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Abstract

Volume 19, Issue 5 (September 2017) 19, 512–514; 10.4103/aja.aja_14_17

Testosterone treatment in older men: glass half empty or half full?

Brendan J Nolan1, Mathis Grossmann1, 2

1 Department of Endocrinology, Austin Health, Heidelberg, Victoria 3084, Australia
2 Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria 3084, Australia

Correspondence: Prof. M Grossmann (mathisg@unimelb.edu.au)

Date of Submission 13-Mar-2017 Date of Acceptance 06-Apr-2017 Date of Web Publication 26-May-2017

Abstract

In a series of randomized controlled trials published in JAMA and JAMA Intern Med, US researchers have examined the effect of testosterone treatment in older men with testosterone levels <275 ng dl−1 on coronary artery plaque volume,[1] cognitive function,[2] anemia,[3] and volumetric bone density.[4] While the trials have shown positive results with respect to improvement in anemia and bone density, longer-term studies are required to delineate the long-term risks and benefits in this population.

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