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Volume 12, Issue 3 (May 2010) 12, 376–380; 10.1038/aja.2010.7

Eurycoma longifolia Jack in managing idiopathic male infertility

Mohd Ismai

1 Wellmen Clinic, Damai Service Hospital, Kuala Lumpur 52100, Malaysia
2 Department of Community Medicine, School of Medical Sciences, University Sains Malaysia, Kbg Kerian, Kelantan 16150, Malaysia

Correspondence: Dr Mohd Ismail Bin Mohd Tambi, dr_tambi@yahoo.com

Received 27 September 2009; Revised 23 November 2009; Accepted 21 January 2010; Published online 29 March 2010.


This study investigated the effect of treatment with the proprietary standardized, water-soluble extract of the root of the Malaysian plant, Eurycoma longifolia Jack, which is thought to enhance male fertility with regard to higher semen volumes, sperm concentrations, the percentage of normal sperm morphology and sperm motility in male partners of sub-fertile couples with idiopathic infertility. A total of 350 patients were given 200 mg of the extract daily and follow-up semen analyses were performed every 3 months for 9 months. Of these 350 patients, 75 patients completed one full cycle of 3 months. Follow-up semen analyses in these patients showed significant improvement in all semen parameters. The proprietary extract of Eurycoma longifolia Jack significantly improved the sperm quality in these patients, allowing for 11 (14.7%) spontaneous pregnancies.

Keywords: male infertility; medicinal herbs; semen

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Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.