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She-Pu Xue |
Professor, Academician of the Chinese Academy of Sciences
Department of Cell Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, 100005 Beijing, China.
Email: spxue@public.bta.net.cn |
Professor Xue Shepu, male, born in 1917, academician of the Chinese Academy of Sciences. He graduated from Chongqing Central University in 1943, received his masters from the same university in 1947, and received his doctorate from Washington University, St. Louis in 1951. Xue Shepu provided a theoretical basis for cell differentiation roles and its control while contributing to research concerning Chinese male reproductive biology and birth control that absorbed gossypol. He established a cybrid model i.e. cytoplasmt of red blood cell fused with marrow tumor cells. He discovered that several factors was related to denucleation, and was the first to discover that EDDF existed in mammalian red blood cells which could reverse malignantcy of cancer cells. Xue?s purified active matter had a highly active growth inhibition effect on tumor cells and proposed a nucleus concentration and denucleation theory and new concepts of cancer treatment.
Publications
Quanhong Ma, Haikun Wang, Rui Guo, Huizhen Wang, Yehua Ge, Jing Ma, Shepu Xue, Daishu Han. Molecular cloning and characterization of SRG-L, a novel mouse gene developmentally expressed in spermatogenic cells. Mol Reprod Dev. 2006 Sep;73(9):1075-83.
Pengpeng Ma, Huizhen Wang, Rui Guo, Quanhong Ma, Zuoren Yu, Yi Jiang, Yehua Ge, Jing Ma, Shepu Xue, Daishu Han Stage-dependent Dishevelled-1 expression during mouse spermatogenesis suggests a role in regulating spermatid morphological changes. Mol Reprod Dev. 2006 Jun;73(6):774-83.
Huizhen Wang, Yongmei Chen, Yehua Ge, Pengpeng Ma, Quanhong Ma, Jing Ma, Haikun Wang, Shepu Xue and Daishu Han. Immunoexpression of Tyro 3 Family Receptors?Tyro 3, Axl, and Mer?and Their Ligand Gas6 in Postnatal Developing Mouse Testis. J Histochem Cytochem. 2005 Nov;53(11):1355-64.
Rui GUO, Peng-Peng MA, Jing MA, Ye-Hua GE, She-Pu XUE, and Dai-Shu HAN. Cloning and Characterization of a Novel Gene SRG-L Expressed in Late Stages of Mouse Spermatogenic Cells. ABBS 2004, 36:315-322.
Pengpeng Ma, Yehua Ge, Shali Wang, Jing Ma, Shepu Xue and Daishu Han. Spermatogenesis following syngeneic testicular transplantation in Balb/c mice. Reproduction 2004, 128:167-170.
Guo Rui, Zuoren, Yu, Jikui Guan, Yehua Ge, Jing Ma, Sai Li, Shali Wang, Shepu Xue, and Daishu Han. Stage-specific and tissue-specific expression characteristics of differentially expressed genes mouse spermatogenesis. Molecular Reproduction and Development 2004, 67(3):264-272.
Zuoren Yu , Rui Guo, Yehua Ge, Jing Ma, Jikui Guan, Sai Li, Xiaodong Sun, Shepu Xue, and Daishu Han. Gene Expression Profiles in Different Stages of Mouse Spermatogenic Cells During Spermatogenesis. Biology of Reproduction 2003, 69(1):37-47.

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