Dr. Elisabetta Baldi

March 1979: Graduated in Biological Science in the University of Florence with 110/110 cum laude.
1979-1984: post-doctoral fellowship in the Institute of Clinical Pharmacology of the University of Florence.
April-May 1980: visiting scientist in the Laboratory of Biochemistry of the Imperial College of Science and Tachnology (London), directed by Dr. J. Hughes after winning a Wellcome Research Travel Grant for two months. During this visit she learns methods of biological assays.
November 1981: win a grant from Italian National Research Council (CNR Rome) for three years.
March-April 1982: visiting fellow in the Laboratory of preclinical Pharmacology of the National Institute of Health (Washington, USA) directed by Prof. E. Costa to learn HPLC techniques.
November 1982: admitted to the post-graduate course in pharmacology at the University of Milan (Prof. F. Berti)
November 1984: Specialized in Pharmacology at the University of Milan (70/70).
1984: The Grant from CNR is renewed. She become intern in the Laboratory of Endocrinology of the University of Florence directed by Prof. MSerio.
1988-1990: two years research fellowship in the Laboratory of Nephrology directed by Prof. M. Dunn at Case Western Reserve University (Cleveland, Ohio).
July 1990-2001: Researcher in the Andrology Unit of the University of Florence directed by prof. G. Forti.
January 2002: win a position of Researcher in the University of Florence.
May 2005 - Present : Associate Professor in Clinical Pathology (MED/05)

Scientific Awards
-Win several National and International awards
-Invited speaker in more than 100 International and National Congress

Editorial and other activities
-Managing Editor of the Journal Frontiers in Bioscience
-Member of the Board of Reproductive Toxicology and Reproductive Biology and Endocrinology
-Editorial Board di Reproductive Toxicology (2005-2007)
-Associate Editor Andrology (2012-)
-Associate Editor the scientific world journal (2012-)
-Associate Editor World journal of translational (2012-)
-Editor of Frontiers in Endocrinology
-Member of the board of the Journal Hormone
-Co-Editor with M. Muratori of the E-Book springer: "Damage in the genetic material of human spermatozoa: relation to fertility" (2013)
-Journal of Reproductive Immunology (guest editor of the special issue on male genital tract infection and infertility, 2013)
-Scientific Committee International Meetings Rapid Actions of Steroid Hormones (2001-2010)
-Member of the International Liaison Committee (American Society of Andrology)
-Member of the Award Committee (American Society of Andrology)
-Member of the Programme Organizing Committee of European Congress of Andrology in 2006 and 2010.
-Referee of grant proposal (including the Wellcome and the ONHMRC-Grant-Net (Australia), University of Milan, Science Foundation of Ireland, National Medical Research Council of Singapore)
-Referee of several International Journals

Financied Projects
-PRIN 2007-2010: Unit responsible (49.714 €)
-PRIN 2009-2013: Unit responsible (93000 €)
-Ministry of Health: Integrated programs in oncologic research 2006: participant (50000 €)
-FIRB 2010 to Sara Marchiani (total funding: 853000, participant)
-Project Serono: Significance of the polymorphism p.N680S for the efficacy of FSH therapy of idiopathic male infertility: a pharmacogenetic approach (10.000€)

Actual fields of research
-Sperm Biology: capacitation, acrosome reaction, motility. Nongenomic effects of steroid hormones. New predictive parameters of fertility status. Investigation on the origin and the consequences on reproduction of sperm DNA fragmentation. Role of the calcium channel CatSper in sperm function.
-Prostate cancer cell biology, study of the mechanisms that regulate invasion and development of androgen resistence

Publications

1. Anselmi B, Baldi E, Casacci F, Salmon S. Endogenous opioids in cerebrospinal fluid and blood of idiopathic headache sufferes. Headache, 1980;20: 294-299. Questo lavoro e'stato insignito del 15° Harold Wolff Lecture Award.
2. Baldi E, Salmon S, Anselmi B, Spillantini M.G, Cappelli G, Brocchi A, Sicuteri F. Intermittent hypoendorpinemia in migraine attack. Cephalalgia, 1982;2:77-82.
3. Panero C, Cosenza-Biagioli E, Baldi E, Spillantini M.G, Cianciulli D, Carbone C, Mainardi G, Bettini F. Plasma beta-endorphin in normal and premature newborns. J Fetal Med, 1984;V:1-5.
4. Baldi E, Conti P, Conti R, Fanciullacci M, Michelacci S, Salmon S, Sicuteri F, Spillantini MG. Hypernociceptive syndromes and pharmacological inhibition of endogenous opioid degradation. Int. J. Clin. Pharmacol. Res, 1986;VI(3):193-197.
5. Caldini AL, Orlando C, Barni T, Messeri G, Pazzagli M, Baldi E, Serio M. Measurament of transferrin in human seminal plasma by a chemiluminescent method. Clin. Chem. 1986;32/1:153-156.
6. Mannelli M, Maggi M, De Feo ML, Boscaro M, Opocher G, Mantero F, Baldi E, Giusti G. Opioid modulation of normal and pathological chromaffin tissue. J. Clin. Endocrinol. Metab. 1986;62(3):577-592.
