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中文摘要

《亚洲男性学杂志》 2007; 9 (2): 229-233

《亚洲男科学杂志》 2007; 9(2): 229-233

【论著】良性前列腺肥大、非典型腺瘤性增生和潜伏性前列腺癌的关联

Konstantinos Stamatiou, Alevizos Alevizos, Mohamed Natzar, Constantinos Mihas, Anargiros Mariolis,
Emmanouel Michalodimitrakis, Fragiskos Sofras(希腊)

目的:利用尸检材料研究非典型腺瘤性增生(atypical adenomatous hyperplasia,AAH)、良性前列腺肥大(benign prostate hypertrophy,BPH)和潜伏性前列腺组织癌(latent histological carcinoma of the prostate, LPC)之间的关联。方法:本研究对212个尸检前列腺标本进行全程分析以探讨BPH、AAH、LPC之间的关联。结果:在严重增生的前列腺样本中检测到大部分组织癌和AAH损伤。肿瘤体积、组织学分化和生物学行为等BPH与LPC的主要特征之间无显著统计学关联。多病灶肿瘤的数据显示多病灶癌和AAH损伤趋向于在较大的前列腺中发展。AAH和LPC之间无显著统计学相关。结论:AAH损伤和前列腺腺癌之间似乎无任何病原病理遗传学和部位型联系。AAH损伤似乎及其类似于前列腺腺癌,已报道的AAH与前列腺癌之间的关联可能只是一种副现象。

关键词:非典型腺瘤性增生;组织学前列腺癌;良性前列腺增生

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.