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Abstract

Volume 15, Issue 3 (May 2013) 15, 350–353; 10.1038/aja.2013.37

Prostate cancer research in China

Shan-Cheng Ren*, Rui Chen* and Ying-Hao Sun

Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China

Correspondence: Professor YH Sun, (sunyh@medmail.com.cn)

Received 4 February 2013; Revised 6 March 2013; Accepted 6 March 2013 Advance online publication 22 April 2013

Abstract

Prostate cancer (PCa) research in China has been on a rocketing trend in recent years. The first genome-wide association study (GWAS) in China identified two new PCa risk associated single nucleotide polymorphisms (SNPs). Next generation sequencing is beginning to be used, yielding novel findings: gene fusions, long non-coding RNAs and other variations. Mechanisms of PCa progression have been illustrated while various diagnosis biomarkers have been investigated extensively. Personalized therapy based on genetic factors, nano-medicine and traditional Chinese medicine has been the focus of experimental therapeutic research for PCa. This review intends to shed light upon the recent progress in PCa research in China and points out the possible breakthroughs in the future.


Keywords:prostate cancer (PCa); genome-wide association study (GWAS); single nucleotide polymorphisms (SNPs); China

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