| |
Toshiaki Noce |
Professor
Mitsubishi Kagaku Institute of Life Sciences (MITILS) Minamiooya 11, Machida-shi, Tokyo 194-8511, Japan.
Tel: +81-042-724-6246 Fax: +81- 042-724-6314
Email: noce@libra.ls.m-kagaku.co.jp |
Education
1974-1979: Faculty of Science, Kyoto University, Kyoto, Japan, B. Sc. degree (Major in Biology, 1979)
1979-1981: Faculty of Science, Kyoto University, Kyoto, Japan, M.D. degree (Major in Developmental Biology, 1981)
Supervisor: Prof. Ikuo Takeuchi
1981-1984: Faculty of Science, Kyoto University, Kyoto, Japan, Ph.D. degree (Major in Developmental Biology, 1984)
Thesis Supervisor: Prof. Ikuo Takeuchi
Career
1985-1986: Post-doctoral Fellow, Department of Biology, McGill University, Montreal, Canada, Supervisor: Dr. Adrian Tsang
1986-1987: Post-doctoral Fellow, (granted by fund for Promoting Science and Technonogy, Japan) Department of Developmental
Biology, National Institute of Basic Biology, Okazaki, Japan. Supervisor: Prof. Ikuo Takeuchi
1987-1989: Researcher, Department of Developmental Biology, Mitsubishi Kasei Institute of Life Sciences
1989-present: Senior Researcher, Mitsubishi Kasei Institute of Life Sciences
Present: Mitsubishi Kagaku Institute of Life Sciences, Project Leader of Regenerative and Developmental Biology, Group Leader of Pluripotency and Initialization
Current Interests
Using mouse vasa (Mvh) gene expression as a visualizing marker for germ cell differentiation, we have first succeeded in developing a culture system for producing germ cells from ES cells (PNAS, 100, 11457-11462, 2003). Specific interest is currently focused on understanding the molecular mechanism regulating the germ / somatic cell segregation and the maintenance of totipotency in germ cell lineage. Furthermore, as an attempt to understand the totipotency, we are trying to investigate the reprogramming event that is occurred in the process of nuclear transfer of somatic nuclei into egg cytoplasm.
Publications (.doc)
|
