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中文摘要

《亚洲男性学杂志》 2011; 13 (6): 898-902

《亚洲男性学杂志》 2011; 13 (6): 898-902

中国老年男性脱氢表雄酮水平低与抑郁症状相关:一项大型研究的结果

Samuel YS Wong, Jason C Leung, Timothy Kwok, Claes Ohlsson, Liesbeth Vandenput, Ping C Leung and Jean Woo (中国香港)

本文研究了中国老年男性的抑郁症状与睾酮总量、脱氢表雄酮(DHEA )、硫酸脱氢表雄酮(DHEAS )、雌二醇、性激素结合球蛋白(SHBG )以及游离雄激素指数之间的关系。研究采用了来自1147 名社区居住、年龄大于或等于65 周岁的老年男性的横截面数据。用中国老年抑郁量表(GDS )测量抑郁症状。同时测量了睾酮总量、游离睾酮、DHEA 、DHEAS 、雌二醇总量、游离雄激素指数以及SHBG 水平。研究表明,GDS 分值与DHEA 水平显著相关,有和DHEAS 相关的趋势,但是显著性无统计学意义(β=-0.110, P=0.015; β=-0.074, P=0.055 )。但是抑郁症状和睾酮总水平、游离睾酮水平、雌二醇水平及SHBG 水平均无相关性。关于临床相关抑郁症状, 性类固醇激素水平处于下四分位数的病人和处于其他四分位数的病人之间无显著差异。我们的研究结果与西方的研究相似,表明DHEA 和DHEAS 水平与抑郁症状相关。

关键词:中国,脱氢表雄酮,抑郁,老年男性,睾酮

此摘要文献来源:
Samuel YS Wong, Jason C Leung, Timothy Kwok, Claes Ohlsson, Liesbeth Vandenput, Ping C Leung and Jean Woo. Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study. Asian Journal of Andrology 2011; 13: 898-902

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.