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Volume 7, Issue 2 (March 2005) 7, 213–216; 10.1111/j.1745-7262.2005.00028.x
Y microdeletions in the Istria county, Croatia
I Medica, N Gligorievska, M Prenc and B Peterlin
1.Division of Medical Genetics, Department of Obstetrics and Gynecology, University Medical Centre, Ljubljana 1000, Slovenia
2.Outpatient Pediatric Clinic, Pula 52100, Croatia
3.Outpatient Infertility Clinic, Department of Gynecology, General Hospital Pula, Pula 52100, Croatia
Received: 2004-04-15 Accepted: 2004-11-12
| Abstract |
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Aim: To establish the frequency of Y chromosome microdeletions in an unselected group of infertile Croatian men.
Methods: An unselected group of 105 patients (male partners of infertile couples), both with idiopathic and non-idiopathic infertility, consecutively referred to the outpatient infertility clinic, gynecology department, General Hospital Pula, Istria County, Croatia, was examined for the presence or absence of Y chromosome microdeletions by polymerase chain reaction analysis.
Results: One of the 105 men (0.95%, 95% CI = 0.17–5.2 %) was found to have a microdeletion.
Conclusion: A low frequency of Y chromosome microdeletions was found in the group of unselected infertile Croatian men.
Keywords: male infertility, Y chromosome, AZF region, microdeletion
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