Home  |   Archive  |   Online Submission  |   News & Events  |   Subscribe  |   APFA  |   Society  |   Contact Us  |   中文版

Ahead of print
Authors' Accepted
Current Issue
Special Issues
Browse by Category

Manuscript Submission

Online Submission
Online Review
Instruction for Authors
Instruction for Reviewers
English Corner new!

About AJA

About AJA
Editorial Board
Contact Us

Resources & Services

Email alert

Download area

Copyright licence
EndNote style file
Manuscript word template
Guidance for AJA figures
    preparation (in English)

Guidance for AJA figures
    preparation (in Chinese)

Proof-reading for the

AJA Club (in English)
AJA Club (in Chinese)


Volume 17, Issue 6 (November 2015) 17, 961–971; 10.4103/1008-682X.159721

Transcriptome research on spermatogenic molecular drive in mammals

Zi-Jue Zhu, Shi Yang, Zheng Li

Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127; Department of Andrology, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080; Shanghai Key Laboratory of Reproductive Medicine, Shanghai 200025, China

Correspondence: Prof. Z Li



It is known that spermatogenic disorders are associated with genetic deficiency, although the primary mechanism is still unclear.
It is difficult to demonstrate the molecular events occurring in testis, which contains germ cells at different developmental stages.
However, transcriptomic methods can help us reveal the molecular drive of male gamete generation. Many transcriptomic studies
have been performed on rodents by utilizing the timing of the first wave of spermatogenesis, which is not a suitable strategy for
research in fertile men. With the development of separation methods for male germ cells, transcriptome research on the molecular
drive of spermatogenesis in human men has seen great progress, and the results could be ultimately applied to improve the
diagnosis and treatment for male infertility.

Full Text | PDF | 中文摘要 |

Browse:  2111
Copyright 1999-2017  Shanghai Materia Medica, Shanghai Jiao Tong University.  All rights reserved