Home  |  Archive  |  Online Submission  |  News & Events  |  Subscribe  |  APFA  |  Society  |  Links  |  Contact Us  |  中文版
Search   
 
Journal

Ahead of print
Authors' Accepted
    Manuscripts
new!
Current Issue
Archive
Acknowledgments
Special Issues
Browse by Category

Manuscript Submission

Online Submission
Online Review
Instruction for Authors
Instruction for Reviewers
English Corner new!

About AJA

About AJA
Editorial Board
Contact Us
News

Resources & Services

Advertisement
Subscription
Email alert
Proceedings
Reprints

Download area

Copyright licence
EndNote style file
Manuscript word template
Guidance for AJA figures
    preparation (in English)

Guidance for AJA figures
    preparation (in Chinese)

Proof-reading for the
    authors

AJA Club (in English)
AJA Club (in Chinese)

Links

Meetings
Journals
Societies & Institutes
Hospitals
Databases & Libraries
Companies
Websites
Other links

 
Abstract

Volume 14, Issue 1 (January 2012) 14, 156–163; 10.1038/aja.2011.114

Medical management of ischemic stuttering priapism: a contemporary review of the literature

Helen R Levey1, Omer Kutlu2 and Trinity J Bivalacqua2

1 The Arthur Smith Institute for Urology, North Shore - Long Island Jewish Health System, New Hyde Park, NY 11010, USA
2 The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins Hospital, Baltimore, MD 21287, USA

Correspondence: Dr HR Levey, (Helen.Levey@gmail.com)

Received 22 April 2011; Revised 10 June 2011; Accepted 15 June 2011; Published online 7 November 2011

Abstract

Priapism is defined as a prolonged and persistent erection of the penis without sexual stimulation. This is a poorly understood disease process with little information on the pathophysiology of this erectile disorder. Complications from this disorder are devastating due to the irreversible erectile damage and resultant erectile dysfunction (ED). Stuttering priapism, though relatively rare, affects a high prevalence of men with sickle-cell disease (SCD) and presents a challenging problem with guidelines for treatment lacking or resulting in permanent ED. The mechanisms involved in the development of priapism in this cohort are poorly characterized; therefore, medical management of priapism represents a therapeutic challenge to urologists. Additional research is warranted, so we can effectively target treatments for these patients with prevention as the goal. This review gives an introduction to stuttering priapism and its clinical significance, specifically with regards to the patient with SCD. Additionally, the proposed mechanisms behind its pathophysiology and a summary of the current and future targets for medical management are discussed.

Keywords: erectile dysfunction; ischemic priapism; medical management; recurrent priapism; sickle cell disease; stuttering priapism; therapy; treatment

PDF | 中文摘要 |

 
Browse:  1773
 
Copyright 1999-2016  Shanghai Materia Medica, Shanghai Jiao Tong University.  All rights reserved