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中文摘要

《亚洲男性学杂志》 2014; 16 (4): 549-554

【特刊综述】目前前列腺癌早期诊断的生物指标

前列腺癌正在成为西方国家发病率第一,死亡率第二的疾病,极大程度地危害着男性健康。过往几十年间,虽然前列腺特异性抗原(PSA)的问世很好地辅助了前列腺癌的诊断,但是由于其较低的特异性,导致了健康人群的过度诊断和患者的过度治疗。因此,我们需要挖掘更多微创的甚至无创的有效指标来辅助前列腺癌的临床诊断,从而指导患者进行早期的治疗以降低疾病死亡率。此篇综述详尽地描述和总结了除PSA之外现有的前列腺癌诊断指标,并总结了这些生物标记的优缺点。

关键词:早期诊断标记,源于MALAT1的小RNA,PCA3,前列腺癌,PSA

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.