7. Mannelli M, De Feo M.L, Maggi M, Geppetti P, Baldi E, Pupilli C, Serio M. Effect of verapamil on catecholamine secretion by human pheaochromocytoma. Hypertension, 1986;8(9):813-814.
8. Baldi E, Spillantini MG, Cosenza-Biagioli E, Mainardi G, Cianciulli D, Carbone C, Panero C. Met-enkephalin-like immunoreactivity (ME-LI) and enkephalinase activity (EKA) in cord blood and newborns in the first hours of life. Biol. Res. Pregnancy Perinatol. 1986;7 (2):84-88.
9. Mannelli M, De Feo M. L, Maggi M, Opocher G, Valenza T, Baldi E, Serio M. Usufulness of basal catecholamies plasma levels and clonidine suppression test in the diagnosis of pheochromocytoma. J Endocrinol Invest, 1987;10:377.
10. Baldi E, De Feo M. L, Geppetti P, Carla' V, Maggi M, Pupilli C, Spillantini M. G, Brocchi A, Mannelli M. Measurament of catecholamines, met-enkephalin-, somatostatin-and substance P-like immunoreactivities in 12 human pheochromocitoma. J Endocrinol Invest, 1987;11(2) :133-138.
11. Baldi E, Pupilli C, Amenta F, Mannelli M. Presence of a dopamine-dependent adenylate cyclase activity in human renal cortex. Eur. J. Pharmacol. 1987;149:351-356.
12. Maggi M, Genazzani AD, Giannini S, Torrisi C, Baldi E, Di Tommaso M, Munson P, Rodbard D, Serio M. Vasopressin and oxytocin receptors in vagine, myometrium and oviduct of rabbits. Endocrinology, 1988;122:2970-2980.
13. Maggi CA, Santicioli P, Patacchini R, Geppetti P, Giuliani S, Astolfi M, Baldi E, Parlani M, Theodorsson E, Fusco B, Meli A. Regional differences in the motor response to capsaicin of the guinea pig urinary bladder: relative role of pre-and post-junctional factors related to neuropeptide-containing sensory nerves. Neuroscience , 1988;27(2) :675-688.
14. Laffi G, Pinzani M, Meacci M, La Villa G.,Renzi D, Baldi E, Cominelli F, Marra F, Gentilini P. Renal hemodynamic and natriuretic effects of atrial netriuretic factor infusion in cirrhosis with ascites. Gastroenterology, 1989;96:167-177.
15. Geppetti P, Baldi E, Castellucci A, Del Bianco E, Santicioli P, Maggi CA, Lippe IT, Amman R, Skofisch G, Theodorsson E, Manzini S. Calcitonin-gene related peptide in the rat kidney: occurence, sensitivity to capsaicin and stimulation of adenylate cyclase. Neuroscience, 1989;30(2) 503-513.
16. Geppetti P, Baldi E, Manzini S, Del Bianco E, Maggi CA, Natali A, Mannelli M. Regional differences of adenylate cyclase stimulation by calcitonin and calcitonin-gene related peptide (CGRP) in the human kidney. J Clin Endocrinol Metab, 1989;69(2):491-495.
17. Maggi M, Baldi E, Genazzani AD, Giannini S, Natali A, Costantini A, Rodbard D, Serio M. Vasopressin reseptors in human seminal vesicles: identification, pharmacologic, characterization and comparison with the vasopressin receptors present in the human kidney. J Androl, 1989;10:393-400.
18. Baldi E, Emancipator SN, Hassan MO, Dunn MJ. Platelet activating factor receptor blockade ameliorates murine systemic lupus erythematosus. Kidney International, 1990;38:1030.
19. Baldi E, Dunn MJ. Endothelin binding and receptor down regulation in rat glomerular mesangial cells. J Pharmacol Exp Therap. 1991;256(2):581-586.
20. Baldi E, Casano R, Falsetti C, Krausz C, Maggi M, Forti G. Intracellular calcium accumulation and responsiveness to progesterone in capacitating human spermatozoa. J Andrology, 1991;12(5) :323-330.
21. Thomas CP, Baldi E, Simonson MS, Kester M, Dunn MG. Endothelin receptors and coupled GTP-binding proteins in glomerular mesangial cells. J Cardiovascular Pharmacol. 1991;17 (suppl. 7):S79-S84.
22. Villani A, Cirino NM, Baldi E, Kester M, McFadden ER, Panuska JR. Respiratory syncytial virus infection of human mononuclear phagocytes stimulates synthesis of platelet activating factor. J Biol Chem. 1991;266 (9):5472-5479.
23. Kester M, Simonson MS, MCDermott R. G, Baldi E, Dunn M. J. Endothelin stimulates phosphatidic acid formation in cultured rat mesangial cells: role of a protein kinase c-regulated phospholipase D. J Cell Physiol. 1992;150:578-585.
24. Pinzani M, Failli P, Ruocco C, Casini A, Milani S, Baldi E, Giotti A, Gentilini P. Fat-storing cells as liver-specific pericytes, spatial dynamics of agonist-stimuiated intracellular calcium transients. J Clin Invest. 1992;90: 642-646.
25. Simonson MS.,Kester M, Baldi E, Osanai T, Thomas CP, Mené P, Dunn MJ. Endothelins:renal and cardiovascular actions. Adv Nephrol. 1992;21:177-191.
