|
Volume 27, Issue 3 (May 2025) 27, 365–369; 10.4103/aja202436
Clinical predictors of successful outcomes for couples with nonobstructive azoospermic male partners undergoing micro-TESE
Kavoussi, Parviz K1; Gherabi, Nazim2; Saleh, Ramadan3,4
1Department of Reproductive Urology, Austin Fertility and Reproductive Medicine/Westlake IVF, Austin, TX 78746, USA
2Department of Medicine, Algiers 1 University, Algiers 16000, Algeria
3Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University, Sohag 83534, Egypt
4Ajyal IVF Center, Ajyal Hospital, Sohag 83534, Egypt
Correspondence: Dr. PK Kavoussi (pkavoussi@hotmail.com)
Originally published: July 23, 2024 Received: January 23, 2024 Accepted: April 9, 2024
| Abstract |
|
Nonobstructive azoospermia (NOA) is the most challenging and complex clinical scenario for infertile men. Besides circumstances such as hypogonadotropic hypogonadism, surgical sperm retrieval is typically necessary, and microdissection testicular sperm extraction (micro-TESE) is the procedure of choice for men with NOA desiring to father children with their own gametes. Micro-TESE results in the highest numbers of sperm cells retrieved for use with in vitro fertilization/intracytoplasmic sperm injection (ICSI) in comparison to all other techniques for surgical sperm retrieval in men with NOA. Several factors may affect sperm retrieval rate and ICSI outcomes, including the patient’s age, testicular volume, histopathological and genetic profile, and serum hormone levels. This article aims to review the medical literature describing predictors of successful micro-TESE and the outcomes of ICSI in men with NOA.
Keywords: intracytoplasmic sperm injection; microdissection testicular sperm extraction; nonobstructive azoospermia
Full Text |
PDF |
|
| |
| Browse: 1611 |
|
