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Volume 6, Issue 1 (March 2004) 6, 71–74;
Contraceptive effect of Curcuma longa (L.) in male albino rat
Purohit Ashok, Bhagat Meenakshi
Reproductive Physiology Section, Department of Zoology, JNV University, Jodhpur (Raj.) 342 005, India
Correspondence: Dr. Ashok Purohit, E-mail: purohit1411@yahoo.com, meenakshi1910@yahoo.com
Received 2003-06-24 Accepted 2003-09-28
| Abstract |
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Aim: To study the contraceptive effect of the crude extracts of Curcuma longa in male albino rats. Methods: Rats were fed orally with Curcuma longa aqueous and 70 % alcoholic extract for 60 days (500 mg·kg-1·day-1). Results: A reduction in sperm motility and density was observed in both the treated groups. Conclusion: Curcuma longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypothalamus pituitary axis and as a result, spermatogenesis is arrested.
Keywords: Leydig cells; Curcuma longa; seminiferous tubules; antiandrogens; spermatozoa; male contraception
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