Proteomic Approaches to Urologic Cancers and Benign Diseases”
Department
of Pharmacology – University of Pittsburgh School of Medicine
2004
Urology Residency Training –
Research Rotation
Benjamin Davies, M.D.
2004 - Present Thesis
Committee - Amanda Boehm
Cellular and Molecular Pathology Training Program -
Janey Whalen, Thesis Advisor
2004 - Present Thesis
Committee – Pamela L. Beatty
Immunology
Training Program - Olja Finn, Thesis Advisor
2004 - Present Thesis
Committee – Jason D’Antonio
Cellular
and Molecular Pathology Training Program – Beth Pflug, Thesis Advisor
2004 Research
Rotation, Grant Cannon
2004 Summer
Research Undergraduate Program – Robin Cline
Research
Rotation, Interdisciplinary Graduate Program
2004 Summer
Research Undergraduate Program – Ellen Leffler
Research
Rotation, Interdisciplinary Graduate Program
2004 Urology
Residency Training – Research Rotation
Glenn Cannon, M.D.
2004 Cancer
Biology and Therapeutics Course - Lecturer
“Biology of Transformation: Invasion and Metastasis”
Departments
of Pathology & Pharmacology – University of Pittsburgh
2004 Thesis
Committee – Greg Gan
Molecular
Pharmacology Program – Ferrucio Galbiati Thesis Advisor
2004 Research
Rotation, Interdisciplinary Biomedical Graduate Program – Martha Milton
RESEARCH:
1. Grant
Support
Active
Grant Number Role
in Project & Years Source
(Funded)___ Grant
Title Percentage
of Effort Inclusive Amount
2 RO1 CA082522-06 Characterization
of the Bladder Principal
Investigator 2000-2005 $1,154,679
(NIH) Cancer
NMP, BLCA-4 11.7%
1 P01 HD39768-01 Collaborative
Urologic Principal
Investigator 2001-2006 $4,981,551
(NIH) Research
In Spinal Cord Injury- 10%
Project 3-Biomarkers of Bladder
Cancer in SCI Individuals
Tessera Inc. Sponsored
Research Agreement Principal Investigator 2002-2004 $647,935
0%
1 R13 CA/DK97015 Prouts
Neck Prostate Cancer Principal
Investigator 2002-2006 $213,389
(NCI) Meeting 0%
NIH-UO1DK063593 MTOPS
Biomarker Unit at Principal
Investigator 2002-2005 $1,270,215
the
University of Pittsburgh 25%
NIH-R01-CA96105-01 Specific
Biomarkers in Bladder Principal
Investigator 2002-2006 $982,642
Cancer
Prevention 10%
5P 30 CA47904-13 Prostate
and Urologic Cancer Program
Co-Director 1999-2004 $3,070,434
(NIH) Program-UPCI
Cancer Center 5%
Core
Grant
Pfizer Inc. Effects
of Doxazosin on
Modulation
of Novel Genes
Assoc.
with Symptomatic BPH Principal
Investigator 2004-2005 $15,000
NIH-R41 CA107448 Novel
Protein Marker for Co-Investigator 2004-2005 $100,000
Prostate
Cancer Detection 5%
1 K12 DK02656-01 Physicians
and Scientist Co-Investigator 1999-2004 $896,805
1 T32 DK07774-01 Training
Program in Urologic 5% $484,795
(NIH) Research
N0I-CN-75018 A
Phase II Clinical Trial of Co-Investigator 1996-2004
$417,835
(NIH) Anti-Androgen
and 5-alpha 0%
Reductase
Inhibitors in Patients
With
Prostate Cancer.
Administration
in the Period
Prior
to Radical Prostatectomy
(Presurgical
Period). Modulation
of
Surrogate Endpoint Biomarkers
(Seb)
DAMD3058093 A
Novel Approach in Prostate Co-Investigator 2001-2004
$541,710
(DOD) In
Prostate Cancer Therapy 8%
N01-CO-17016-32 Development
of an in-vivo Co-Investigator 2001-2004 $1,776,806
(NIH) Sensing
Technology for the 10%
Development
of Biomolecular
Sensors
Previous
Grant Number Role
in Project & Years Source
(Funded) Grant
Title Percentage
of Effort Inclusive Amount
1R55 CA/OD65463 Shannon
Award Principal
Investigator 1995-1997 $50,000
(NIH)
National Kidney Evaluation
of Nuclear Matrix Principal
Investigator 1996-1997 $20,000
Foundation of Protein
Markers in Renal
W. Penn Cell
Carcinoma
Comp. Medical Bladder
Cancer Associated Principal
Investigator 1996-1997 $25,000
Research Fund Nuclear
Matrix Alterations
National Kidney The
Clinical Utility of Renal Principal
Investigator 1996-1997 $30,000
Cancer Assoc. Cell
Carcinoma Associated
Nuclear
Matrix Proteins
Matritech Sponsored
Research Principal
Investigator 1996-1997 $100,000
Agreement
Demeter Demeter
Bio Technologies Ltd. Principal
Investigator 1997-2000
$280,000
NIH-1RO3 HD35878 Spinal
Cord Injury and Principal
Investigator 1998-2000
$150,500
Bladder
Cancer Detection 10%
Lilly and Co. The
Study of LY353381 Principal
Investigator 1998-2000
$8,140
In
Prostate Cancer
NIH-1R29 CA65463 Prostate
Cancer Associated Principal
Investigator 1996-2001
$528,299
Nuclear
Matrix Alterations 25%
TAP Pharm. Sponsored
Research Principal
Investigator 1999-2002 $128,565
Agreement
GeneLogic Sponsored
Research Principal
Investigator 1999-2002 $923,624
Agreement
NIH-1 R13 CA091916 FASEB
Conference: Nuclear Conference
Co-Chair 2001-2001 $36,000
Structure
and Cancer 0%
CaP CURE Induction
of an Immune Co-Investigator 1996-1997 $100,000
Response
to Normal Prostate
Antigens
as an Immunotherapeutic
Strategy
for Prostate Cancer
DOD Role
of Extracellular Matrix Consultant 1997-2000
And
Nuclear Structure
Interactions
in Gene Expression
And
Breast Cancer: Use of a 3D
Culture
Model of Human Mammary
Tumorigenesis
University of Chemoprevention
of Urinary Consultant 2000-
2001 $35,000
Alabama at Bladder
Cancer by NSAIDS
Birmingham
Eichrom Tech., Inc. Sponsored
Research Agreement Principal
Investigator 1999-2003
$254,000
0%
Pending
Grant Number Role
in Project & Years Source
(Funded) Grant
Title Percentage
of Effort Inclusive Amount
NIH-R01CA098707 Characterization
of the Bladder Principal
Investigator 2005-2010 $1,500,000
Cancer
NMP 25%
NIH-R01 DK069401 Characterization
of a Stromal Principal
Investigator 2004-2009 $1,664,009
Specific
Marker of BPH 25%