26. Falsetti C, Baldi E, Krausz C, Casano R, Failli P, Forti G. Decreased responsiveness to progesterone in oligozoospermic patients. J Androl, 1993;14:17-22.
27. Baldi E, Falsetti C, Krausz, Cs, Gervasi G, Carloni V, Forti G. Stimulation of platelet-activating factor synthesis by progesterone and A23187 in human spermatozoa. Biochem J. 1993;292:209-216.
28. Maggi M, Fantoni G, Peri A, Rossi S, Baldi E, Magini A, Massi G, Serio M. Oxytocinendothelin interactions in the uterus. Regul Pept, 1993;45:97-101.
29. Laffi G, Carloni V, Baldi E, Rossi M.E, Azzari C, Gresele P, Marra F, Gentilini P. Impaired superoxide anion, platelet-activating factor, and leukotriene B4 synthesis by neutrophils in Cirrhosis. Gastroenterology, 1993;105:170-177.
30. M. Maggi, Baldi E, Finetti G, Franceschelli F, Brocchi A, Lanzillotti R, Serio M, Camboni MG, Thiele CJ. Identification, characterization, and biological activity of somatostatin receptors in human neuroblastoma cell lines. Cancer Res, 1994;54:124-133.
31. Baldi E, Musial A, Kester M. Endothelin stimulates phosphatidylcholine hydrolysis through both phospholipase C and D pathways in cultured rat mesangial cells. Am J Physiol. (Renal and Electrolyte Physiology), 1994;266:F957-F965.
32. Krausz CS, Gervasi G, Forti G, Baldi E. Effect of platelet-activating factor on motility and acrosome reaction of human spermatozoa. Human Reproduction, 1994;9:471-476.
33. Baldi E, Bonaccorsi L, Finetti G, Luconi M, Muratori M, Susini T, Forti G, Serio M, Maggi M. Platelet-activating factor in human endometrium. J Steroid Biochem Mol Biol. 1994 Jun;49(4-6):359-63.
34. Maggi M, Fantoni G, Baldi E, Cioni A, Rossi S, Vannelli GB, Melin P, Akerlund M, Serio M. Antagonists for the human oxytocin receptor: an in vitro study. J Reprod Fertil, 1994;101:345-352.
35. Maggi M, Vannelli GB, Fantoni G, Baldi E, Magini A, Peri A, Giannini S, Gloria L, Del Carlo P, Casparis D, Tomei T, Serio M. Endothelin in the human uterus during pregnancy. J Endocrinol, 1994;142:385-396.
36. Maggi M, Bonaccorsi L, Finetti G, Carloni V, Muratori M, Laffi G, Forti G, Serio M, Baldi E. Platelet-activating factor mediates an autocrine proliferative loop in the endometrial adenocarcinoma cell line HEC-1A. Cancer Res, 1994;54:4777-4784.
37. Krausz CS, Bonaccorsi L, Luconi M, Fuzzi B, Criscuoli L, Pellegrini S, Forti G, Baldi E. Intracellular calcium increase and acrosome reaction in response to progesterone in human spermatozoa is correlated with in vitro fertilization. Human Reprod. 1995;10: 120-124.
38. Maggi M, Baldi E, Susini T. Hormonal and local regulation of uterine activity during parturition: part I -the oxytocin system. J. Endocrinol. Invest, 1994;17:739-756.
39. Maggi M, Baldi E, Susini T. Hormonal and local regulation of uterine activity during parturition: part II -the prostaglandin and adrenergic systems. J. Endocrinol. Invest, 1994;17:757-770.
40. Luconi M, Bonaccorsi L, Krausz CS, Gervasi G, Forti G, Baldi E. Stimulation of protein tyrosine phosphorylation by platelet-activating factor and progesterone in human spermatozoa. Molec. Cell. Endocrinol, 1995;108:35-42.
41. Maggi M, Finetti G, Cioni A, Mancini R, Baldi E, Serio M, Catalioto RM, Renzetti AR. Identification and characterization of functional angiotensin II receptors in human neuroblastoma cells. Regul Pept, 1995;56,175-184.
42. Bonaccorsi L, Luconi M, Forti G, Baldi E. Tyrosine kinase inhibition attenuates the plateau phase of calcium increase in response to progesterone in human spermatozoa. FEBS Letter, 1995;364,83-86.
43. Baldi E, Krausz CS, Luconi M, Bonaccorsi L, Maggi M, Forti G. Actions of progesterone on human sperm: a model of non genomic effects of steroids. J Steroid Biochem Molec Biol, 1995;53, 199-203.
44. Baldi E, Krausz CS, Forti G. Nongenomic actions of progesterone on human spermatozoa. Trends in Endocrinology and Metabolism, 1995;6, 198-205.
45. Giannini S, Maggi M, Cresci B, Finetti G, Bonaccorsi L, Luconi M, Rotella C.M, Forti G, Serio M, Baldi E. Platelet-activating factor enhances production of insulin-like grwoth factor binding proteins in a human adenoacrcinoma cell line (HEC-1A). Gynecol. Oncol, 1996;61, 333-340.
46. Luconi M, Krausz CS, Forti G, Baldi E. Extracellular calcium negatively modulates tyrosine phosphorylation and tyrosine kinase activity during capacitation of human spermatozoa. Biol Reprod, 1996;55, 207-216.
