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Moira Kathleen O' Bryan |
Associate Professor
Senior Research Fellow & Senior Scientist, Centre for Reproduction & Development, Monash Institute of Medical Research, Australia.
Tel: +61 3 9594 7125 Fax: +61 3 9594 7111
Email: moira.obryan@med.monash.edu.au |
Assoc Prof Moira O'Bryan?s research focuses on the identification of key regulatory processes in sperm development and function. Assoc Prof O?Bryan received her PhD from The University of Melbourne, Department of Medicine (St. Vincent?s Hospital) in 1994 in the area of complement regulation and its relevance to human male fertility. She then moved to The Population Council, Center for Biomedical Research in New York as an Andrew Mellon Foundation Post-doctoral Fellow where she worked on the purification and characterization of Sertoli cell derived regulators of pituitary function. In 1996, Assoc Prof O?Bryan returned to Australia to take up a position at MIMR as an NHMRC Peter Doherty Fellow.
Assoc Prof O?Bryan has published extensively in the areas of the interaction between the immune system and male fertility, endocrine regulation, the identification and characterization of novel sperm tail proteins and the genetics of male infertility.
Assoc Prof O?Bryan is a Chief Investigator on an Australian Research Council Centre of Excellence in Biotechnology and Development. She also holds several NHMRC grants. She is involved in the running of the Monash Male Infertility Repository, which is a valuable resource of clinical material and data on men with male infertility. She is currently the management group chair of the Australian Phenomics Network.
Assoc Prof O?Bryan has received awards from the Australian Academy of Science, the Fertility Society of Australia, the Endocrine Society of Australia, and the Society for Reproduction (Australia). Recently Dr O'Bryan was named as The American Society of Andrology "2008 Young Andrologist of the Year". She has been involved in the promotion medical research as a national director of the Australian Society for Medical Research and as an advisor to Andrology Australia.
Employment & Education
2001 - present:
2000 (Aug) - 2001:
2000 (Jan.) - 2000 (Aug):
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NH&MRC R.D. Wright Fellow and Senior Scientist, Monash Institute of Reproduction and Development (MIRD), Monash University, 27-31 Wright St., Clayton 3168.
Senior Scientist and NH&MRC Senior Research Officer, Monash Institute of Reproduction and Development (MIRD), Monash University, 27-31 Wright St., Clayton 3168.
NH&MRC Senior Research Officer, Monash Institute of Reproduction and Development (MIRD), Monash University, 27-31 Wright St., Clayton 3168.
Peter Doherty Postdoctoral Fellowship (NH&MRC #967135), Monash Institute of Reproduction and Development (IRD), 27-31 Wright St., Clayton 3168. Australia.
Post-doctoral Research Fellow, The Population Council, Center for Biomedical Research, 1230 York Ave., New York, N.Y. 10021. U.S.A.
Ph.D. (Medicine), The University of Melbourne, awarded April 1994. Supervisors: Drs. B.F. Murphy1 and H.W.G. Baker2. 1The Department of Nephology, St Vincent?s Hospital, Victoria Pde., Fitzroy, 3065 and 2The Department of Obstetrics and Gynaecology, The Royal Women?s Hospital, Grattan St., Carlton, 3053. Australia. Dissertation title: Clusterin in the male reproductive tract and in cell death - awarded April 1994.
Bachelor of Science with first class honours - pathology, The University of Melbourne, Parkville, 3052. Australia.
1985-1987: Bachelor of Science, The University of Melbourne, Parkville, 3052. Australia. |
Awards and Distinctions
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Best Project award from The Rebecca Cooper Medical Research Foundation. Co-held with Gerard Gibbs (post-doc in my group).
Monash University Research Fund Travel Award
NHMRC R.D. Wright Career Development Award.
Monash University Research Fund Travel Award
Australian Academy of Science, Career Development Award, Presented at the Australian Academy of Science ? Science at the Shine Dome Symposium, May 2001.
European Society for Reproduction and Endocrinology ? Fertility Society of Australian Young Scientist lecture, Tour, France, July.
