Aim: To assess the protective efficacy of vitamin E to counteract the reactive oxygen species (ROS) mediated damage on sperm motility, viability and lipid peroxidation. Methods: Human semen samples were obtained from the local hospital. The split seminal fractions freed of seminal plasma were reconstituted in Ringer-Tyrode and subjected to varied vitamin E concentrations (0.1-2 mmol/L). Results: Dose-dependent improvement in both motility and viability accompanied by concomitant decrease in malondialdehyde (MDA—an end product of lipid peroxidation) following vitamin E supplementation was noticed. Conclusion: Vitamin E protects against the ROS mediated damage on spermatozoa. Vitamin E supplementation could be of clinical importance for prolonged spermatozoal storage whenever needed

Full Text |