47. Krausz CS, Bonaccorsi L, Maggio P, Luconi M, Criscuoli L, Fuzzi B, Pellegrini S, Forti G, Baldi E. Two functional assays of sperm responsiveness to progesterone and their predictive values in in vitro fertilization. Human Reprod, 1996;11, 1661-1667.
48. Baldi E, Luconi M, Bonaccorsi L, Krausz CS, Forti G. Human sperm activaiton during capacitation and acrosome reaction: role of calcium, protein phosphorylation and lipid remodelling pathways. Frontiers Biosci, 1996;1, d189-205.
49. Maggi M, Peri A, Baldi E, Mancina R, Granchi S, Fantoni G, Finetti G, Forti G, Casini Raggi C, Serio M. Interferon-α down regulates expression of the oxytocin receptor in cultured human myometrial cells. Am J Physiol, 1996;271, E840-E846.
50. Bonaccorsi L, Luconi M, Maggi M, Muratori M, Forti G, Serio M, Baldi E. Protein tyrosine kinase, mitogen activated protein kinase and protein kinase C are involved in the mitogenic signaling of platelet-activating factor (PAF) in HEC-1A cells. Biochim Biophys Acta, 1997;1355, 155-166.
51. Luconi M, Krausz C, Barni T, Vannelli G.B, Forti G, Baldi E. Progesterone stimulates p42 extracellular-signal regulated kinase (p42ERK) in human spermatozoa. Molec Hum Reprod, 1998;4, 251-258.
52. Luconi M, Bonaccorsi L, Maggi M, Pecchioli P, Krausz C, Forti G, Baldi E. Identification and characterization of functional nongenomic progesterone receptors on human sperm membranes. J Clin Endocrinol Metab, 1998;83, 847-855.
53. Bonaccorsi L, Krausz C, Pecchioli P, Forti G, Baldi E. Progesterone-stimulated intracellular protein kinase C in human spermatozoa is calcium-independent. Molec Hum Reprod, 1998;4, 259-268.
54. Luconi M, Barni T, Vannelli G.B, Krausz C, Marra F, Benedetti P.A, Evangelista V, Francavilla S, Properzi G, Forti G, Baldi E. Extracellular-signal regulated kinases modulate capacitation of human spermatozoa. Biol Reprod, 1998;58, 1476-1489.
55. Baldi E, Luconi M, Bonaccorsi L, Forti G. Nongenomic effects of progesterone on spermatozoa : mechanisms of signal transduction and clinical implications. Frontiers in Bioscience, 1998;3, d1051-d1059.
56. Forti G, Baldi E, Krausz C, Luconi M, Bonaccorsi L, Maggi M, Bassi F, Scarselli G. Effects of progesterone on human spermatozoa: clinical implications. Annals Endocrinol, 1999;60: 107-110.
57. Baldi E, Luconi M, Bonaccorsi L, Maggi M, Francavilla S, Gabriele A, Properzi G, Forti G. Nongenomic progesterone receptor in human spermatozoa: biochemical aspects and clinical implications. Steroids, 1999;64, 143-148.
58. Luconi M, Muratori M, Forti G, Baldi E. Identification and characterization of a novel functional estrogen receptor on human sperm membrane which interferes with progesterone effects. J Clin Endocrinol Metab, 1999;84, 1670-1678.
59. Baldi E, Luconi M, Bonaccorsi L, Forti G. Nongenomic effects of progesterone on spermatozoa: relevance to sperm functions. Current Topics in Steroid Res, 1999;2:119-125.
60. Bonaccorsi L, Carloni V, Muratori M, Salvadori A, Giannini A, Carini M, Serio M, Forti G, Baldi E. Androgen receptor expression in prostate carcinoma cells suppresses α6β4 integrin-mediated phenotype. Endocrinology, 2000;141:3172-3182.
61. El-Hefnawy T, Luconi M, Baldi E, Slotte P, Huhtaniemi I. Progesterone action in a murine Leydig tumor cell line (mLTC-1) possibly through a non-classical receptor type" Endocrinology, 2000;141, 247-255.
62. Luconi M, Muratori M, Maggi M, Pecchioli P, Peri A, Mancini M, Filimberti E, Forti G, Baldi E. Uteroglobin (UG) and transglutaminase modulate human sperm functions. J Androl, 2000;21, 676-688.
63. Baldi E, Luconi M, Muratori M, Forti G. A novel functional estrogen receptor on human sperm membrane interferes with progesterone effects. Mol Cell Endocrinol, 2000;161:31-35.
64. Baldi E, Luconi M, Bonaccorsi L, Forti G. Signal transduction mechanisms in human spermatozoa: from physiology to possible new therapeutic application. Emerging Therapeutic Targets, 2000;4(2): 239-253.
65. Muratori M, Piomboni P, Baldi E, Filimberti E, Pecchioli P, Moretti E, Gambera L, Baccetti B, Biagiotti R, Forti G, Maggi M. Functional and ultrastructural features of DNA-fragmented human sperm. J Androl, 2000;21: 903-912.
