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Asian Journal of Andrology (2012) 14, 784–787; doi:10.1038/aja.2012.41; published online 16 July 2012
Comparison between primary angioplasty and thrombolytic therapy on erectile dysfunction after acute ST elevation myocardial infarction
Ramazan Akdemir1, Özlem Karakurt2, Salih Orcan5, Nihat Karakoyunlu3, Mustafa Mucahit Balci4, Levent Sağnak3, Hamit Ersoy3, Mehmet Bulent Vatan1, Harun Kilic5 and Ekrem Yeter5
1 Department of Cardiology, Faculty of Medicine, Sakarya University, Sakarya 54054, Turkey
2 Department of Cardiology, Balikesir Government Hospital, Balikesir 10100, Turkey
3 Department of Urology, Dışkapı Yıldırım Beyazıt Research and Education Hospital, Ankara 06110, Turkey
4 Department of Cardiology, Yuksek Ihtisas Research and Education, Ankara 06590, Turkey
5 Department of Cardiology, Dışkapı Yıldırım Beyazıt Research and Education Hospital, Ankara 06110, Turkey
Correspondence: Dr R Akdemir, (rakdemir@yahoo.com)
Received 3 January 2012; Revised 7 February 2012; Accepted 2 April 2012
Advance online publication 16 July 2012.
| Abstract |
Acute ST elevation myocardial infarction has high mortality and morbidity rates. The majority of patients with this condition face erectile dysfunction in addition to other health problems. In this study, we aimed to investigate the effects of two different reperfusion strategies, primary angioplasty and thrombolytic therapy, on the prevalence of erectile dysfunction after acute myocardial infarction. Of the 71 patients matching the selection criteria, 45 were treated with primary coronary angioplasty with stenting, and 26 were treated with thrombolytic agents. Erectile function was evaluated using the International Index of Erectile Function in the hospital to characterize each patient's sexual function before the acute myocardial infarction and 6 months after the event. The time required to restore blood flow to the artery affected by the infarct was found to be associated with the occurrence of erectile dysfunction after acute myocardial infarction. The increase in the prevalence of erectile dysfunction after acute myocardial infarction was 44.4% in the angioplasty group and 76.9% in the thrombolytic therapy group (P=0.008). In conclusion, this study has shown that reducing the time of reperfusion decreases the erectile dysfunction prevalence, and primary angioplasty is superior to thrombolytic therapy for decreasing the prevalence of erectile dysfunction after acute myocardial infarction.
Keywords: coronary angioplasty; erectile dysfunction; fibrinolysis; myocardial infarction; myocardial reperfusion |
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