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Volume 17, Issue 3 (May 2015) 17, 421–426; doi: 10.4103/1008-682X.148073
Germline-competent stem cell in avian species and its application
Jae Yong Han1, Hyung Chul Lee1, Tae Sub Park2
1 Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Korea.
2 Graduate School of International Agricultural Technology and Institute of Green-Bio Science and Technology, Seoul National University, Pyeongchang-gun, Gangwon-do 232-916, Korea.
Correspondence: Dr. JY Han (jaehan@snu.ac.kr)
2015-2-6
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Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline‑competent stem cells can self‑renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline‑competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline‑competent stem cells from avian species, mainly chicken germline‑competent stem cells, which have been well established and characterized. We discuss different sources of germline‑competent stem cells and recent advances for the future applications in birds
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