Home  |   Archive  |   Online Submission  |   News & Events  |   Subscribe  |   APFA  |   Society  |   Contact Us  |   中文版
Search   
 
Journal

Ahead of print
Authors' Accepted
    Manuscripts
new!
Current Issue
Archive
Acknowledgments
Special Issues
Browse by Category

Manuscript Submission

Online Submission
Online Review
Instruction for Authors
Instruction for Reviewers
English Corner new!

About AJA

About AJA
Editorial Board
Contact Us
News

Resources & Services

Advertisement
Subscription
Email alert
Proceedings
Reprints

Download area

Copyright licence
EndNote style file
Manuscript word template
Guidance for AJA figures
    preparation (in English)

Guidance for AJA figures
    preparation (in Chinese)

Proof-reading for the
    authors

AJA Club (in English)
AJA Club (in Chinese)

 
中文摘要

《亚洲男性学杂志》 2013; 15 (6): 790-794

《亚洲男性学杂志》 2013; 15 (6): 790–794

精子DNA完整性与形态超高倍检测在辅助生殖技术妊娠结局中的临床价值
Gemma López, Rafael Lafuente, Miguel A. Checa, Ramón Carreras and Mario Brassesco(西班牙)

近年来,涌现出许多重要的男性不育诊疗新技术。本研究旨在探讨精子DNA完整性与精子空泡率检测对以男性不育因素行IVF或ICSI治疗的不育症的治疗结局。本研究针对152对不育症夫妻行ART技术前进行的精子DNA碎片率与形态学超高倍分析进行队列研究。我们发现对妊娠结局最有预测价值的DNA碎片率切点值为25.5%,阴性预测值为72.7%(P=0.02)。在对空泡率的研究中发现,3、4级的空泡精子的最有预测价值切点值为73.5%,阴性预测值为39.4% (P=0.09),差异无统计学意义。总之,当精子DNA碎片率大于25%时,IVF失败的概率增大,而精子形态学超高倍检测结果对预测患者的妊娠结局无明显获益。

关键词:DNA 碎片率,超高倍检测,IVF, 空泡率

此摘要文献来源:
Gemma López, Rafael Lafuente, Miguel A. Checa, Ramón Carreras, Mario Brassesco. Diagnostic value of sperm DNA fragmentation and sperm high-magnification for predicting outcome of assisted reproduction treatment. Asian J Androl 2013;15: 790–794.

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.