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中文摘要

《亚洲男性学杂志》 2012; 14 (6): 875-878

男性睾酮与冠状动脉粥样硬化严重程度成负相关

Li Li, Chang-Yan Guo, En-Zhi Jia, Tie-Bing Zhu, Lian-ShengWang, Ke-Jiang Cao, Wen-Zhu Ma and Zhi-Jian Yang (中国)

本研究主要确定血浆睾酮水平是否与冠状动脉粥样硬化严重程度有关,研究对象是803个冠状动脉造影的男性患者。根据睾酮的三分位点将患者分成三组。冠状动脉粥样硬化程度由Gensini score评估。且所有人根据Gensini score中位数分成两组(≤26 和 >26)。睾酮水平通过ELASA法测定。结果睾酮与Gensini score呈负相关,多元线性回归显示睾酮是Gensini score的独立危险因子。多元logistic回归显示睾酮水平越高,冠状动脉严重度越低。结论:在803个冠状动脉造影的患者中,睾酮水平越低,Gensini score越高。但需进一步研究阐述其潜在的机制。

关键词:冠状动脉疾病,Gensini score,睾酮

此摘要文献来源:
Li Li, Chang-Yan Guo, En-Zhi Jia, Tie-Bing Zhu, Lian-ShengWang et al. Testosterone is negatively associated with the severity of coronary atherosclerosis in men. Asian J Androl 2012; 14: 875-8.

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.