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《亚洲男性学杂志》 2012; 14 (3): 393–399

前列腺癌中ETS重排

Mark A Rubin (美国)

前列腺癌是一种临床分子异质性疾病。了解前列腺癌的生物学基础有助于更好地理解生物学与疾病发生风险的关联及其新的治疗方法的开发。该综述主要探讨近年来发现的前列腺癌中普遍存在的ETS和非ETS基因重排相关研究。前列腺癌基因融合的基础研究将有助于我们对临床生物学多样性的理解，从而为该疾病从原理上提供分子亚分类。

关键词：基因融合，下一代测序，前列腺癌，TMPRSS2:ERG，转座

此摘要文献来源：
Mark A Rubin. ETS rearrangements in prostate cancer. Asian J Androl 2012; 14: 393–399.