Home  |   Archive  |   Online Submission  |   News & Events  |   Subscribe  |   APFA  |   Society  |   Contact Us  |   中文版
Search   
 
Journal

Ahead of print
Authors' Accepted
    Manuscripts
new!
Current Issue
Archive
Acknowledgments
Special Issues
Browse by Category

Manuscript Submission

Online Submission
Online Review
Instruction for Authors
Instruction for Reviewers
English Corner new!

About AJA

About AJA
Editorial Board
Contact Us
News

Resources & Services

Advertisement
Subscription
Email alert
Proceedings
Reprints

Download area

Copyright licence
EndNote style file
Manuscript word template
Guidance for AJA figures
    preparation (in English)

Guidance for AJA figures
    preparation (in Chinese)

Proof-reading for the
    authors

AJA Club (in English)
AJA Club (in Chinese)

 
中文摘要

《亚洲男性学杂志》 2013; 15 (4): 533-538

治疗男方因素不育的双次宫内授精与单次宫内授精的比较:系统综述及荟萃分析

Apostolos Zavos, Alexandros Daponte, Antonios Garas, Christina Verykouki, Evangelos Papanikolaou, Georgios Anifandis and Nikolaos P Polyzos (希腊,比利时)

男性因素不育影响着全球30%–50%的不育夫妇,越来越多人开始关注优化管理这些病人。本文比较了双次与单次宫内授精的结局,观察到在男性因素不育的夫妻中存在着一个比较高的妊娠率趋势。因此,我们用荟萃分析比较了男性因素不育夫妇中双次子宫内授精和单次子宫内受精的优越性。95%的置信区间比值用来检测受孕率。根据结果的异质性选用Mantel–Haesel 或 DerSimonian–Laird 模型分析。共五个试验含1125个宫内受精周期纳入荟萃分析。一个周期的双次子宫内授精妊娠率比一个周期单次的高两倍(OR: 2.0; 95% CI: 1.07–3.75; P<0.03)。然而,这些结果得益于大量实验,使得加权值约在50%左右。灵敏度分析,不包括大样本试验,显示双次子宫内授精的夫妇存在高妊娠率的趋势,但无统计学意义(P=0.20)。我们的系统分析强调,在男性因素不育夫妇中运用双IUI的证据还不完全还很薄弱。尽管随着子宫内受精周期数的增多,妊娠率有上升趋势,但还需要更大量及精心设计的试验为临床应用提供可靠证据。

关键词:同源性,子宫内受精,男性不育,荟萃分析,系统性评论
此摘要文献来源:
Apostolos Zavos, Alexandros Daponte, Antonios Garas, Christina Verykouki, Evangelos Papanikolaou et al. Double versus single homologous intrauterine insemination for male factor infertility: a systematic review and meta-analysis. Asian J Androl 2013; 15: 533-8.

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.