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中文摘要

《亚洲男性学杂志》 2013; 15 (6): 759-763

老年前列腺癌伴骨转移患者的临床特征及治疗策略
Cheng Yang, Gui-Sheng Qi, Rui-Ming Rong and Jian He(中国)

为确定老年前列腺癌伴骨转移患者的临床特征及预后的独立预测因子。本研究回顾性分析了205例老年性前列腺癌伴骨转移患者的临床资料,运用生存曲线分析生存率,运行Cox回归模型进行多因素分析。同时,我们对比了197例年轻的前列腺癌伴骨转移的患者,运用卡方检验比较了上述得到的预测因子。结果显示,所有患者均得到完整随访,其1、2、3和5年生存率分别为95.5%, 77.5%, 68.5% 和 33.7%。Gleason评分,原发肿瘤放疗、骨转移数目、ALP、器官和区域淋巴结转移数目均与生存率密切相关。多因素回归分析表明Gleason评分是独立预测因子。相较于年轻患者,老年患者生存率更好,但是接受放疗的老年患者生存率却显著低于年轻患者。以上结果为今后前列腺癌伴骨转移生存预测模型的建立提供了数据支持。

关键词:骨转移,老年,预后分析,前列腺癌,临床特征

此摘要文献来源:
Cheng Yang, Gui-Sheng Qi, Rui-Ming Rong, Jian He. Clinical features and treatment strategies for older prostate cancer patients with bone metastasis. Asian J Androl 2013;15: 759–763.

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.