Best Presentation by a Young Scientist, The Fertility Society of Australia. Presented at the annual meeting in Hobart, October.
Serono Post-graduate Travel Award, Endocrine Society of Australia.
Junior Scientist Nomination, Australian Society for Reproductive Biology - unable to compete due to family illness.
NHMRC Peter Doherty Post-doctoral Fellowship.
ARC Australian Post-doctoral Fellowship ? never activated due to concurrent NHMRC Fellowship.
Mellon Foundation Post-doctoral Fellowship to work at The Population Council Centre for Biomedical Research, Rockefeller University, New York.
Ph.D. (Medicine), The University of Melbourne. Australia.
Australian Post-graduate Research Award, The Commonwealth Government of Australia.
Bachelor of Science with first class honours. The University of Melbourne. Australia.
Donovan Faculty Scholarship - Newman College, The University of Melbourne. |
Grants and research contracts
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Andrology Australia (The Australian Centre of Excellence in Male Reproductive Health). National DNA repository for the identification of genetic causes of male infertility. CIs: Moira O?Bryan and Rob McLachlan. $75,000 per annum.
NHMRC Program Grant. CIs: David de Kretser, Gail Risbridger, Milton Hearn, Graham Jenkin, Mark Hedger, Euan Wallace, Kate Loveland, David Phillips, Moira O?Bryan. ~$1.56M/year.
NHMRC Enabling Grant. The Australian Phenome Bank. Chief investigators: Chris Goodnow, David de Kretser, Moira O'Bryan. $300K per year for 5 years.
NHMRC Large Equipment Grant for a gel documentation system. CIs: Loveland, Moran, O?Bryan et al $61,200.
Rebecca Cooper Medical Research Foundation. Identificaton of genes essential for male fertility ? equipment grant. CIs: Gerard Gibbs, Moira O?Bryan. $15,000. Prize for highest ranking application.
Schering AG research contract to identify novel contraceptive targets and mechanisms and regulators of prostate disease. CIs: David de Kretser, Evan Simpson, Gail Risbridger, Rob McLachlan, Moira O'Bryan, Lisa O?Donnell. ?600,000 per year.
NHMRC Large Equipment Grant for a denaturing high performance liquid chromatography system. CIs: Moira O?Bryan, David de Kretser, David Cram, Rob McLachlan, Colin Clyne, Ed Stanley, Peter Fuller, Andrew Elefanty, Vincent Harley, Evan Simpson and Andrew Perkins. $71,000.
The Australian Research Council, Centre for Excellence. $9,458,900. Biotechnology and Development. CIs: John Aitken (Director), David de Kretser, Gary Hime, Michael Holland, David Jans, Peter Koopman, Kate Loveland, Eileen McLaughlin, Moira O?Bryan, Andrew Sinclair, Sean Roman.
Monash University. $20,000. A proteomic analysis of the rat sperm tail. CI: Moira O?Bryan, Co-investigator: Gerard Gibbs.
Monash IVF. The Genetics of Male infertility. $48,000. CIs Moira O'Bryan, David Cram, David de Kretser and Rob McLachlan.
Andrology Australia (The Australian Centre of Excellence in Male Reproductive Health). National DNA repository for the identification of genetic causes of male infertility. CI: Moira O?Bryan. Co-investigator: David de Kretser. $267,602.
NHMRC Equipment Grant for a high performance liquid chromatography system. CIs: Drs David de Kretser, David Phillips, Mark Hedger, Kate Loveland, Moira O?Bryan, John Morrison, Gail Risbridger, Martin Pera, Paul Hertzog. $86,000.
NHMRC program grant Reproductive Processes. CIs: Drs. David de Kretser, Milton Hearn, Mark Hedger, Graham Jenkin, Kate Loveland, John Morrison, Moira O?Bryan, David Phillips and Gail Risbridger. $1.7M / year.
Rebecca Cooper Medical Research Foundation. The genetics of male infertility - gene discovery and mutation detection. $10,000.
