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Asian Journal of Andrology (2009) 11: 209-214. doi: 10.1038/aja.2008.1; published online 5 January 2009.
Evaluation of erectile function after urethral reconstruction: a prospective study
Hong Xie1, Yue-Min Xu1, Xiao-Lin Xu1, Yin-Long Sa1, Deng-Long Wu1 and Xin-Chi Zhang1
1 Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China
Correspondence: Dr Yue-Min Xu, Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yi Shan Road, Shanghai 200233, China. Fax: +86-21-64083783 E-mail: xuyuemin@263.net
Received 14 March 2008; Revised 2 June 2008; Accepted 4 August 2008; Published online 5 January 2009.
| Abstract |
We conducted a prospective study of erectile dysfunction (ED) after urethral reconstructive surgery, using the 5-item International Index of Erectile Function (IIEF-5), the Sexual Life Quality Questionnaire (SLQQ) and the Quality of Life Questionnaire (QoLQ). Between January 2003 and July 2007, 125 male patients with urethral strictures underwent urethroplasty, and pre- and post-surgery erectile function was assessed using these three questionnaires. A formula to predict the probability of ED after urethroplasty was derived. At 3 months post-operatively, there was a significant decrease in IIEF-5 (16.57 ± 7.98) and SLQQ scores (28.71 ± 14.84) compared with pre-operative scores (P < 0.05). However, the IIEF-5 scores rebounded at 6 months post-operatively (17.22 ± 8.41). Logistical regression analysis showed that the location of the urethral stricture, the recurrence of strictures and the choice of surgical technique were predictive of the post-operative occurrence of ED. This study identified the clinical risk factors for ED after urethroplasty. Posterior urethral stricture and end-to-end anastomosis were found to have a strong relationship with erectile function. The logistical model derived in this study may be applied to clinical decision algorithms for patients with urethral strictures.
Keywords: erectile dysfunction, urethroplasty, urethral stricture |
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