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中文摘要

《亚洲男性学杂志》 2011; 13 (6): 895-897

《亚洲男性学杂志》 2011; 13 (6): 895-897

用来曲唑促进血清卵泡刺激素水平正常的非梗阻性无精子症病人精子发生的初步研究

Giorgio Cavallini, Giovanni Beretta and Giulio Biagiotti (意大利)

本文探讨了来曲唑(每天2.5 mg )是否能提高非梗阻性无精子症病人的精子数。我们研究了4名病人,他们的卵泡刺激素(FSH )以及其它激素水平都在正常范围以内,也没有精索静脉曲张或染色体异常。给病人服用来曲唑3个月,检测用药前、用药中、停药后一周的精子数、睾丸体积,以及血液中的促性腺激素、睾酮、雌二醇水平。所有病人在用药期间都检测到射出精液中有精子,促性腺激素和睾酮水平上升,雌二醇水平下降。这表明来曲唑能提高非梗阻性无精子症病人的精子数,但是还需要更多的包括对照病人的研究来确定这一效果。

关键词:来曲唑, 药物治疗, 非梗阻性无精子症,精子发生

此摘要文献来源:
Giorgio Cavallini, Giovanni Beretta and Giulio Biagiotti. Preliminary study of letrozole use for improving spermatogenesis in non-obstructive azoospermia patients with normal serum FSH. Asian Journal of Andrology 2011; 13: 895-897

 
Asian Journal of Andrology CN 31-1795/R ISSN 1008-682X  Copyright © 2023  Shanghai Materia Medica, Chinese Academy of Sciences.  All rights reserved.