Monash IVF Research Grant, Monash IVF, Victoria CIs David Cram, Moira O'Bryan, David de Kretser and Rob McLachlan $28,000. |
Community Service, Committees
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Deputy convener. ASMR National Scientific Conference. Couran Cove, QLD. November, 2005.
Program organizing committee. Inaugural mammalian phenomics workshop, November 18-20, 2004, The Australian National University, Canberra.
National Director, The Australian Society of Medical Research.
Convener, The Victorian branch of the Australian Society for Medical Research Medical Research Week, 2003.
Convener, The Victorian branch of the Australian Society for Medical Research Medical Research Week, 2003.
Organization committee, Australian Health and Medical Research Congress 2002 (AHMRC 2002) 25-29 November 2002 in Melbourne.
Post-graduate course work degrees committee, Monash University.
Secretary, The Victorian branch of The Australian Society for Medical Research.
Convener, The Prince Henry?s Institute of Medical Research and Monash Institute of Reproduction and Development joint symposium on Reproductive Genomics, December 5-6, 2001. Monash Medical Centre, Clayton 3168.
The subject of a documentary made by The Australian Academy of Science. This documentary consisted of a half hour interview about my life and science towards the purpose of attracting secondary school students to continue science at University. The project was funded by the ARC and videos will eventually be distributed to every secondary school in Australia.
Committee member, The Victorian branch of The Australian Society for Medical Research.
Post-graduate students committee - Monash Institute of Reproduction and Development.
Mentor, Masters of Reproductive Biology Masters Programme, Monash University.
Mentor, Department of Neurosciences, Monash University.
Deputy Radiation Safety Office, Monash Institute of Reproduction and Development.
Senior honours year examiner, Department of Anatomy, Monash University.
Radiation Safety Officer, Monash Institute of Reproduction and Development. |
Editorial Boards
2004-present: The Biology of Reproduction (Official journal of the American Society for the Study of Reproduction).
Executive positions
2004-present: The access and advisory committee, The Australian Phenome Bank, The Australian Phenomics Facility, Canberra.
2003-present: National Director, The Australian Society of Medical Research.
2001-present: Male infertility advisory group, Andrology Australia (The Centre for Excellence in Men?s Reproductive Health).
University appointments
2004: Assessment Panel for the Strategic Grant Scheme, Monash University
2001: Monash University Post-graduate students course work committee
Teaching
2004-presents: BMS3011 male reproductive biology lectures.
1997-present: Guest lecturer, 3rd year anatomy, Department of Anatomy, Monash University.
BSc honours students: 8
Society Membership
The Endocrine Society of Australia
The Australian Society of Medical Research
The Australian Society for Reproductive Biology
Andrology Society of America
Invited speaker
1997: Hormones and Men?s Health. Prince Henry?s Institute of Medical Research in conjunction with the Institute of Reproduction and Development, Monash University. Sperm tail proteins and motility. Melbourne, Australia, February 1997.
1998: The Australian Society for Medical Research. The Emerging Genetic Basis for Male Infertility - Sperm tail proteins and motility. Hobart, Australia, November 1998.
1999: 15th Annual Meeting of the European Society of Human Reproduction and Embryology FSA/ESHRE exchange lecture - Tpx-1 in the testis and sperm function. Tours, France, June 1999.
2000: Department of Anatomy and Cell Biology, Queen?s University, Kingston, Ontario, Canada, July.
2001: Secondary Teachers Association of Victoria annual conference. Glen Waverly Secondary College. June.
2003: Department of Anatomy and Cell Biology, The University of Melbourne. The outer dense fibres of the sperm tail. Function and fertility. October.
2004: School of Biological Sciences, Monash University. Mouse and human approaches to a greater understanding of male fertility, May.
2004: Major National Research Facilities Road Show. Walter and Elisa Hall Institute, Parkville, October. "How to crack the nut of male infertility"
2004: Prince Henry?s Institute of Medical Research. "Of snakes and sperm: CRISP proteins" December.
2005: The Inaugural Mammalian Phenomics Symposium, The Australian National University, Canberra. February.
Publications (.doc)
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