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Abstract

Volume 11, Issue 2 (March 2009) 11, 209–214; 10.1038/aja.2008.1

Evaluation of erectile function after urethral reconstruction: a prospective study

Hong Xie, Yue-Min Xu, Xiao-Lin Xu, Yin-Long Sa, Deng-Long Wu and Xin-Chi Zhang

Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China

Correspondence: Dr Yue-Min Xu, Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, No. 600 Yi Shan Road, Shanghai 200233, China. Fax: +86-21-64083783 E-mail: xuyuemin@263.net

Received 14 March 2008; Revised 2 June 2008; Accepted 4 August 2008; Published online 5 January 2009

Abstract

We conducted a prospective study of erectile dysfunction (ED) after urethral reconstructive surgery, using the 5-item International Index of Erectile Function (IIEF-5), the Sexual Life Quality Questionnaire (SLQQ) and the Quality of Life Questionnaire (QoLQ). Between January 2003 and July 2007, 125 male patients with urethral strictures underwent urethroplasty, and pre- and post-surgery erectile function was assessed using these three questionnaires. A formula to predict the probability of ED after urethroplasty was derived. At 3 months post-operatively, there was a significant decrease in IIEF-5 (16.57 ±7.98) and SLQQ scores (28.71±14.84) compared with pre-operative scores (P < 0.05). However, the IIEF-5 scores rebounded at 6 months post-operatively (17.22±8.41). Logistical regression analysis showed that the location of the urethral stricture, the recurrence of strictures and the choice of surgical technique were predictive of the post-operative occurrence of ED. This study identified the clinical risk factors for ED after urethroplasty. Posterior urethral stricture and end-to-end anastomosis were found to have a strong relationship with erectile function. The logistical model derived in this study may be applied to clinical decision algorithms for patients with urethral strictures.

Keywords: erectile dysfunction, urethroplasty, urethral stricture

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Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.