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P Ganesan Adaikan
SUMMARY
Dr. P Ganesan Adaikan, PhD, DSc, ABS (USA) is a Professor and Head, Section of Sexual Medicine and is a Board Certified (USA) Clinical Sexologist in the Department of Obstetrics & Gynaecology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore, 5, Lower Kent Ridge Road, Singapore 119074. Email: p_ganesan_adaikan@nuhs.edu.sg
He is a world renowned expert in the field of sexual medicine and is recognized for his pioneering contributions to the physiopharmacology of penile erection and pharmacological treatment for erectile dysfunction. He has won several international awards including the prestigious Ginestie Prize (1986) in Prague and Emil Tanagho Prize (2006) in Cairo from the International Society for Sexual Medicine (ISSM), American Medical Systems–Excellence in Impotence Research Best Paper Award (1997) from the Asia-Pacific Society for Sexual Medicine (APSSM) and the Benjamin Henry Sheares Memorial Lecture Award and Gold Medal (1987) from the Obstetrical and Gynaecological Society of Singapore.
He was the first in the world to identify the neurogenic non-adrenergic, non-cholinergic pathway and the modulator/transmitter nitric oxide and several other receptors/mediators in the human penis. This initial discovery was a major impetus to worldwide pharmacological research among the fraternity in this area and eventual development of drugs such as Viagra, Cialis and Levitra. He also pioneered the identification of the mechanism of erection and intracavernous use of PGE1 for the treatment of erectile dysfunction (covered by 11 publications and 220 citations from these articles) and thereafter, a series of pathophysiological elucidations of impotence and in recent time, identification of gaseous hydrogen sulphide as the modulator and co-transmitter for penile erection. His current focus of research is on stem cell, hydrogen sulphide therapy, pathophysiology of chloride channels and aspects of female sexual dysfunctions.
He holds a recently approved Singapore and US patent (09/714,614) for the discovery of pro-endogenous pharmacotherapy for the treatment of Priapism through National University of Singapore.
Teachings:
He has been a lecturer to MBBS, MMed, Pharmacy and Advanced nursing courses and is a teacher and research supervisor in the field of sexual medicine to several PhD, MD, MSc and clinical MSc students at the National University of Singapore and other universities and examiner for post-graduate students in these areas.
Publications:
Dr Adaikan has published more than 180 scientific articles in leading peer-reviewed international journals. He has delivered more than 600 invited lectures and presentations around the world in the area of sexual medicine.
Clinical Services:
With his relentless scientific pursuit in the area of erectile dysfunction, Prof Adaikan established the Male and Female Sexual Dysfunction section in the Andrology clinic of the department at the National University Hospital in 1986 - which is fully functional to-date.
Professional Societies:
Prof Adaikan was the first Asian President and now the Past President of the International Society for Sexual Medicine. He is also in the Nomination Committee of ISSM and in the International Advisory Board of the Journal of Sexual Medicine and 5 other international journals. Prof Adaikan is the Past President of Asia-Oceania Federation for Sexology and current President of Society for the Study of Andrology and Sexology, Singapore (SSASS) which he founded in 1997. He is also the Founder-Executive Committee member of the Asia Pacific Society for Sexual Medicine (1987). In addition, his current positions include: Honorary President, Asia Pacific Society for Sexual Medicine, President and Associate Secretary and Advisory Committee Member of World Association for Sexual Health (WAS).
Courses/Congresses conducted:
Since 1993, he has organised (2-days) annual CME training courses for doctors in Singapore and the Asian region on male and female sexual dysfunction (13 workshop/symposia to date).
Prof Adaikan was the organizing Chairman/President of the 6th World Meeting on Impotence (1994), 7th Asian Congress of Sexology (2002) and the 12th Biennial Meeting of APSSM (2009) held in Singapore. As the President of ISSM (2004-2006), he was the co-chair of the 12th World Congress of Sexual Medicine held in Cairo, Egypt in September 2006. He was also the ISSM’s Scientific Chair and Co-Chair respectively for the 13th Joint World Meeting of ISSM and ESSM in Brussels (2008) and 3rd International Consultation in Sexual Medicine in Paris (2009).
