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Volume 15, Issue 5 (September 2013) 15, 658–661; 10.1038/aja.2013.78

Penile prosthesis implantation in Chinese patients with severe erectile dysfunction: 10-year experience

Wei-Dong Song1,*, Yi-Ming Yuan1,*, Wan-Shou Cui1, Alex K Wu3, Yi-Chen Zhu1,2, Jing Liu1, Lin Wang1, Guang-Yi Bai1, Jing Peng1, Zhi-Chao Zhang1, Bing Gao1, Ying-Lu Guo1, Tom F Lue3 and Zhong-Cheng Xin1

1Andrology Center, Peking University First Hospital, Peking University, Beijing 100034, China
2Department of Urology, Beijing Youyi Hospital, Beijing Capital University, Beijing 100050, China
3Department of Urology, University of California, San Francisco, CA 94143, USA

Correspondence: Dr ZC Xin, (xinzc@bjmu.edu.cn); Dr TF Lue, (tlue@urology.ucsf.edu)

Received 28 January 2013; Revised 18 April 2013; Accepted 30 May 2013 Advance online publication 22 July 2013


We retrospectively evaluated the clinical outcome of penile prosthesis implantation (PPI) in Chinese patients with severe erectile dysfunction (SED). From July 2000 to December 2011, 224 patients (mean age: 35.9±11.8 years, range: 20–75 years) with SED underwent PPI by experienced surgeon according to standard PPI procedure at our centre. A malleable prosthesis (AMS 650) was implanted in 45 cases (20.1%), and a three-piece inflatable prosthesis (AMS 700 CXM or AMS 700 CXR) was implanted in 179 cases (79.9%). Surgical outcomes, including postoperative complications, clinical efficacy and couple satisfaction, were evaluated over than 6 months postoperatively using medical record abstraction, IIEF-5, quality of life (QoL) scores, and the patient/partner sexual satisfaction score proposed by Bhojwani et al. Of the 224 patients eligible for the study, 201 subjects (89.7%) completed follow-up. All of patients could perform sexual intercourse post PPI with the mean postoperative IIEF-5 and QoL scores were 20.02±2.32 and 5.28±0.76, respectively, which were significantly improved compared with the preoperative scores (6.29±1.5 and 2.13±0.84, P<0.01). Of the 201 men, mechanical malfunction occurred in four cases (2.0%) and three cases were re-implanted new device, and two cases (1.0%) developed a mild curvature of the penis. Scrotal erosion with infection occurred in one case with diabetes mellitus (0.5%) and required complete removal of the implanted AMS 700 CXM. Satisfactory sexual intercourse at least twice per month was reported by 178 men (88.6%), and overall satisfaction with the PPI surgery was reported by 89.0% of men and 82.5% of partners. Patient satisfaction in the three-piece inflatable prosthesis group was higher than in the malleable prosthesis group (P<0.05). Satisfaction, however, between the types of prostheses, did not differ in the partner survey. PPI is a safe and effective treatment option for Chinese patients with SED and experienced surgeon perform PPI according to standard PPI procedure could reduce the postoperative complications of PPI and could improve patient satisfaction ratio and QoL.

Keywords: complication; erectile dysfunction (ED); implantation; quality of life (QoL); penile prosthesis; satisfaction

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