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Volume 17, Issue 4 (July 2015) 17, 628–632; 10.4103/1008-682X.154308
Behavioral mechanisms of mammalian sperm guidance
Serafín Pérez Cerezales, Sergii Boryshpolets, Michael Eisenbach
Department of Biological Chemistry, The Weizmann Institute of Science, 7610001 Rehovot, Israel
Correspondence: Prof. M Eisenbach (m.eisenbach@weizmann.ac.il)
| Abstract |
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In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different
potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using specific
stimuli – a temperature gradient, fluid flow, and a chemoattractant gradient, respectively. Here, we review sperm behavioral in
these mechanisms and indicate commonalities and differences between them.
Keywords: chemotaxis; rheotaxis; sperm behavior; sperm motility; thermotaxis
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