66. Peri A, Bonaccorsi L, Muratori M, Luconi M, Baldi E, Granchi S, Pesciullesi A, Mini E, Cioppi F, Forti G, Serio M, Maggi M. Uteroglobin reverts the transformed phenotype in the endometrial adenocarcinoma cell line HEC-1A by disrupting the metabolic pathways generating Platelet-activating factor. Int J Cancer, 2000;88: 525-534.
67. Luconi M, Bonaccorsi L, Forti G, Baldi E. Effects of estrogenic compounds on human spermatozoa: evidence for interaction with nongenomic receptor for estrogen on human sperm membrane. Mol Cell Endocrinol, 2001;178:39-45.
68. Baldi E, Luconi M, Bonaccorsi L, Forti G. Signal transduction pathways in human spermatozoa. J Reprod Immunol, 2001;53(1-2):121-31.
69. Luconi M, Marra F, Gandini L, Folimberti E, Lenzi A, Forti G, Baldi E. Phosphatidylinositol 3-kinase inhibition enhances human sperm motility. Human Reprod, 2001;16, 1931-1937.
70. Bonaccorsi L, Forti G, Baldi E. Low voltage activated calcium channels are not involved in capacitation and biological response to progesterone (P) in human spermatozoa. Int J Androl, 2001;24, 341-351.
71. Granchi S, Brocchi S, Bonaccorsi L, Baldi E, Vinci M.C, Forti G, Serio M, Maggi M. Endothelin-1 production by prostate cancer cell lines is up-regulated by factors involved in cancer progression and down regulated by androgens. Prostate, 2001;49(4):267-77.
72. Luconi M, Bonaccorsi L, Bini L, Liberatori S, Pallini V, Forti G, Baldi E. Characterization of membrane nongenomic receptors for progesterone in human spermatozoa. Steroids, 2001;67(6):505-9.
73. Luconi M, Forti G, Baldi E. Genomic and nongenomic effects of estrogens: molecular mechanisms of action and clinical implications for male reproduction. J Steroid Biochem Mol Biol. 2002 Apr;80(4-5):369-81.
74. Carloni V, Defranco RM, Caligiuri A, Gentilini A, Sciammetta SC, Baldi E, Lottini B, Gentilini P, Pinzani M. Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI3kinase activation in stellate cells. Hepatology, 2002;36:582-591
75. Rosini P, Bonaccorsi L, Baldi E, Chiasserini C, Forti G, De Chiara G, Lucibello M, Mongiat M, Iozzo R.V, Garaci E, Cozzolino F, Torcia MG. Androgen receptor expression induces FGF2, FGF-binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth survival and androgen receptor down-modulation. Prostate, 2002;53(4):310-21.
76. Muratori M, Maggi M, Spinelli S, Filimberti E, Forti G, Baldi E. Spontaneous DNA fragmentation in swim-up selected human spermatozoa during long term incubation. J Androl. 2003, 24(2):253-262.
77. Bonaccorsi L, Muratori M, Carloni V, Zecchi S, Formigli L, Forti G, Baldi E. Androgen receptor and prostate cancer invasion. Int J Androl. 2003, (1):21-5.
78. Baldi E, Bonaccorsi L, Forti G. Androgen receptor: good guy or bad guy in prostate cancer invasion? Endocrinology. 2003, 144(5):1653-1655.
79. Luconi M, Baldi E. How do sperm swim? Molecular mechanisms underlying sperm motility. Cell Mol Biol (Noisy-le-grand). 2003 ;49(3):357-69.
80. Peri A, Bonaccorsi L, Cioppi F, Muratori M, Luconi M, Granchi S, Maggi M, Baldi E. The effects of an autocrine loop mediated by platelet-activating factor (PAF)in HEC-1A cells are reverted by uteroglobin. Hum Cell. 2003;16(3):95-9.
81. SS du Plessis, DR Franken, E Baldi and M Luconi. Phosphatidylinositol 3-kinase inhibition enhances human sperm motility and sperm-zona pellucida binding. Int J Androl. 2003, 26:1-8.
82. Luconi M, Carloni V, Marra F, Ferruzzi P, Forti G and Baldi E. Increased phosphorylation of AKAP by inhibition of phosphatidylinositol 3-kinase enhances human sperm motility through tail recruitment of protein kinase A. Journal Cell Sci, 2004, 117: 1235-1246.
83. M Luconi, F Francavilla, I Porazzi, B Macerola, G Forti, E Baldi. Human spermatozoa as a model for studying membrane receptors mediating rapid nongenomic effects of progesterone and estrogens. Steroids, 2004, 69: 553-559.
84. Bonaccorsi L, Muratori M, Carloni V, Marchiani S, Formigli L, Forti G, Baldi E. The androgen receptor associates with the epidermal growth factor receptor in androgen-sensitive prostate cancer cells. Steroids, 2004, 69: 549-552.
85. Muratori M, Porozzi I, Luconi M, Marchiani S, Forti G, Baldi E. Annexin V binding and merocyaninne staining fail to detetc human sperm capacitation. J Androl, 2004, 25:797-810.
86. Bonaccorsi L, Marchiani S, Muratori M, Forti G, Baldi E. Gefitinib (Iressa, ZD1839) inhibits EGF-induced invasion in prostate cancer cells by suppressing PI3K/AKT activation. J Cancer Res. Clin. Oncol, 2004, 130:604-614.
