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Volume 22, Issue 2 (March 2020) 22, 158–161; 10.4103/aja.aja_55_19

Prostate cancer risk prediction models in Eastern Asian populations: current status, racial difference, and future directions

Bi-Ming He, Rui Chen, Tian-Qi Sun, Yue Yang, Chun-Lei Zhang, Shan-Cheng Ren, Xu Gao, Ying-Hao Sun

Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China

Correspondence: Dr. YH Sun (sunyhsmmu@126.com) or Dr. X Gao (gaoxu.changhai@foxmail.com)



Prostate cancer (PCa) risk calculators (RCs) with prostate-specific antigen (PSA) and other risk factors can greatly improve the accurate prediction of potential risk of PCa compared to PSA. The European Randomized Study of Screening for PCa Risk Calculator (ERSPC-RC) and the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) are developed on the Western population. However, the Western RCs showed limited diagnostic efficacy in the Eastern Asian population, mainly due to racial differences between the two populations. We aimed to review the application of Western RCs and Eastern Asian RCs in Eastern Asian cohorts and to identify the characteristics and efficacy of these RCs.

Keywords: Asians; nomogram; prediction models; prostate cancer; risk prediction

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