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中文摘要

《亚洲男性学杂志》 2016; 18 (2): 194-201

【特刊综述】精索静脉曲张治疗的青少年与成年人精浆的蛋白质组学研究
精索静脉曲张是男性不育症的最重要因素,存在于15%的成年男性中,其中35%的男性为原发性不育症,80%的男性为继发性不育症。另一方面,这些男性中有80%具有生育力。因此需要寻找一种方法能够将对身体有害和对身体无害的精索静脉曲张疾病区分开。尽管精索静脉曲张细胞学效应的理论依据逐渐增多,但它最根本的分子学机制仍然未知。蛋白质组学是确定精子生殖生物学以及提高男性不育症诊断的很有前景的研究领域。这篇综述旨在讨论精索静脉曲张病人等离子体蛋白质组学的技术发展,并讨论从事这些研究的挑战性以及精液蛋白质组学理论研究的未来展望。
关键词:男性不育症;蛋白质组学;精浆;精索静脉曲张;精索静脉曲张切除术

 
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