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Asian Journal of

nature publishing group Andrology

Volume 13 Number 5 September 2011

www.asiaandro.com; www.nature.com/aja

RESEARCH HIGHLIGHT

651 The skeleton gets a (reproductive) life

Charles M Allan and David J Handelsman

653 The significance of testosterone for fair participation of the female sex in competitive sports

Louis Gooren

655 Prostate-specific antigen (PSA) screening: has the pendulum swung too far?

Jason M Phillips and E David Crawford

657 Highlights on FOXO3 and tumor-associated dendritic cells in prostate cancer

Kwong Y Tsang and James L Gulley

659 Highlights from the prostate cancer genome report

Shyh-Han Tan, Gyorgy Petrovics and Shiv Srivastava

661 DNA methylome and the complexity of discovering prostate cancer biomarkers

Shahriar Koochekpour

663 Abiraterone acetate for prostate cancer: a new era of hormonal therapies

Emmanuel S Antonarakis

665 Green spermatozoa illuminate a 30-year-old model: sperm–egg adhesion involves intra-acrosomal proteins

Steve Tardif

COMMENTARY

667 Does digit ratio (2D:4D) predict penile length?

Denise Brooks McQuade c see also p 710

OPINION

669 Where medicine meets the boundaries of manhood and womanhood

Louis Gooren

PERSPECTIVE

673 TRP channels in prostate cancer: the good, the bad and the ugly?

Dimitra Gkika and Natalia Prevarskaya

677 Can we grow sperm? A translational perspective on the current animal and human spermatogenesis models

Kirk C Lo and Trustin Domes

683 Current paradigms and evolving concepts in metastatic castration-resistant prostate cancer

Sumanta Kumar Pal and Oliver Sartor

REVIEW

690 The role of antioxidant therapy in the treatment of male infertility: an overview

Francesco Lombardo, Andrea Sansone, Francesco Romanelli, Donatella Paoli, Loredana Gandini and Andrea Lenzi

698 Is XMRV a causal virus for prostate cancer?

Zhen-Zhen Zhang, Bao-Feng Guo, Zhuang Feng, Ling Zhang and Xue-Jian Zhao

ORIGINAL ARTICLE Reproduction

702 Effects of di-n-butyl phthalate on male rat reproduction following pubertal exposure

Ai-Mei Bao, Xiao-Ming Man, Xue-Jiang Guo, Hui-Bin Dong, Fu-Qiang Wang, Hong Sun, Yu-Bang Wang, Zuo-Min Zhou and Jia-Hao Sha

710 Second to fourth digit ratio: a predictor of adult penile length

In Ho Choi, Khae Hawn Kim, Han Jung, Sang Jin Yoon, Soo Woong Kim and Tae Beom Kim c see also p 667

715 Trends in the incidence of cryptorchidism and hypospadias of registry-based data in Korea: a comparison

between industrialized areas of petrochemical estates and a non-industrialized area Sae Chul Kim, Su Kyoung Kwon and Yeon Pyo Hong

Prostate Disease

719 Younger patients have poorer biochemical outcome after radical prostatectomy in high-risk prostate cancer

Sung Kyu Hong, Jung Soo Nam, Woong Na, Jong Jin Oh, Cheol Yong Yoon, Chang Wook Jeong, Hyun June Kim, Seok-Soo Byun and Sang Eun Lee

724 Efficacy and cost analysis of transrectal ultrasound-guided prostate biopsy under monitored anesthesia

Sung Gu Kang, Bum Sik Tae, Sam Hong Min, Young Hwii Ko, Seok Ho Kang, Jeong Gu Lee, Je Jong Kim and Jun Cheon

Contents

Di-n-butyl phthalate (DBP) is an in-dustrial chemical used primarily as plasticizers and is present in a wide variety of products in our daily life, including building materials, medical devices, and particularly food pack-aging. In the article of Bao et al. on pages 702-709, when male rats were treated with low doses of DBP which are similar to environmental exposure doses, the expression levels of pro-teins participating in spermatogenesis have changed although no obvious morphological changes appeared. So it is also an endocrine-disrupting chemical that has the potential to affect male reproduction. Therefore, now whether to add DBP in these industrial products, and whether to use these products in male daily life really are the questions.

ISSN 1008-682X EISSN 1745-7262 CN 31-1795/R

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