Consultancy:
Over the years, Dr Adaikan has been a consultant, thought leader and resource speaker on drugs for several pharmaceutical industries in the areas of cardiovascular, respiratory and sexual medicine at the international level.
SOME DETAILS
INTERNATIONAL / CONTINENTAL AWARDS
Moynihan Prize and Medal, British Surgical Society (1973), for use of prostaglandins for gastric and duodenal ulcer French Government Exchange Fellowship invitation (1985) for collaborative research and training at the Centre for Study and Research on Impotence, Paris, France Prestigious Ginestie Prize and Diploma (1986) for the best research contribution in the world by the International Society for Impotence Research (Adjudged by International juries as the best out of contributions from 11 reputed International Research centers) at the 2nd World Meeting on Impotence in Prague, Czechoslovakia (first competitive prize by ISSM-1986) Benjamin Henry Sheares Memorial Lecture Award and Gold Medal (1987) by the Singapore Society of Obstetrics and Gynaecology, Singapore First ‘Recognition Award’ (1994) by the Asian Oceania Federation of Sexology for “unparalleled contribution in the field of basic and clinical research in erectile dysfunction”, New Delhi, India American Medical Systems (AMS) – Excellence in Impotence Research Best Paper Award (1997) at the VI Asia Pacific Meeting on Impotence at Kuala Lumpur, Malaysia (an award open to International participants once in two years) Outstanding ‘Indian-Outside India Award’ (2004) bestowed by the Executive Committee of the First Asia Pacific Conference of Sexology, in Mumbai, India Emil Tanagho Prize for Best Innovative Research in Sexual Medicine (2006) awarded by the International Society for Sexual Medicine at the 12th World Meeting on Sexual Medicine in Cairo, Egypt Life Time Excellence Award (2010) Presented during the 5th International Conference on Sexology (13-14 Jan 2010, Chennai, India) in appreciation of the “dedicated contributions and efforts in the field of sexual medicine and the example set for the medical community”
CHAIRMAN OF THE JUDGING COMMITTEES FOR PRESTIGIOUS INTERNATIONAL AWARDS / PRIZES FOR SEXUAL DYSFUNCTIONS
Chairman, Judging Committee for the Female Sexual Dysfunction Award at the XI World Meeting on Impotence, Buenos Aires, Argentina (2004) Chairman, Judging Committee for the Best Innovative Research (Tanagho) Award at the VIII World Meeting on Impotence, Amsterdam, The Netherlands (1998) Chairman, Judging Committee for the Best Paper Award at the VI Biennial Asia-Pacific Meeting on Impotence, Kuala Lumpur, Malaysia (1997) Chairman, Judging Committee for the Ginestie Award at the VII World Meeting on Impotence, San Francisco, USA (1996) Member, Judging Committee for the Ginestie Award at the III World Meeting on Impotence, Boston, USA (1988)
PROFESSIONAL COMMITTEES / SOCIETIES / MEMBERSHIP
International Society for Sexual Medicine (ISSM): President-Elect (2002-2004); President (2004-2006); Past-President (2006-2008). He was also the Board member and Chairman of Scientific committee, ISSM. He is the first Asian to be elected to the prestigious post of President of this society. Asia-Oceania Federation for Sexology - First Vice-President (94-96), President-Elect (1996-2002), President (2002-2004) and Past-President (2004-). Responsibility includes coordinating all Asia-Pacific countries in issues of sexual health through respective executive committee members. Asia-Pacific Society for Sexual Medicine (APSSM) – Honorary President (2009-) and Founder, Executive Committee (1987-) Society for the Study of Andrology and Sexology, Singapore (SSASS): He is the founder of this society. His positions include Past-President (2003-2005), President (1999-2003; 2009-) and Vice-President (1997-1999). He affiliated this society with the International Society of Andrology and World Association for Sexology. Through this society, he has been continuously involved in creating awareness in sexual medicine