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Abstract

Volume 27, Issue 2 (March 2025) 27, 225–230; 10.4103/aja202481

Association between maximal urethral length preservation and postoperative continence after robot-assisted radical prostatectomy: a meta-analysis and systematic review

Xiong, Tian-Yu1,2; Liu, Zhan-Liang1,2; Wu, Hao-Yu1,2; Fan, Yun-Peng1,2; Niu, Yi-Nong1,2

1Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

2Institute of Urology, Beijing Municipal Health Commission, Beijing 100050, China

Correspondence: Dr. YN Niu (niuyinong@mail.ccmu.edu.cn)

Originally published: October 22, 2024 Received: June 7, 2024 Accepted: August 6, 2024

Abstract

Urinary incontinence is a common complication following robot-assisted radical prostatectomy (RARP). Urethral length has been identified as a factor affecting postoperative continence recovery. In this meta-analysis, we examined the association between use of the maximal urethral length preservation (MULP) technique and postoperative urinary continence in patients undergoing RARP. We conducted a comprehensive search of PubMed, Web of Science, Embase, and the Cochrane Library up to December 31, 2023. The quality of the literature was assessed using the Newcastle–Ottawa Scale. A random-effects meta-analysis was performed to synthesize data and calculate the odds ratio (OR) from eligible studies on continence and MULP. Six studies involving 1869 patients met the eligibility criteria. MULP was positively associated with both early continence (1 month after RARP; Z = 3.62, P = 0.003, OR = 3.10, 95% confidence interval [CI]: 1.68–5.73) and late continence (12 months after RARP; Z = 2.34, P = 0.019, OR = 2.10, 95% CI: 1.13–3.90). Oncological outcomes indicated that MULP did not increase the overall positive surgical margin rate or the positive surgical margin status at the prostate apex (both P > 0.05). In conclusion, the use of the MULP technique in RARP significantly improved both early and late postoperative continence outcomes without compromising oncological outcomes.

Keywords: prostate cancer; prostatectomy; robot-assisted surgery; urinary incontinence

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Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.