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Volume 6, Issue 3 (September 2004) 6, 233–235;
Effect of sildenafil citrate on penile erection of rhesus macaques
X.B. Huang, C.L. Xiong, C.G. Yu, J.L. Zhou, J.Y. Shen
Center for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hang Kong Road, Wuhan 430030, China
Advance online publication 1 September 2004
| Abstract |
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Aim: To examine the effect of sildenafil citrate on penile erection of male rhesus macaque. Methods: Twenty Macaca mulatta were divided into the sildenafil treated and the control groups of 10 animals each. The penile size, the corpus cavernosal electromyogram (EMG) and the intra-corpus cavernosal pressure (ICP) were determined. Results: The diameter of penis and the ICP were significantly increased and the corpus cavernosal EMG significantly reduced in the sildenafil group. Conclusion: Sildenafil citrate increases the penile size and ICP and reduces the corpus cavernosal EMG in male rhesus macaque.
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