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Abstract

Volume 13, Issue 3 (May 2011) 13, 494–498; 10.1038/aja.2010.110

Single-centre study comparing standard apical dissection with a modified technique to facilitate vesico-urethral anastomosis during laparoscopic radical prostatectomy

Xin Gao*, Xiao-Yong Pu*, Jie Si-Tu and Wen-Tao Huang

Department of Urology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China

* These authors contributed equally to this work.

Correspondence: Dr X Gao, (gaoxin44@vip.163.com)

Received 28 April 2010; Revised 12 June 2010; Accepted 8 July 2010; Published online 7 February 2011.

Abstract

A modified apical dissection of the prostate to improve the efficiency of vesico-urethral anastomosis (VUA) in laparoscopic radical prostatectomy (LRP) was reported. A total of 42 patients were randomly selected and enrolled in this study. A standard LRP was performed in 21 patients (group 1), whereas a novel, modified apical dissection of the prostate in LRP was performed in another 21 patients (group 2). Surgical data, total operative time, VUA time, extravasation rate, catheterisation time, occurrence of anastomotic strictures, and the early and late continence rates were analysed statistically. No differences in clinical or pathological characteristics were determined between the two groups. The total operative time, VUA time, blood loss and catheterisation time were lower in group 2, which received the novel, modified technique compared with group 1, which received the standard technique to dissect the apex of the prostate (P<0.01 for each variable). Regarding the extravasation rate and the occurrence of anastomotic strictures, no significant differences were found between the two groups (P>0.05 for each). After catheter removal, a statistically significant difference in the continence rates was present at 3 and 30 days post operation in the two groups (P<0.01, respectively). At 90 days post operation, the difference, although still present, was no longer statistically significant (P>0.05). The novel, modified apical dissection of the prostate facilitates the VUA and significantly improves the efficacy of the procedure and early restoration of continence.

Keywords: continence; laparoscopic technique; radical prostatectomy; vesico-urethral anastomosis

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Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.