87. Bonaccorsi L, Carloni V, Muratori M, Formigli L, Zecchi S, Forti G, Baldi E. EGF receptor (EGFR) signaling promoting invasioni s disrupted in androgen-sensitive prostate cancer cells by an interaction between EGFR and androgen receptor (AR). Int J Cancer, 2004, 112:78-86.
88. Norman AW, Wehling M, Baldi E. Overview of the third international meeting on rapid responses to steroid hormones. Steroids, 2004, 69: 515.
89. Luconi M, Porazzi I, Ferruzzi P, Marchiani S, Forti G, Baldi E. Tyrosine phosphorylation of the A-kinase anchoring protein 3 (AKAP3) and solubile adenylate cyclase are involved in the increase of human sperm motilità by bicarbonato. Biol Reprod, 2004;72(1):22-32.
90. Teodori E, Baldi E, Dei S, Gualtieri F, Romanelli MN, Scapecchi S, Bellocci C, Ghelardini C, Matucci R. Design, synthesis and preliminary pharmacological evaluation of 4aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain. J Med Chem, 2004;47, 6070-6081.
91. Muratori M, Marchiani S, Forti G, Baldi E. Sperm ubiquitination positively correlates to normal morphology in human semen. Human Reproduction, 2005;20(4):1035-43.
92. Vignozzi L, Vannelli GB, Morelli A, Mancina R, Marini M, Ferruzzi P, Crescioli C, Luconi M, Donati S, Fisher AD, Baldi E, Filippi S, Forti G, Maggi M. Identification, characterization and biological activity of oxytocin receptor in the developing human penis. Mol Hum Reprod. 2004;11(2):99-106
93. Bonaccorsi L, Marchiani S, Muratori M, Carloni V, Forti G, Baldi E. Signaling mechanisms that mediate invasion in prostate cancer cells. Ann N Y Acad Sci. 2004;1028:283-8.
94. Brewis IA, Moore HD, Fraser LR, Holt WV, Baldi E, Luconi M, Gadella BM, Ford WC, Harrison RA. Molecular mechanisms during sperm capacitation. Hum Fertil (Camb). 2005 Dec;8(4):253-61.
95. Luconi M, Torcia S, Grillo D, Fiorenza MT, Forti G, Mangia F, Baldi E. Enhancement of mouse sperm motility by the PI3-kinase inhibitor LY294002 does not result in toxic effects on preimplantation embryo development. Hum Reprod. 2005 Dec;20(12):3500-4.
96. Bonaccorsi L, Muratori M, Marchiani S, Forti G, Baldi E.The androgen receptor and prostate cancer invasioNMol Cell Endocrinol. 2006 Feb 26;246(1-2):157-62.
97. Marchiani S, Bonaccorsi L, Ferruzzi P, Crescioli C, Muratori M, Adorini L, Forti G, Maggi M, Baldi E. The vitamin D analogue BXL-628 inhibits growth factor-stimulated proliferation and invasion of DU145 prostate cancer cells. J Cancer Res Clin Oncol. 2006 Jun;132(6):408-16.
98. Muratori M, Marchiani S, Maggi M, Forti G, Baldi E. Origin and biological significance of DNA fragmentation in human spermatozoa. Front Biosci. 2006 May 1;11:1491-9.
99. Luconi M, Forti G, Baldi E. Pathophysiology of sperm motility. Front Biosci. 2006 May 1;11:1433-47.
100. Bonaccorsi L, Marchiani S, Ferruzzi P, Muratori M, Crescioli C, Forti G, Maggi M, Baldi E. Non-genomic effects of the androgen receptor and Vitamin D agonist are involved in suppressing invasive phenotype of prostate cancer cells. Steroids. 2006 Apr;71(4):304-9.
101. Bonaccorsi L, Nosi D, Muratori M, Formigli L, Forti G, Baldi E. Altered endocytosis of epidermal growth factor receptor in androgen receptor positive prostate cancer cell lines. J Mol Endocrinol. 2007 Feb;38(1):51-66.
102. Marchiani S, Tamburrino L, Maoggi A, Vannelli GB, Forti G, Baldi E, Muratori M. Characterization of M540 bodies in human semen: evidence that they are apoptotic bodies. Mol Hum Reprod. 2007 Sep;13(9):621-31.
103. Muratori M, Forti G, Baldi E. Comparino flow cytometry and fluorescence microscopy for analyzing human sperm DNA fragmentation by TUNEL labeling. Cytometry Part A, 2008;73(9):785-787.
104. Bonaccorsi L, Nosi D, Quercioli F, Formigli L, Zecchi S, Maggi M, Forti G, Baldi E. Prostate cancer: A model of integration of genomic and non-genomic effects of the androgen receptor in cell lines model. Steroids. 2008 Oct;73(9-10):1030-7.
105. Muratori M, Marchiani S, Tamburrino L, Tocci V, Failli P, Forti G, Baldi E. Nuclear staining identifies two populations of human sperm with different DNA fragmentation extent and relationship with semen parameters. Hum Reprod. 2008 May;23(5):1035-43.
106. Varano G, Lombardi A, Cantini G, Forti G, Baldi E, Luconi MSrc activation triggers capacitation and acrosome reaction but not motility inhuman spermatozoa. Hum Reprod. 2008; 23(12):2652-62.