through a variety of activities for professionals as well as general public; this includes publication of the official newsletter (SSASS Press) and periodic public forums conducted on current issues in this area. World Association for Sexual Health (WAS) – Associate Secretary and Advisory Committee Member and Member of the Scientific Committee (2009-). He has also been a member of the International Scientific Committee of its World Congresses since 1987-. International Advisory / Scientific Committees to several Asian and World Congresses. His responsibilities include expert advice on scientific programme, vetting abstract submissions for major international congresses. Registered member, American Board of Sexology Member, Obstetrical and gynaecological society of Singapore Member, International Society for the Study of the Aging Male Member, Sexual Medicine Society of North America Fellow, Institute of Biology, UK (1987-) Executive committee member (1987) and member, Singapore Planned Parenthood Association
EDITORIAL BOARD (peer-reviewed journals)
Journal of Sexual Medicine - since the inauguration in 2004 (USA) Journal of the British Association for Sexual and Relationship Therapy, since 2002 (UK) Asia Pacific Journal of Pharmacology - since the inauguration in 1985 (Singapore) Asian Journal of Andrology - since the inauguration in 1999 (China) Current Sexual Health Reports - since the inauguration in 2004 (USA) Sexual Health – since the inauguration in 2004 (Australia)
OTHER INTERNATIONAL RECOGNITION
Selected and included in the original Marquis WHO’S WHO in the World: Illinois, USA, (1989) and in the first edition of WHO’S WHO in Science and Engineering, USA (1992) Included in the International Directory of Distinguished Leadership (1990) and selected as Professional of the Year in Science and Research by American Biographical Institute, North Carolina, USA
SERVICE TO PROFESSION/INDUSTRY
Global advisory board member and Consultant, Eli Lilly International, Indianapolis, USA Advisory Consultancy, Boehringer-Ingelheim, Johnson and Johnson and Pfizer, USA
He participated by invitation in the Second and Third International Consultation on Erectile and Sexual Dysfunction (WHO sponsored) – 2003 and 2009, Paris, France. He was one of the international experts in preparing the ISSM Definition for Premature Ejaculation (2008) and Co-Editor of the Guidelines Book, 3rd International Consultation on Sexual Medicine, Paris, Health Publication Ltd, 2010.
RESEARCH PUBLICATIONS
Published papers: 180 Conference papers presented and published: 600
(Over 250 invited State of the Art, Plenary and Symposium lectures around the world) Chapters in Books: 26; Invited Editorial Comments: 2
OVER THE YEARS, HIS INTENSIVE RESEARCH IN THE FIELD OF SEXUAL MEDICINE HAS LED TO THE FOLLOWING DISCOVERIES
Discovery of non-adrenergic, non-cholinergic neurotransmission and various receptors (1978), establishment of hypothesis on the autonomic control of penile erection and identification of nitric oxide as the neurotransmitter of erection and mediator of cGMP pathway in the human penis (1991) Pioneer identification of the mechanism of action in the corpus cavernosum and clinical use of PGE1 for the treatment of erectile dysfunction. This has been an important drug in the management of impotence (by intracavernous and intraurethral routes) around the world. In recent time, identification of the modulatory role of Hydrogen Sulphide as co-transmitter of penile erection. He holds a recently approved Singapore and US patent (09/714,614) for the discovery of pro-endogenous pharmacotherapy for the treatment of Priapism through National University of Singapore.
RESEARCH GRANTS
He has been awarded more than 12 scientific research grants amounting to about S$2.5 million over the years that include local/international industrial invitation for drug testing / clinical trials and research on male and female sexual dysfunction.
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