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Volume 15, Issue 6 (November 2013) 15, 713–714; 10.1038/aja.2013.113
Autonomic nerve development contributes to prostate cancer progression
John Bauman and Kevin McVary
Division of Urology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA
Correspondence: Dr K McVary, (kmcvary@siumed.edu)
30 September 2013
| Abstract |
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In a significant translational study, Magnon et al. investigated the role that the autonomic nervous system plays in the development and spread of prostate cancer in both mice and human models. The study shows different roles for both branches of the autonomic nervous system, with the sympathetic system promoting early stages of tumorigenesis, and the parasympathetic system promoting cancer dissemination. This information could lead to important new foundations for treatment, therapies and management of prostate cancer.
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