107. Muratori M, Luconi M, Marchiani S, Forti G, Baldi E. Molecular markers of human sperm functions. Int J Androl. 2009; 32(1):25-45.
108. Bonaccorsi L, Nesi G, Nuti F, Paglierani M, Krausz C, Masieri L, Serni S,Proietti-Pannunzi L, Fang Y, Jhanwar SC, Orlando C, Carini M, Forti G, Baldi E, Luzzatto L. Persistence of expression of the TMPRSS2:ERG fusion gene after pre-surgery androgen ablation may be associated with early prostate specific antigen relapse of prostate cancer: preliminary results. J Endocrinol Invest. 2009 32(7):590-6
109. Baldi E, Luconi M, Muratori M, Marchiani S, Tamburrino L, Forti G. Nongenomic activation of spermatozoa by steroid hormones: facts and fictions. Mol Cell Endocrinol. 2009 Sep 24;308(12):39-46.
110. Muratori M, Tamburrino L, Tocci V, Costantino A, Marchiani S, Giachini C, Laface I, Krausz C, Meriggiola MC, Forti G, Baldi E. Small variations in crucial steps of TUNEL assay coupled to flow cytometry greatly affect measures of sperm DNA fragmentation. J Androl. 2010 Jul-Aug;31(4):336-45.
111. Marchiani S, Tamburrino L, Nesi G, Paglierani M, Gelmini S, Orlando C, Maggi M, Forti G, Baldi E. Androgen-responsive and -unresponsive prostate cancer cell lines respond differently to stimuli inducing neuroendocrine differentiation. Int J Androl. 2010 Dec;33(6):784-93.
112. Wendler A, Baldi E, Harvey BJ, Nadal A, Norman A, Wehling M. Position paper: Rapid responses to steroids: current status and future prospects. Eur J Endocrinol. 2010 May;162(5):825-830.
113. Baldi E, Bonaccorsi L, Nesi G, Serni S, Forti G, Luzzatto L. TMPRSS2: ERG fusion gene and androgen-ablation therapy in prostate cancer. Arch Pathol Lab Med. 2010 Jul;134(7):964-5; author reply 965.
114. Muratori M, Tamburrino L, Marchiani S, Guido C, Forti G, Baldi E. Critical aspects of detection of sperm DNA fragmentation by TUNEL/flow cytometry. Syst Biol Reprod Med. 2010 Aug;56(4):277-85.
115. Baldi E, Muratori M, Marchiani S, Tamburrino L, Fallet C. Fragmentation and/or decondensation of spermatic DNA: which consequences?. J Gynecol Obstet Biol Reprod (Paris). 2010 Apr;39(1 Suppl):14-16.
116. Lotti F, Corona G, Mancini M, Filimberti E, Degli Innocenti S, Colpi GM, Baldi E, Noci I, Forti G, Adorini L, Maggi M. Ultrasonographic and clinical correlates of seminal plasma interleukin-8 levels in patients attending an andrology clinic for infertility. Int J Androl. 2011 Dec;34(6 Pt 1):600-13.
117. Marchiani S, Tamburrino L, Giuliano L, Nosi D, Sarli V, Gandini L, Piomboni P, Belmonte G, Forti G, Baldi E, Muratori MSumo1-ylation of human spermatozoa and its relationship with semen quality. Int J Androl. 2011 Dec;34(6 Pt 1):581-93.
118. Muratori M, Marchiani S, Tamburrino L, Forti G, Luconi M, Baldi E. Markers of human sperm functions in the ICSI era. Front Biosci. 2011 Jan 1;16:1344-63.
119. Muratori M, Forti G, Baldi E. M-540 bodies interfere with TUNEL analysis in human sperm samples. Hum Reprod. 2011 Mar;26(3):729; author reply 729-30.
120. Lotti F, Corona G, Colpi GM, Filimberti E, Degli Innocenti S, Mancini M, Baldi E, Noci I, Forti G, Adorini L, Maggi M. Elevated Body Mass Index correlates with Higher Seminal Plasma Interleukin 8 Levels and Ultrasonographic Abnormalities of the Prostate in Men attending an Andrology Clinic for Infertility. J Endocrinol Invest. 2011 Nov;34(10):e336-42.
121. Paoli D, Gallo M, Rizzo F, Baldi E, Francavilla S, Lenzi A, Lombardo F, Gandini L. Mitochondrial membrane potential profile and its correlation with increasing sperm motility. Fertil Steril. 2011 Jun;95(7):2315-9.
122. Corona G, Baldi E, Maggi M. Androgen regulation of prostate cancer: where are we now? J Endocrinol Invest. 2011 Mar;34(3):232-43. Review.
123. Luconi M, Cantini G, Baldi E, Forti G. Role of a-kinase anchoring proteins (AKAPs) in reproduction. Front Biosci. 2011 Jan 1;16:1315-30. Review.
124. Baldi E, Luconi M, Krausz C, Forti G. Progesterone and spermatozoa: a long-lasting liaison comes to definition. Hum Reprod. 2011 26(11):2933-4.
125. Tamburrino L, Marchiani S, Montoya M, Elia Marino F, Natali I, Cambi M, Forti G, Baldi E, Muratori M. Mechanisms and clinical correlates of sperm DNA damage. Asian J Androl. 2012 Jan;14(1):24-31.
