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Volume 15, Issue 2 (March 2013) 15, 174–178; 10.1038/aja.2012.158
Ignorance but not bliss: too little is known about the determinants of semen quality
WCL Ford
Division of Reproductive & Child Health, University of Birmingham, Birmingham B15 2TT, UK
Correspondence: Dr WCL Ford, (wclford@blueyonder.co.uk)
Received 16 October 2012; Revised 21 November 2012; Accepted 22 November 2012 Advance online publication 14 January 2013
| Abstract |
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Criticisms of the data that have been presented to demonstrate a decline in sperm counts over time reveal problems with semen analysis methods and a lack of understanding of the genetic and environmental factors that determine a man's sperm count. Potential sources of error in the WHO semen analysis protocol and some areas of ignorance about the biological and environmental factors which can influence sperm counts are briefly discussed. I conclude that there is a need to include semen analyses in a large cohort study to fill the gaps in our knowledge.
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