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Volume 1, Issue 3 (September 1999) 1, 127–129;
Ureaplasma urealyticum infection and apoptosis of spermatogenic cells
X.J. Shang, Y.F. Huang, C.L. Xiong, J.P. Xu, L. Yin, C.C. Wan
1.Center of Reproductive Medicine, Tongji Medical University, Wuhan 430030, China
2.Department of Reproduction and Genetics, Medical Laboratory Science Center, Jinling Hospital, Nanjing 210002, China
Advance online publication 1 September 1999
| Abstract |
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Aim: To study the relationship between Ureaplasma urealyticum (UU) infection and apoptosis of human spermatogenic cells. Methods: Spermatogenic cells were observed under light microscope with Wright-Giemsa staining and by means of terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate (dUTP)-biotin nick-end labeling (TUNEL) technique. Results: Apoptotic rate of UU-infected males (15.5%6.8%) was significantly higher than that of controls (5.2%2.3%). Conclusion: Apoptosis of spermatogenic cells can be caused by UU infection, which provides further evidence for UU-induced male infertility.
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