126. Corona G, Gacci M, Baldi E, Mancina R, Forti G, Maggi M. Androgen deprivation therapy in prostate cancer: focusing on sexual side effects. J Sex Med. 2012 Mar;9(3):887-902.
127. Tamburrino L, Salvianti F, Marchiani S, Pinzani P, Nesi G, Serni S, Forti G, Baldi E. Androgen receptor (AR) expression in prostate cancer and progression of the tumor: Lessons from cell lines, animal models and human specimens. Steroids. 2012 Aug;77(10):996-1001.
128. Lotti F, Corona G, Colpi GM, Filimberti E, Innocenti SD, Mancini M, Baldi E, Noci I, Forti G, Maggi MSeminal vesicles ultrasound features in a cohort of infertility patients. Hum Reprod. 2012 Apr;27(4):974-82.
129. Filimberti E, Degl'innocenti S, Borsotti M, Quercioli M, Piomboni P, Natali I, Fino MG, Caglieresi C, Criscuoli L, Gandini L, Biggeri A, Maggi M, Baldi E. High variability in results of semen analysis in andrology laboratories in Tuscany (Italy): the experience of an external quality control (EQC) programme. Andrology. 2013 May;1(3):401-7.
130. Meamar M, Zribi N, Cambi M, Tamburrino L, Marchiani S, Filimberti E, Fino MG, Biggeri A, Menezo Y, Forti G, Baldi E, Muratori MSperm DNA fragmentation induced by cryopreservation: new insights and effect of a natural extract from Opuntia ficus-indica. Fertil Steril. 2012 Aug;98(2):326-33.
131. Lotti F, Tamburrino L, Marchiani S, Muratori M, Corona G, Fino MG, Degl'Innocenti S, Forti G, Maggi M, Baldi E. Semen apoptotic M540 body levels correlate with testis abnormalities: a study in a cohort of infertile subjects. Hum Reprod. 2012 Dec;27(12):3393-402.
132. Cambi M, Tamburrino L, Marchiani S, Olivito B, Azzari C, Forti G, Baldi E, Muratori M. Development of a specific method to evaluate 8-hydroxy, 2-deoxyguanosine in sperm nuclei: relationship with semen quality in a cohort of 94 subjects. Reproduction. 2013 Mar 1;145(3):227-235.
133. Muratori M, Forti G, Baldi E. Presence of M540 bodies in human semen: techniques to detect them require attention. Fertil Steril. 2013 Sep;100(3):e13.
134. Kurpisz M, Fraczek M, Baldi E. Towards understanding infertility: inflammatory mediators in male reproductive tract. J Reprod Immunol. 2013 Nov;100(1):1.
135. Degl'Innocenti S, Filimberti E, Magini A, Krausz C, Lombardi G, Fino MG, Rastrelli G, Maggi M, Baldi E. Semen cryopreservation for men banking for oligospermia, cancers, and other pathologies: prediction of post-thaw outcome using basal semen quality. Fertil Steril. 2013 Dec;100(6):1555-63.e1-3.
136. Tamburrino L, Marchiani S, Minetti F, Forti G, Muratori M, Baldi E. The CatSper calcium channel in human sperm: relation with motility and involvement in progesterone-induced acrosome reaction. Hum Reprod. 2014 Mar;29(3):418-28.
137. Marchiani S, Tamburrino L, Olivito B, Betti L, Azzari C, Forti G, Baldi E, Muratori M. Characterization and sorting of flow cytometric populations in human semen. Andrology. 2014 May;2(3):394-401.
138. Gacci M, Baldi E, Tamburrino L, Detti B, Livi L, De Nunzio C, Tubaro A, Gravas S, Carini M, Serni S. Quality of Life and Sexual Health in the Aging of PCa Survivors. Int J Endocrinol. 2014;2014:470592.
139. Samavat J, Natali I, Degl’Innocenti S, Flimiberti E, Cantini G, Di Franco A, Danza G, Seghieri G, Lucchese M, Baldi E, Forti G, Luconi M. Acrosome reaction is impaired in spermatozoa of obese males: a preliminary study. Fertil Steril. 2014 Nov;102(5):1274-1281.e2.
140. Marchiani S, Tamburrino L, Ricci B, Nosi D, Cambi M, Piomboni P, Belmonte G, Forti G, Muratori M, Baldi E. SUMO1 in human sperm: new targets, role in motility and morphology and relationship with DNA damage. Reproduction. 2014 Nov;148(5):453-67.
141. Muratori M, Tamburrino L, Marchiani S, Cambi M, Olivito B, Azzari C, Forti G, Baldi E. investigation on the origin of sperm dna fragmentation: role of apoptosis, immaturity and oxidative stress. Mol Med. 2015 Jan 30;21:109-22.
142. Marchiani S, Vignozzi L, Filippi S, Gurrieri B, Comeglio P, Morelli A, Danza G, Bartolucci G, Maggi M, Baldi E. Metabolic syndrome-associated sperm alterations in an experimental rabbit model: relation with metabolic profile, testis and epididymis gene expression and effect of tamoxifen treatment. Mol Cell Endocrinol. 2015 Feb 5;401:12-24.