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Abstract

Asian Journal of Andrology (2009) 11: 379–384. doi: 10.1038/aja.2008.61; published online 6 April 2009.

The ejaculatory duct ectopically invading the bladder with multiple congenital malformations of the homolateral urogenital system: a report of a rare case and an embryological review

Feng Wang1,*, Hong-Fei Wu2,* and Jie Yang2

1 Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
2 Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

Correspondence: Correspondence: Jie Yang, M.D., Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Fax: +86-25-8372-4440 E-mail: yj197912@163.com

* The two authors contributed equally to this article.

Received 20 June 2008; Revised 15 December 2008; Accepted 29 December 2008; Published online 6 April 2009.

Abstract
We report a rare case of a left ejaculatory duct that allotropically protrudes towards or invades the left vesicle triangular area with its dead end. The patient simultaneously exhibited multiple congenital malformations of the homolateral urogenital system, such as absence of the left kidney, dysplasia and allotopia of the left seminal vesicle, absence of the left ureterostoma, separation between the left testis and the epididymis tail, and maldevelopment of the left testis. According to all clinical and laboratory evidence, the case represented a new syndrome, which we named Wuyang's syndrome. It involved a rare phenomenon in embryonic development; the dysplastic proximal vas precursor, having intruded into a common mesonephric duct and accidentally encroaching on the ureteric bud position, resulted in the absence or dysplasia of the homolateral urinary tract and ectopic invasion of the bladder by the homolateral seminal tract.

Keywords: common mesonephric duct, proximal vas precursor, ureteric bud, urogenital system

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